00:00dear viewers welcome to truth and trends sonia headlines say russia has a 100
00:14percent effective cancer vaccine enteromix that sounds like sci-fi but is it for real
00:21it does sound magical deepak but let's see what's behind the claim step by step
00:27enter mix is a personalized mrna vaccine here's how it works one scientists sequence your tumor's
00:35dna to identify unique mutations two they design mrna that teaches your immune system to recognize
00:43those as antigens three after injection your immune system attacks only the cancer cells
00:50this is akin to the technology behind covid mrna vaccines but tailored to each person and their
00:57tumor nice what did the trials show are they really saying 100 effective and safe in early phase one
01:06human trials with about 48 volunteers mainly colorectal cancer patients they reported 100
01:14immune response tumor shrinkage slowed progression and no serious side effects however small sample
01:22size and early stage trial so this is promising not definitive any work on other cancers yet yes
01:29development is happening for glioblastoma melanoma including ocular types and more difficult tumors
01:36russia is gradually expanding the candidate cancers for enteromix this could be a game changer for india
01:41too right especially colorectal cancer is rising among youth absolutely but there are challenges personalized
01:50mrna vaccines need genomic profiling cold chain storage and rapid manufacturing not always easy in many
01:57settings plus regulatory clearance and price will determine reach so final takeaway is it hope or
02:06high it's a strong hope early data is exciting but we need larger phase 2-3 trials peer-reviewed data
02:13long-term effectiveness and safety profiles if confirmed this could redefine cancer treatment
02:20transitioning from chemo to smart immunotherapy viewers what do you think miracle of medicine or just
02:27early optimism let us know in comments like share and subscribe to truth and trends
02:33will keep watching this story and other medical breakthroughs until next time stay hopeful stay scientific
02:40jai hind
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