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Senior consultant pediatrician and Chairman of Nephron Clinic, Professor Dr Sanjeev Bagai, warned that severe air pollution is causing irreparable multi-generational damage to public health in India. He highlighted that ultrafine particulate matter, toxic gases, carcinogens, and micro-nanoplastics penetrate deep into the bloodstream, crossing the blood-brain barrier and damaging DNA chromosomes. Dr Bagai noted severe health outcomes, including stillbirths, congenital heart defects, childhood leukemia, stunting, and increased cancer risks. He stressed that preconception exposure for prospective parents alters genetic material, impacting future generations. Calling for urgent policy measures, Dr Bagai asserted: 'We need a separate ministry to combat air pollution.' He demanded an iron-fisted five-year implementation plan led by doctors, scientists, and environmentalists to eliminate road dust, establish no-traffic zones, regulate construction, and improve public transit.

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00:00All right, joining us next is Professor Dr. Sanjeev Bagai.
00:04He's a Senior Consulted Pediatrician Chairman at the Nephron Clinic.
00:07Hello and welcome, Dr. Bagai.
00:09I don't remember for how many years exactly we've been talking about the same issue.
00:15Year on year, we keep talking about the number of kids who are impacted by air pollution.
00:21Year on year, we've spoken about the pregnant women who are impacted by air pollution.
00:25Year on year, we've spoken about heart being impacted by air pollution, knees being impacted,
00:33you getting, you know, migraine because of air pollution, diabetes because of air pollution.
00:38The list is just endless.
00:40In fact, recently, I met one of the country's top oncologist who said that if you are constantly living in
00:47polluted air,
00:49you are now at high risk of cancer.
00:52Now, these are not scary headlines to tell people.
00:54I want to hear from a doctor like you on how much of it is actually translating into visits in
01:00the clinic.
01:02Good afternoon.
01:04I think it's a sad narrative on comprehensive systemic decay.
01:09Right from policymakers to the implementers to the law enforcement and indeed the society at large.
01:17When you talk in terms of air pollution, we've said this many times over, you know, in Hiroshima and Nagasaki,
01:24we lost two lakh individuals.
01:27In COVID, over four years, we lost six lakhs Indians.
01:31Every year, we are losing 20 lakh because of air pollution.
01:35Let that sink in.
01:36It's 25 times the effect of mortality of COVID.
01:40And we thought COVID was a pandemic.
01:42This is an actual debacle what we are facing.
01:46So, very quickly, of all the ingredients, be it PM2.5, toxic gases, SOX, NOX, the volatile organic compounds, hydrofluorocarbons,
01:55carcinogens, radioactive materials, heavy metals, oxidized into super ions as micro-nanoplastics.
02:03They form small, little, ultrafine particles which puncture through the lungs.
02:08They reverse the lung flow, enter into the bloodstream, cross the blood-brain barrier, damage every organ possible, including your
02:16bone marrow and indeed your DNA.
02:18What happens in your DNA is that either your methylation, that means your metabolism of your DNA goes up so
02:26much or down so much that your DNA chromosomes start breaking.
02:30Once those chromosomes are broken or damaged, then your generations are lost to come forward.
02:36We have seen this with early pregnancies, still births.
02:40We've seen this with premature deliveries.
02:42We've seen it with children being born with congenital heart disease as two times the increased risk.
02:48Absent limbs.
02:49Can you believe children being born with absent fingers or indeed absent upper arm?
02:54We have been seeing that children can be born with one kidney instead of two or an abnormally placed urinary
03:00bladder or indeed facial dysmorphism.
03:03We've seen children who are at high risk of developing leukemia after birth.
03:07Even after the farm fires stop, individuals who have been exposed to it, that means us in Delhi,
03:15we are at risk of cancer for 20 years because that's the time it takes to heal the body.
03:21So we need to do something.
03:23We need to do something as per yesterday, but we need to act very quickly.
03:27Every one month of exposure increases the risk only by 10 micrograms of PM 2.5.
03:33And here we have crossed 3,700 in Delhi.
03:37When we are looking at 10 micrograms increase, the risk of CA breast increases by 20%.
03:42So what we are going to actually see amongst all the other abnormalities is huge amount of chronic diseases coming
03:49up.
03:49There will be a burst of cancers all over.
03:52Their children are being born now with anemia.
03:54The bone marrows are getting destroyed.
03:56The heart, the silent heart attacks, the strokes, dementia by 63% increase.
04:02And all these ingredients cause what we call as oxidative stress.
04:06So these are inflammatory molecules.
04:08They go through the bloodstream.
04:10They activate your genes.
04:11I'll just take 15 seconds in this.
04:14If your PM 2.5 is placed at 46 micrograms, that means just double of what WHO limit is,
04:21you activate.
04:23That means your genes get hyperactive of 540.
04:27Now increase this to 96 micrograms.
04:30That means four to five times the WHO limit.
04:33You have more than 1,900 genes which are damaged.
04:36So this is dose dependent.
04:38That means impact dependent.
04:40That means duration dependent.
04:42I dare say there will be thousands of genes in our body which are already been impacted or damaged.
04:48So we need, this is tackleable.
04:50The sad story is that this is tackleable.
04:52We need an intent and we need proper content to implement.
04:56We need a separate ministry to combat air pollution.
05:00This is a worse thing which is happening to Indians at the present moment.
05:06Elections can stay.
05:07Your vote bank politics can go for a toss.
05:10Religion can be parked aside for many months.
05:13This is important because if we don't live, we will not be there to vote.
05:17If we are not alive, we will be not, we won't be there to pray.
05:21I think we need to get our act together.
05:23And if there is a particular person who can do it, it's the central government at the present moment.
05:28We just need an iron hand to whip it and make sure that things are implemented.
05:36Dr. Buggai, help me understand how many generations of impact are we looking at with air pollution?
05:41And you're saying a genetic modulation, does that mean that not just the current generation and our kids,
05:48but those who follow might also have those, you know, those changes?
05:54Absolutely.
05:54So this is proven scientifically.
05:57And very often the naysayers and the unscientific people in our community tend to doubt the science.
06:03This is medically proven.
06:04They've done huge amount of next gene sequencing studies on the mothers, on the fetuses, on the babies and the
06:13parents.
06:14Longer the exposure, greater the extent of damage.
06:17Babies are going to face this for the next many, many decades in their life, the ones who are going
06:21to be born.
06:22The important point is, can you believe it?
06:24That an expectant mother, preconceiving, that means even before a young couple plans to conceive,
06:32if the lady has been exposed to this kind of toxic air for 12 months before the impact is already
06:38there.
06:39So, you know, this is huge.
06:42And I want people to understand that if this is one thing which is going to destroy our dream
06:48of becoming 2047 Viksit Bharat or a developed nation, it's going to be air pollution.
06:54Our growth stunting of our children is 23% because of air pollution.
07:00Our cognitive function is down 63% because of air pollution.
07:05Higher amount of vascular strokes, higher amount of medical emergencies like heart attacks,
07:11of hypertension, of diabetes.
07:1420 to 30% of the world's diabetes is because of air pollution.
07:18This is all published in Lancet.
07:20When you look at materials like micro-nanoplastic,
07:24every Indian is inhaling or ingesting 1.2 lakh microfibers of micro-nanoplastic.
07:31These fibers can never be digested or excreted.
07:35These are deposited in the body.
07:37There are studies to show micro-nanoplastics are even there in the cardiac plaque.
07:41We keep blaming the bad cholesterol and the good cholesterol and lifestyle.
07:45This is what is there in the heart attack.
07:48When you get a blood clot, the clot has micro-nanoplastic.
07:53Alzheimer's, Parkinsonism, dementia, the list just goes on and on and on.
07:59People should understand that these are inflammatory markers which reactivate your pro-oncogenes.
08:06That means your silent genes become active.
08:10The people who are sitting quietly are now being made into rust.
08:13If the science is so clear, and like I said in the beginning, doctor after doctor I speak with is
08:19sounding an alarm.
08:20How is it that our government has not woken up to it?
08:23Measures are being, you know, followed.
08:26There seems to be finally some chatter about air pollution in the political corridors.
08:30But action is still far, you know, behind at the moment.
08:34Why do you think the government has not woken up to this?
08:37Is the doctor community doing something about it to ensure that they send a memorandum perhaps?
08:43They send a letter to, you know, the Prime Minister or to others in power to say that,
08:48listen, you've got to do something at war footing.
08:51You know, like I said, we managed major catastrophes extremely well.
08:57In fact, we managed it better than the rest of the world, vis-a-vis the COVID and its rollout
09:01of the vaccines.
09:02If we can circumvent that, there is no reason why we can't get control over this.
09:07It's not going to happen in a month.
09:08And I dare say it will not even happen in a year.
09:11But let's have a five-year rollout plan.
09:14Let's keep realistic goals.
09:16Like I've always said, we need a separate ministry to combat air pollution.
09:20Yes, there will be a minister, whether we like it or not.
09:23But the real fact is, we need it driven, thought through, visioned, implemented through scientists, doctors and environmentalists.
09:32Let there be a strong implementation norm.
09:35There is no reason why we cannot control traffic emission.
09:39BS4 and BS3 and BS6 is not going to help.
09:42We have to have no traffic zones like Cannot Place in the evening or Lachbat Nagar or Sorojani Nagar market
09:48for that matter.
09:49We need better public transport.
09:52Road dust can be eliminated.
09:54There is no rocket science in this.
09:56World over, you can do it.
09:57But if you only lay half the road and the contractor eats half the money, then this is what we
10:01are going to get.
10:02The vendors have to be off the streets because that is causing idling of the cars and road congestion.
10:08Most importantly, construction norms have to be obeyed with.
10:11We have to be disciplined as a community.
10:15We are paying the price of lack of discipline.
10:18We are paying the price of thinking it's someone else's problem.
10:22Pollution is not an abandoned child.
10:25This is something which is going to kill us, kill us for sure and kill us very quickly.
10:30And that death is going to be pretty miserable.
10:33All right.
10:34Like I said, hard words there and something that all of us need to, you know, sink in with the
10:40point that Dr. Baga is really making is that while, you know, like COVID or like what happened in Hiroshima
10:47and Nagasaki, the impact was immediate.
10:49With air pollution, it slowly but surely kills you.
10:53It's tripping away years of your life, month after month, hour after hour, every breath after every breath.
11:02That's what's really happening with air pollution.
11:04And if we don't wake up to take some action, it's going to impact all of us.
11:08It's a massive equalizer.
11:10It will spare nobody right from those who sit in massive bhavens to those who sit on the streets as
11:16well.
11:16For the moment, Dr. Baga, thanks so much for joining us with your perspective.
11:18If.

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