00:00Scientists say they may have found a crack in one of the deadliest cancers there is.
00:05Researchers at Ohio State's Comprehensive Cancer Center have identified a possible weak spot in
00:10glioblastoma, an aggressive brain cancer notorious for surviving both radiation and chemotherapy.
00:16In preclinical experiments, blocking a protein called SET completely prevented tumors from
00:21forming. Targeting related proteins alongside it made the cancer cells far more vulnerable
00:26to radiation treatment. The strategy works by restoring the activity of an enzyme called
00:31PP2A, which glioblastoma cells normally shut down in order to survive and resist treatment.
00:37Researchers are quick to point out this isn't meant to replace existing therapies,
00:42but rather to make radiation and chemotherapy work harder against the tumor. It's still early.
00:48Human trials are needed before doctors know whether the approach is safe and effective for patients.
00:53But for a cancer that's seen few real treatment advances in decades, scientists say this discovery
00:59offers a genuinely new direction. Disclosure. This video contains stock footage and content
01:04created or enhanced using AI-assisted tools.
