00:00Life, life, life, life, life, life, life
00:06And here is life, beautiful life, eager to blossom.
00:13The world invites us to new dawns.
00:19He gives us tears, singing hands
00:23And the sun that dazzles us
00:27The crisp air, enchanting us
00:31It fills us with joy and life
00:34Life, life, life, life, life, life, life
00:41Life, life, life, life, life
00:46As you know, the body's enemies are countless.
00:49Viruses and bacteria of all kinds
00:52Capable of causing illnesses that are sometimes serious, sometimes mild
00:55Like... a cold.
00:59Against microbes, the body has a police force made of white blood cells
01:02of which you, the lymphocytes, will soon be a part.
01:06And also other specialists, such as polymorphonuclear leukocytes, macrophages,
01:11antibodies and how many others.
01:14But the body is also attacked by all sorts of poisons.
01:18Toxins, gases, chemicals, some of which are natural,
01:21but others, most of them, are man-made.
01:25To protect ourselves against these toxins, we have specialized units,
01:29Detoxifying enzymes, small units that all our cells produce.
01:37We need to go back; they're waiting for us for lunch.
01:43Look at this traffic.
01:45With all these escape mechanisms, one can no longer breathe.
01:50Ah, I've arrived!
01:52Ah, what is it?
02:06Ah, what is it?
02:07Ah!
02:08Ah!
02:24Beware, intruders!
02:25Here in the Amidals, we are on the front line of defense.
02:29Look who's trying to sneak in.
02:32Do you recognize them?
02:40Excuse me, but bacteria are not easy to digest.
02:47Watch out, here comes more filth.
02:49Don't worry, chief, they're not germs.
02:51only dust from pollution or smoke.
02:54Oh, that's unhealthy too, isn't it?
02:56Well, enzymes must be watching further.
02:58They are used to dealing with this type of clientele.
03:12Come on, just a little more effort, old man.
03:14Come on, give me your hand, I'll help you.
03:17We are almost there, in the alveoli of the lung.
03:19We're finally going to breathe some fresh air.
03:43Oh, but that's not fair!
03:46We shouldn't send polluted bubbles.
03:51Just look at that one, seriously, what a mess!
03:54How awful, Burke!
03:59What is it that you have?
04:05Look, more pollution, Captain.
04:09Seen.
04:12Call to the macrophage.
04:13We detected toxic particles.
04:16Zone 35 of the pulmonary arterioles.
04:18It needs to be cleared as quickly as possible.
04:20Oh !
04:22Oh !
04:29Oh !
04:33It is absolutely essential to launch macrophages and other available white blood cells to pursue them.
04:37They will have difficulty finding them.
04:39These are chemical pollutants.
04:41How will they recognize them?
05:02Checkmate to the queen.
05:10If I were you, I wouldn't have done that.
05:12You see here, the madman...
05:13Checkmate!
05:16Hey, what if I moved my tower forward there...
05:19Ouch!
05:24But what is that over there?
05:25It certainly looks like it...
05:28It's pollution.
05:30Don't worry, it's outside the cell.
05:32It will be eliminated soon.
05:34Play on the right.
05:37It seems to me that it is a cellular pollutant.
05:39He might come in.
05:41No, we are well protected.
05:43There are certain pollutants that can pass through the membrane.
05:46I think I'll play that.
05:48Yes, I think so.
05:49You're doing anything because you're losing.
05:56The toxin is getting in!
05:57She enters the cell!
06:01What will have been the warning?
06:04Except that he can!
06:13We have spotted the enemy.
06:14He enters the cell.
06:17Too late.
06:18He went in.
06:29We are no longer able to track them.
06:36Chief, an enemy invasion over there!
06:39What is this ?
06:40Microbes?
06:41No, no, boss.
06:42It looks like pollution, like toxins.
06:45It's all black and it's moving towards the center, towards the core.
06:49The center must be informed immediately.
06:51Toxins, apparently.
06:53All black, heading towards the command post.
06:57Locate it quickly!
07:06Ah yes, I recognize you.
07:08Smoke pollutant, to be eliminated at all costs.
07:15Eliminate them before they reach the core.
07:19Otherwise, we are in great danger.
07:21Heh heh! That's my specialty, master.
07:24I belong to the anti-toxin brigade.
07:26That's the beast, I'll take it apart in no time.
07:29Say, are you alone?
07:30Uh, yes, alone, for the moment.
07:34Well, you'll need help.
07:36These are tough pollutants.
07:38Go quickly, while we're getting it started
07:39the ribosome factory designed to manufacture reinforcements for you.
07:43Stop the production lines.
07:45Initiate the synthesis of detoxifying enzymes
07:47specific to benzodiazepines.
07:49Immediately alert the relevant chromosomes.
07:51Urgent! Come on, come on, immediate execution!
08:10Chromosome 6, we're asking for chromosome 6
08:12for immediate production of detoxifying enzymes.
08:15Urgent! Chromosome 6, please!
08:18Nap time! We're allowed to take a nap from time to time.
08:22like everyone else.
08:34Okay, okay, that's fine, don't push me!
08:37I'm coming, I'm coming!
08:54A, C, T, G, A, A, T, A.
08:58Here are the genes for cytochromes, the detoxifying enzymes.
09:03Activation, immediate activation.
09:07Restriction enzymes.
09:09This way, please.
09:12Here, the beginning of the antitoxin gene.
09:15Cut.
09:17THANKS.
09:21Here, the gene of his message ends.
09:23Cut.
09:24There, after the A.
09:27Okay, now, exit from the cell nucleus.
09:29Heading to the ribosome factory.
09:31No, no, no, no!
09:32Idiot! DNA is the basis of information.
09:35and it must never leave the core
09:37where it is protected.
09:38Is that clear?
09:40Duplications are necessary; duplications must be made.
09:43Is that understood?
09:44The original remains in place, always, let's see.
09:46Otherwise, we lose valuable information.
09:48that we will never find again.
09:50But how many times do we have to repeat the same thing to them?
09:56We are lacking iron.
09:57Antitoxin enzymes need to contain iron.
10:00Iron!
10:01How can iron be found in proteins?
10:03Yes, without that, they won't have any strength.
10:05Through these orders to the spleen, the great iron reserve.
10:08Quickly, we don't have time to chat.
10:10Well, boss, if you say so.
10:17Hello, hello, spleen factory, immediate need for iron.
10:22Later, as a result of...
10:24Your call could not be completed.
10:26Please call back later, due to...
10:30The spleen factory, we urgently need iron for the factory at...
10:35This is the Pylor, the center of intestinal transit.
10:38Please check your contact's number.
10:40Here at Pylor, the center...
10:45It's definitely the spleen, I'm asking for the spleen, the iron reserves.
10:49Yes, sir, what can we do for you?
10:52Iron!
10:53We need iron to assemble detoxifying enzymes.
10:56Hello ?
10:56The spleen?
10:57Yes, sir, we are indeed the spleen.
10:59Please specify your order.
11:01I need two million!
11:03Uh, two million, three hundred and fifty thousand iron atoms for manufacturing...
11:06Yes, sir, for the production of detoxification enzymes,
11:09We have successfully registered your order, which will be executed immediately.
11:13Thank you for your call.
11:16So, is this messenger RNA coming?
11:20There you go!
11:21Okay, you're stopping the transmission of the current message.
11:25And you, there, paste the messenger RNA for detoxifying enzyme in its place.
11:33Quick, quick! Come on, ligasse enzyme!
11:35Get that to me quickly!
11:46So, what? Is it coming?
12:02So, is it coming, yes or no?
12:24So what do we do?
12:31You are detoxifying enzymes, aren't you?
12:34You must protect the body against poisons of all kinds.
12:38I have the feeling that you're missing something.
12:40But wait, what could it possibly be?
12:47Oh, I've got it! The iron, the armor, where is the iron?
12:51We placed an urgent order for the spleen.
12:53A convoy is en route.
12:55And at high speed, master!
13:02Hey, a train station?
13:04Yes, a marshalling yard.
13:06That's the spleen.
13:07We need to prepare a delivery.
13:09We can see iron, certainly.
13:21So, what's going on?
13:22When it's the pedestrian's turn to cross, it's not the train's turn to cross.
13:26But I have an urgent delivery.
13:28Iron can't wait.
13:33Oh, I have an urgent delivery.
14:02Look over there, those gatecrashers.
14:06Oh, that's not fair.
14:11That's not fair.
14:20Ah, the train, finally, it took you a long time, didn't it?
14:23A minor delivery problem, eh?
14:26But here it is, your iron.
14:27And by express delivery again.
14:28Top-quality scrap metal.
14:30Well, it's about time, we've been waiting for you for so long.
14:46That's what we were missing.
14:47Go ahead, you were the first.
14:58Ah, I swear, you're good.
14:59You're gorgeous.
15:00Okay, so, it's over, right?
15:02The null cell is a danger.
15:04And you have a mission to accomplish.
15:06So, let's go.
15:28The benzo toxins entered through the cell membrane.
15:31They advance in tight formation towards the core.
15:34And there is danger.
15:36Our detox enzymes are designed to protect the nucleus at all costs.
15:40And to defeat the aggressors.
15:42Attack!
16:09Scatter yourselves, there are several enemy units.
16:22That's it!
16:27It needs to be taken apart.
16:29His body alone will not be able to eliminate him.
16:42Ah, there was another one.
16:44Where is he?
16:51It's mine.
16:52You'll see.
17:03Oh dear, the core is affected.
17:05Be careful with the chromosome, there is a risk of mutation.
17:07But I'll get that one.
17:11But what is that noise?
17:36Counselor, the situation is serious.
17:38Ah, but what is it?
17:39But why all this noise?
17:42A damaged chromosome?
17:44It's chromosome 4.
17:45There is a risk of mutation caused by a poliochemical.
17:47That would be the...
17:49Yes, cancer, if the malfunctioning cell manages to multiply.
17:53And when they become numerous, it's bad, very bad.
17:56They invade the healthy cells and prevent them from functioning.
17:59But we...
18:00Let's not panic.
18:01We can still get through this.
18:03And how so, master?
18:05There are several ways.
18:06Our detox products can destroy the intruders.
18:09and our body's sentinels destroy the affected cells.
18:12Otherwise, it's serious, very serious.
18:13But reproduction has not yet begun.
18:16And we need to try repairing the damaged DNA.
18:18by our specialized enzymes.
18:20Trigger the excision repair plan.
18:22Absolute emergency!
18:29That's it, boss, let's go.
18:40Damaged genetic materials.
18:42I'm going.
18:51Ouch! Don't crush my hands, now!
18:53There, there! Put your foot on my shoulder!
18:56My nose! Watch out for my nose!
19:08To you, Igor!
19:15And there you have it!
19:18You're not going to start?
19:20I'm the one who assembles the DNA so that it fits together properly.
19:23It is up to me to think in order not to make mistakes.
19:25I do intellectual work, you know.
19:27So, you'll let me think about it.
19:48And you, pass me that piece, the long one.
19:50And you there, you're going to give me the red one.
19:53Now, this one, the square one.
19:55There you go, you hold that together for me.
20:03That's a fine piece of work.
20:05Now, the repair.
20:09Come closer, come closer.
20:20It's this way, this way, there you go.
20:22Very good, that's perfect.
20:23Now, take A's hand while G, on his side, goes and does the same thing with his neighbor.
20:28I mean the other A.
20:30Okay, now let's not move.
20:33It's good, it's nice, it's creamy.
20:35Well done !
20:39It's over.
20:41Repair done without error.
20:44Normal cell, good for replication.
20:53DNA repaired, everything is in order.
20:57All that remains is to put it all back into the chromosome.
21:06Well, nothing beats a little nap to recharge.
21:20You see, everything ends well.
21:22The human body has unsuspected resources to face adversity.
21:26Okay, let's see what's happening elsewhere.
21:29There you go, the toxins are destroyed.
21:30Very well, now we need the clearing teams.
21:35Calling all vehicles transporting lysosomes, please.
21:40Come on, come on, clean all this up for me.
21:50Look at the lysosomes, they are the stomachs of the cell.
21:54They digest the waste and then expel it outside.
22:03Digestion complete, ready for expulsion from the cell.
22:06Digestion complete, ready for expulsion from the cell.
22:09Okay, rejection allowed.
22:12Generic
22:27And, finally, enter here.
22:42But what is this filth?
22:45Various types of waste, things that the cell does not need, things that can be harmful to it.
22:50But don't worry, we're getting to the kidney, it will clean everything up.
22:55Look, here's a renal artery, so we're getting there.
22:58Ah, it was about time, it's not pretty, it makes stains, and look at me, I'm not
23:02not presentable.
23:03The kidney, the kidney, that's really the sand-cleaning center, in fact, that's right, n
23:07'Isn't that right?'
23:08Yes, indeed, more than a liter of blood passes through it every minute.
23:13The waste is treated and disposed of.
23:16And will we be all clean?
23:17Yes, you'll see. Watch out, hold on tight, here we come. We'll meet at the party.
23:22Are we there yet? Why do we have to behave ourselves, is it dangerous?
23:24No, no, don't worry, come on, it's a glomerulus, a filtration center, quite simply.
23:46But are we completely clean?
23:48Yes, not a single speck of dirt.
23:50But I told you so, the kidney washes whiter, even the most stubborn stains.
23:55Tell me, master, where does all this filth go?
23:58Well, they are rejected from the body.
24:18Ah, so that's where the waste goes, then?
24:21Yes, in the bladder.
24:23And then what?
24:25After that, but come on, it's very simple.
24:27Ah, it's very simple.
24:29Yes indeed!
24:31Yes indeed!
25:02Life, life, life, life, that's life.
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