00:00Mitochondrial DNA levels in cancer cells link closely to tumor growth in chemotherapy response.
00:06Researchers publishing in the EFEBS journal analyzed multiple cancers
00:10and found mtDNA copy number correlates with genetic mutations inside tumors.
00:16Higher mtDNA levels appear to compensate for damaged mitochondrial function in cancer cells.
00:21This change also matches shifts in gene activity tied to how cancer responds to chemotherapy.
00:27Notably, high mtDNA copy numbers connect with genes that promote tumor survival and growth.
00:33Ritaman Dhar, a lead researcher at the Indian Institute of Technology, Kharagpur, said,
00:38Our results reveal a close association of mtDNA copy number with cancer progression and therapy response.
00:46These findings could open new paths for cancer treatment by targeting mitochondria.
00:50Understanding mtDNA's role might reshape how doctors manage cancer in the future.
00:55Disclosure. This video contains stock footage and content created or enhanced using AI-assisted tools.