00:00Scientists may have found a new way to help cancer treatments work for longer.
00:04Researchers at Memorial Sloan Kettering Cancer Center discovered
00:07that immune T-cells don't simply run out of energy.
00:11They burn through it too quickly.
00:13The study identified a molecule called MEK as a key driver of this process,
00:18causing T-cells to become exhausted and stop attacking cancer effectively
00:23by blocking EMEC in laboratory studies.
00:26T-cells used less energy, survived longer.
00:30And stayed ready to fight tumors.
00:31The findings could improve several forms of immunotherapy,
00:35including checkpoint inhibitors.
00:37CAR-T-cell therapy and tumor-infiltrating lymphocyte therapy,
00:41researchers say FDA-approved MEK inhibitors already exist,
00:46meaning this approach could move to human clinical testing more quickly.
00:50Scientists caution the treatment may not suit every patient.
00:54But the discovery could help create longer-lasting,
00:57more personalized cancer immunotherapies in the future.
01:00C-cells-tell therapy may not suit every patient,
01:00as they feel visible for the patient.
