00:00Scientists have mapped about 1 million of the body's most common immune cells.
00:04These white blood cells, called neutrophils, help fight infection and repair tissue.
00:09The new atlas combines 43 data sets covering 781 samples from more than 20 tissues and diseases.
00:16The data came from 9 countries and 7 sequencing platforms.
00:21Certain neutrophil patterns were linked to more severe COVID-19 and bacterial sepsis.
00:26Other signatures were linked to poorer metabolic health and diabetes.
00:29In tumor samples, some inflammatory patterns were tied to poorer survival.
00:34Signatures related to a gene called CD74 were linked to better outcomes.
00:39Health records from 430588 patients were also analyzed.
00:43Higher neutrophil counts, even within the normal range, were tied to higher chronic disease risk.
00:48The findings come from past data and cannot prove cause and effect.
00:52Prospective studies are needed before the approach could guide patient care.
00:56The study was published in the journal Nature Immunology.
01:00Disclosure.
01:00This video contains stock footage and content created or enhanced using AI-assisted tools.
