00:00Despite the widespread large-cell lymphoma, we are witnessing an extraordinary improvement in prognosis.
00:16Thanks to the availability of numerous drugs and treatments available for these patients in the last five years,
00:25unfortunately we still cannot cure them all.
00:29Therefore, we welcome the new approvals, such as the latest one obtained in the third line,
00:39the Oncastuximab, which gives the opportunity to treat patients already heavily pre-treated,
00:50who have received more than two lines of treatment,
00:55because the vast majority of these patients are elderly, in any Italian hematology.
01:03Because the therapies approved in the third line, such as the bispecifics and the SSKRT,
01:09if they have not been used in the second line, are not easily accessible to all centers,
01:16because the SSKRT centers are limited, and those who are not SSKRT centers do not have the expertise or the organization to be able to use the bispecific.
01:27Well, the Oncastuximab is an effective treatment that works very quickly when it works,
01:36and we see it already within two months, which is quite tolerable.
01:45Moreover, it is easily accessible, it does not require recovery, and it is a time-finished therapy.
01:52So it has many advantages, the vast majority of patients can use it,
01:59even those who have already undergone a treatment with CAR-T, for example, and it is accessible to everyone.
02:08This is the most important advantage, in my opinion.
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