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فسيلة - transplant
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هي مكتبة رقمية تحتوي علي آلاف الفيديوهات العربية في جميع المجالات
It is a digital library containing thousands of Arabic videos in all fields.
قوائم تشغيل فسيلة
https://www.dailymotion.com/fasela/playlists
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LearningTranscript
00:00Dear viewers
00:01I, Dr. Frederick Simpson, would like to announce
00:04And my colleague Dr. Sayed Samba
00:06After ten years of laboratory studies
00:10Regarding the discovery of a dangerous property and residence called Anbil
00:14No, but we're really happy, to be honest.
00:17The very happy ones
00:18The happy ones are not just very happy, but
00:20The happy ones are strong
00:21The happy ones are happy, that's the cart.
00:24Mr. Di, we are live
00:25Anabyl has been tested in several studies including
00:50AHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAHAH
00:51The safe of the thief, Shock Face
00:53The safe of the thief, Shock Face
00:55Everything is on the side
00:56Oh, my dear, we've already proven that you actually did all of this.
00:58And because I am a thief, a cheat, a deceiver, and a despicable person
01:03This gives you the right to call it a destructive relationship.
01:05I think so, yes.
01:06That's how it is, I'm going to resign.
01:10And the limit is that it returns to me with a slap
01:11I'm not going back to that job again
01:13Mr. Ah, this is Mr.
01:14What's up, Ali?
01:15I was determined to stand with you, my brother.
01:16Now take my belongings
01:17And I don't want anything from you
01:19Oh man, oh my dear, for your information
01:21I am Amer Al-Shahab Kaban Ali
01:23May this day be filled with meteors
01:25I'm leaving
01:27Hey sir, where are you hiding?
01:28Hey sir, wait
01:32You have been
01:34present
01:42Ah, just like the two scenes of prayer and blessings. Welcome to a new religious episode of the Al-Daheeh program.
01:46In 1995, Purdue Pharma submitted a request for
01:50The FDA stands for US Food and Drug Administration.
01:52You know this company is applying to the FDA
01:54In order for a new drug to be approved
01:57Axy Contin
01:58Two pharmacists from Jerjin are paying attention and writing to us with the correct pronunciation in the comments.
02:01This drug is one of the opioid painkillers
02:03Opioids
02:04But what's different about this drug is that it promises a safe pain reliever.
02:08It won't make the person who takes it addicted.
02:10And a quarter and a half, and this weather is not available, God willing.
02:12The medicine, my dear, is approved and achieves great sales.
02:14It reached $44 million in 1996
02:17But people are still worried about him.
02:19Here, dear FDA, you will follow the medication instructions regarding the delayed absorption of these tablets.
02:22It makes it non-addictive
02:24Take the quantities you want
02:26Don't worry, you won't become addicted to these painkillers.
02:28Because it sucks slowly
02:29Here, dear doctors, I say to his wife, and he is reassured.
02:31Sales of the drug increased by one billion dollars in 2000.
02:34God, Abu Ahmed, it's a powerful painkiller.
02:35Oh Abu Ahmed, that's a nice story!
02:37Oh, so the drug came out and got FDA approval, and they made a billion dollars.
02:41So, why are you here? What's up, my dear? I can't tell you some good news, can I?
02:44I need to bring you news and a nest.
02:45So, Abu Ahmed, you always know your secrets
02:46A country occupied by a man who kidnapped a woman who forgot her son in Arabic
02:50It means you always like to enter in my size
02:52Okay, my dear, you like the measurements, so take an hour.
02:54What's wrong, Abu Ahmed? What did he take it for?
02:56Let me, my dear, reveal something behind the scenes.
02:57And I'm telling you that Curtis Wright is an FDA employee
03:00The person who was responsible for examining and reviewing the data for this drug
03:03He will leave the government organization later, and he won't be rejected.
03:06This will lead to a higher position.
03:08I've noticed, Abu Ahmed, that the news is still good.
03:09Cover us
03:10Hemske holds a senior position at Purdue Pharma.
03:14With a huge salary
03:15He told her, "It's not for Abu Ahmed; in business terms, it's called a conflict of interest."
03:18What conflict of interest? This is a clash of interests.
03:21What's the matter? It doesn't take a genius to figure it out.
03:22And TikTok will build when reality surprises us with terrifying statistics.
03:25With the arrival of 2000, addiction cases will increase dramatically.
03:28Opioid-related deaths will increase by a factor of several times over.
03:32Especially in which states, my dear, has this drug become widespread?
03:36Here, my dear, the FDA accepted the company officials.
03:38Guys, we want to make the world a better place.
03:40The medicine is killing people.
03:41You're right, my dear, I've really got their minds working on a brilliant and ingenious solution.
03:44It might open my mind
03:46They're thinking, my dear, they're thinking
03:47Until you arrive
03:48We're going to remove the front label for delayed absorption.
03:52So when people go to take the medicine, they will read what is said in the text.
03:56What is this you're meeting?
03:57There is no evidence that absorption is delayed.
03:59No, we won't buy it.
04:00Because we might get addicted to it.
04:01Not only that
04:02We'll also put up Black Box and Ring
04:04Black box warning
04:06for him?
04:06For the person who buys the medicine
04:08He will always read what is written.
04:10What will I find?
04:11This is the highest level of warning you can put on a product.
04:13I won't take it because I might get addicted.
04:15I really want to see the movement of the carpet companies.
04:16He sends you a picture of a black lizard that looks like this?
04:18So of course you refrain from smoking
04:20Unfortunately, my dear, it was too late for this solution.
04:22The cases of the two sons will start to trigger an alarm at another organization.
04:25It will become the D.E.A.'s attention.
04:27Not Jab and Hamid, the one who makes cheddar cheese
04:29The one who was at the police station in Breaking Bad
04:30Those who always ate donuts
04:32That's exactly it.
04:33Indeed, dear Drug Enforcement Administration
04:35For the first time in its history, it will set a national action plan to combat the drug
04:38The 2007 case against the pharmaceutical company
04:41She is fined up to $634 million.
04:46Okay Abu Hamad, I'll put my mother in a new rental.
04:48Treatment misuse is being addressed
04:50Here, the officials mentioned that they would pay the fine.
04:52They went back and continued their work on the rest of the medications.
04:54God brought, God took, God is on the crooked
04:56But my dear, he'll discover that the matter is over.
04:58And this won't be their last case of extremism.
05:00On the contrary, this legal battle, my friend, is just beginning.
05:03Oh Abu Hamad, there's another three-letter word that's upsetting.
05:05I wish it had come from another direction.
05:07This is a farm with resources
05:08Approximately 3,000 state and federal cases
05:11They filed a lawsuit against Purdue Pharma.
05:13These cases will increase the overall penalties
05:16Exceeds eight billion dollars
05:19The day of the Sodium was what I did
05:21So, my dear, we'll see in 2019
05:23The company is filing for bankruptcy
05:25Pharma Hart
05:26The company, my dear, tells her name
05:27She also admits that she defrauded health organizations.
05:30Huge bribes were paid to officials
05:32This painkiller was marketed to doctors through targeted scientific research.
05:36Or other research that has been misrepresented to serve the interests of the pharmaceutical industry.
05:39Ah, Abu Hamad, this is the other side of science.
05:41Why are you talking so much about what you're saying?
05:43Specific
05:43Mansh, I'm Abu Hamad, and whoever doesn't know me, I'm doing a good deed.
05:46Opium is known to cause addiction.
05:47That's all the drama and cinema.
05:48All the founders know him
05:49The scientists will be the ones in white jackets.
05:51We don't know him
05:51Hey, my dear, let me tell you
05:53Our reliance as humans on a dangerous substance
05:54And you, Triki, like opium, with a pain-relieving fringe
05:57It wasn't anything we chose at all.
05:58So if he has a pain in his back
06:00Or a barren role or a toothache
06:01Or even a mild case of COVID that we're fighting with this ignoring.
06:04A pandemic we denied
06:05So, we broke up with COVID, and he just accepted it and left.
06:07Any minor aches or pains you have
06:09What will you give him? You'll give him Panadol.
06:10You won't have to think anymore, I'll take this disc first.
06:12I'll become addicted and have side effects that will torment me.
06:15no
06:16But my dear, until approximately the end of the 19th century
06:18Pain relievers for daily and chronic pain were unavailable.
06:22Opium is not his energy.
06:23Panadol in our couscous bag is a luxury.
06:25Something like that, we took it for granted
06:26The kings of their time did not own it.
06:28The king of the country says that he has no pain left.
06:30The best thing would be for him to take a shot of opium and become addicted.
06:33My dear, the widespread success of the OxyContin drug
06:36It wasn't just because of marketing, bribery, and biased research.
06:39Opium at that time was part of a major shift in the medical community.
06:42Your magazine
06:42At this time, you will write that we prescribe fewer painkillers than necessary for patients.
06:48And patients aren't being treated for their pain because of the barriers we've put in place.
06:51So I left you fresh, a natural community
06:53Let people find relief from their pain.
06:54Why are you preventing happiness?
06:55Be aware that during this same period, vital signs will be added
06:58Those who take risks are given to patients so that they can assess the condition.
07:00Such as the patient's temperature, pulse, blood pressure, and respiratory rate.
07:04Five vital signs are added to them, namely pain levels.
07:07In countries like America, pharmaceutical products are marketed on television; it's become a media business.
07:11Its size in America in 2016 reached six and four tenths of a billion dollars
07:15Here it became easy for the patient to go and get these
07:18Because he saw his advertisement on television
07:19Up until now, my dear, the television has given me credit for anything in the world.
07:22I mean, I might be someone who hasn't been convinced by any of the words I've heard in the past few years.
07:25But he loves one thing: health and beauty.
07:27In the eyes of the citizen, television means credibility.
07:29Especially since painkiller pills are easier, cheaper, and pose more risks for the lazy.
07:33If you're telling me about an expensive treatment program
07:35Especially if I'm in a country with no strong health insurance.
07:37So, get me the painkiller, give me some peace, let them work.
07:40But we'll sit here and search from within, fix from within, and repair.
07:44Because I have neither the time, nor the energy, nor the effort, nor the money, and we don't guarantee the system.
07:49Please give me the pill quickly, I need the dose.
07:51But at a time when modern capitalism transformed the painkiller from a mere real estate item into a television star, a magic solution, and a public dawn
07:58The truth is that humankind has been searching for a solution to this since time immemorial.
08:00Thousands of people were not using OxyContin advertising because of what the FDA said.
08:04The two words spoken by the FDA are not responsible for the success of the drug.
08:07But a large part of the drug's spread stemmed from the fact that people were already willing to believe it.
08:11We want the pill we take to be okay.
08:14I had a humanitarian need; you told me you had one.
08:16So you don't need to put in any effort, just follow it.
08:18And I don't need to exert any effort to doubt you.
08:20People were driven by a deeper human instinct.
08:22The need for effective and safe housing
08:25Patients are offering relief from a condition for which many medications have failed to cure them.
08:28Or alleviate their pain
08:29We're also here for more than just the idea of accommodation.
08:31Pain relief
08:33We naturally have an instinctive drive to alleviate pain.
08:36My dear, the idea is that things that kill pain
08:38It's not just that it's beautiful because it kills the pain.
08:40But sometimes it's beautiful in itself
08:42It has a positive effect on the brain.
08:43Let me tell you for example
08:44Animals in experiments where food containing painkillers was offered
08:47She used to eat more of it than regular food.
08:49It has been said, my dear, that sometimes pain
08:51And look, this person is more of a friend than an enemy.
08:54Seriously, Abu Ahmed, you didn't know, I said it in 500 episodes only.
08:57Pain, by its very nature, is a great blessing.
08:59To understand its importance, let me introduce you to Steve Pitt.
09:01This man, my dear, feels no pain.
09:03This man, my dear, puts his hands in boiling water.
09:05It's like he's eating chips with salt and doesn't care.
09:07My dear, it's possible to perform a complete surgery without anesthesia.
09:10Dr. Fatih and his work, and he's cutting into it
09:12Tick tock tick tick tick tick tick
09:13And he keeps flipping through the reels.
09:14Oh Abu Ahmed, take this man and let him pass through the iron
09:27He can endure a beating from the ground, but he won't get tired.
09:29If this is the goal, it means a thief's idea is hanging from a post.
09:32The correct answer, my dear.
09:34In his childhood, Steve was running around and bumping into things.
09:36He paints his picture and wounds without realizing it
09:38Aziz sometimes used to suck his tongue while eating.
09:40Without him realizing there was a problem
09:41During his life, he broke 80 bones in his body.
09:43He didn't feel the pen
09:44His branch is dear to the doctor
09:45As for the doctor, he brought the ladle and kept it under his foot, warming it up.
09:48It heats up continuously like this
09:49Secondly, Abu Ahmed, is this Tajid, his leg?
09:51The man, my dear, kept burning until his skin was burned.
09:53Abu Akhad, a needle was sharpened, and its instinct was in his back.
09:55My reaction was not...
09:56Here the doctor concluded that he was suffering from a condition called
09:58Congenital palliation
10:01The public, my dear, is a monitoring device.
10:04It alerts us that there is a problem
10:05It needs to make you stop everything and pay attention
10:07Focus, you need the doctor to look at this lesson.
10:09You need to do things on your leg
10:10There's a problem here; this is where we need to take action.
10:13Normally, my dear, you might not be able to control your body.
10:16Until you feel your pain
10:17It feels like you can hear your own heartbeat
10:18And you can feel your bowels moving
10:20Any brush around you makes you happy and distracts you
10:22All of this is to try and find out the cause of the problem.
10:24In short, we can call pain a friend.
10:26I want you to diagnose and treat it.
10:27That's why, my dear, the most insidious diseases are those that cannot be cured, and make
10:30For example, some cancers in their early stages
10:33The latest ones happen without any pain.
10:34Pain has long driven humankind to seek explanations and treatments to alleviate it.
10:38And here humanity will try in two paths or routes connected to each other
10:41Understanding how this pain occurs
10:43And how to find a way to teach
10:44For example, early humans understood the concept of pain.
10:47Which is the result of an injury or a plan
10:48But the unexplained, invisible pain that comes from inside the body
10:52It was very confusing for them
10:53It means my stomach hurts without me bumping into anything.
10:55So here they believed that this was happening because of evil gods.
10:57Or perhaps evil spirits or demons remained and infiltrated the body through its openings.
11:02And make this certain: the devil entered through my navel.
11:03May God help him
11:04Therefore, the treatments were part of the diagnosis.
11:06So that the thing that invaded the body can leave
11:08This was where vomiting, sneezing, and urination were described.
11:11Or even making wounds that store spoiled fluids
11:14So that they would allow the demons to escape with her.
11:16This might explain the phenomenon
11:17It existed in many ancient cultures
11:19It is a skull fracture.
11:20Of course, the pressure of incantations and religious rituals
11:22Magical amulets, icons, and sculptures
11:25The one who was its goal scorer
11:25Exorcising or appeasing demons to prevent trouble
11:27However, there is another approach that doesn't necessarily link treatment to diagnosis.
11:31But rather, the observed experience
11:32This is the basis of the scientific method.
11:33What are you doing right now, my dear?
11:35I'm nothing, Abu Hamid
11:35Come with me, I'll take you by the hand.
11:37Let's go visit ancient Egypt.
11:39God, Abu Hamid, these are definitely normal.
11:41Except, my dear
11:41He made me squat and he threw you into the Nile
11:43That's their custom
11:44That's their tradition.
11:45Let's take ancient Egypt as an example.
11:47It would take thousands of years for him to make a great discovery.
11:50When he tried to put willow bark on it
11:53He went and ate
11:54This bark, and suddenly...
11:55Note
11:57The pain subsides
11:58The pain is gone
11:59I'm comfortable
12:00Although before that, my dear, there was no connection between the two things
12:02I don't even understand why this happened.
12:04This is how the herbs felt their soothing effect on his body.
12:06So he adopted it as a dwelling place
12:07This also happened in Greek and Sumerian civilizations.
12:11At the same time, the Egyptians would discover the poppy plant.
12:14From which one of the most powerful painkillers known to mankind is extracted
12:17And that's what we started our episode with.
12:18Opium
12:19Opium, due to its uniqueness and distinctiveness as a painkiller
12:21He will be limited to priests, the desert, and warriors only.
12:24And its management is evident in more than one culture.
12:26Ancient Asian cultures, for example
12:28You can appreciate opium in medicine and religion
12:29The Somni people call it the plant of joy.
12:31And also ancient India and China
12:33They will use it to treat tooth and joint pain.
12:36They will turn it into fairy tales
12:37If he cut his eyelid, he would be deprived of the same sleep.
12:40He should remove it so he can keep his eyes open all the time.
12:41And after he cut off his eyelid, my dear, the fairy tale is told again.
12:45Opium grew from it to help humans sleep.
12:48Greek and Roman civilizations would prescribe opium for pain
12:51And with it plants from the Solanaceae family (Solanaceae)
12:54This family includes tomatoes, peppers, and eggplants.
12:57You could call it the mesquite family
12:59But be careful, they are poisonous plants.
13:01Like henbane, belladonna, mandrake, and incense
13:03Plants that produce atropine, solanine, and nicotine
13:06These are substances that relieve pain in small doses.
13:08But if taken in high doses, it can be fatal.
13:10Our instinct that drives us to relieve pain
13:12And the human being elaborated on how he widened the lemon a little
13:14This will lead us to learn about the most dangerous drugs.
13:17Drugs like cocaine, for example
13:18For example, ancient slates in South America
13:20They recognized it when they started chewing the berries of the coca plant.
13:23They also used it as a local anesthetic.
13:25My dear friend, I feel that the plant is a friend to the human market.
13:27He encourages you by giving you a drugged fruit.
13:29Healthy and beautiful things
13:30And then, from your side, this guy is trustworthy. Take this cocaine.
13:32Take this plant, you will take as much as you give, don't take
13:34Take it, come on, take it, come on, I'll come to you, whether by nature or by instinct.
13:37Take your stuff, take it, come on!
13:38And in Al-Azizi's history, there are no harsh solutions.
13:40The more the pain increased, the more severe it became.
13:42For example, Egyptians and Greeks will use electricity.
13:44To treat pain, the mericid places the affected limb.
13:47In a bowl with fish
13:48Nile perch or torpedo fish costume
13:50These are fish that generate electricity.
13:52You can use these chargers
13:53She will hunt and defend herself
13:54Don't go into the part where we're showing off; it'll be fine.
13:57Experience, my dear, reveals many things to us.
13:58However, sometimes they can be dangerous and their impact deadly.
14:01This led to the rise of many civilizations, such as the Romans and the Greeks.
14:03They sometimes neglect experimentation and focus on theorizing.
14:06Let's sit down and think about the theories that explain this pen.
14:09Let me tell you something, my dear, that you've never known before.
14:10A year, O Abu Ahmad
14:11Now you're going to tell the story of Hippocrates
14:13And the four liquids that he has
14:14I say, "Shut me up!"
14:15It was during the beginning, my dear, that you were tying me up like that
14:17Honestly, yes
14:18Hippocrates believed that there were four types of liquids.
14:20These are blood, phlegm, bile, and black bile.
14:23He was also saying that this pain was a result of this fluid imbalance.
14:28One of the students in Zagros also said
14:30He will see that the brain is the center of sensation and logic
14:32This man will be supported by other doctors with anatomical evidence.
14:35For example, you have the Roman physician Galen.
14:37This man will try to establish the concept of the central nervous system.
14:40And that the brain is the center of sensation
14:42And connected to the nerves of entertainment
14:44And that this pain is a warning signal from the body
14:46However, these looks are countless and widely accepted.
14:48And he rejected Aristotle's theory, which will prevail and sweep the world.
14:51These looks tell Abu Ahmed
14:52You say, my dear, that the heart is the center of sensory perception and the soul
14:56In parallel with these attempts
14:58You will find philosophies and beliefs
14:59It offers a way to deal with pain
15:01Medical services, for example
15:02He will recede in medieval Europe
15:03When I was helped by a religious idea, the summary of which is
15:05Pain is the human destiny.
15:07It is a form of spiritual suffering and divine justice.
15:10The solution to deal with your pain
15:18I was born deprived of any kind of painkillers
15:21But where are the spiritual interpretations at many times?
15:23You won't be stronger than the pain that controls you.
15:25Here, the Western monks will be present alongside their prayers.
15:28They are taking the place of the doctors, one by one.
15:30They translate ancient depictions of the origin and treatment of pain.
15:33They offer formulations that contain primarily opium.
15:36Usually, my dear, the history of science includes Europe and America only.
15:40But if we look in the East
15:41You will find a significant development in medicine among Muslims.
15:43One of the main reasons for the decline of middle classes in Europe
15:46Their entry into the scientific Renaissance
15:47They restored and translated the works of the philosophy of the stagnation.
15:50But this is a step that Muslims have already taken.
15:52European medicine will start to falter
15:53Until it opens in Salerno, Italy
15:55First medical school in the Middle Ages
15:57One of its pioneers was a doctor named Nicolo Dialo
16:00The one who published his book on medicines in the twelfth century
16:02He added to it the drug formulations created by Muslims.
16:04Especially Al-Kahali Ali bin Issa
16:06As for the term "Azizi," it was used to refer to an ophthalmologist.
16:08Ali ibn Isa was among the first people
16:10Those who suggested a very strange idea about our society
16:12The idea of anesthesia is the death of surgery.
16:14This is what I love
16:15He's the one who made the anesthesia
16:16If we look at the knowledge of Muslims
16:17We will find Ibn Sina in his book
16:19The law of medicine cites theories of the follicle
16:21Nus and Arsteh
16:21While Europe was advising submission to suffering
16:24I consider it an inevitable fate that we must live by
16:26The Canon of Medicine by Ibn Sina
16:27He will document, my dear, a very important idea
16:30Her name is Dee
16:30Listen to it
16:31Pain is a symptom, not a disease.
16:33Meaning
16:34Pain is the result of a cause we don't know.
16:37Which is the disease
16:37There's something wrong inside that needs fixing.
16:39There's no one who's sick and has a cough
16:41A cough is not a disease
16:42Coughing is a symptom
16:43A cough tells us what this is
16:45This man might have a cold.
16:46Or he might still have
16:47tuberculosis
16:47These are diseases
16:48What's discovered here?
16:49Pain Peshawar
16:50He tells us, "Look, everyone, at this point..."
16:52This is where the pain is.
16:53There's no need for a patient in pain to hear us
16:54Ibn Sina says that despite the pain
16:55Not a disease
16:56But the womb, it
16:57Of course, it's very important
16:58Especially if this disease
16:59It will take a long time to treat him.
17:00Or it might not be curable.
17:01He used to say, "If illness and pain are combined..."
17:03Start by relieving the pain.
17:04He will provide a treatment for each type of pain.
17:06Firstly, by preventing the cause of its occurrence
17:08Or with muscle relaxants or narcotics
17:09Like opium and anesthetic
17:10Anesthesia by reducing sensitivity
17:12In the painful organ
17:13Vomiting
17:14To cleanse the body
17:15Some of the substances that could be causing this pain
17:17Changing class-based treatments
17:18Like compresses and massage
17:20Walking can relax the muscles
17:22To relieve the pain
17:23All of this was said by Ibn Sina.
17:24We're reaching the seventeenth and eighteenth centuries, my dear.
17:27The old looks were the salvation of his ear
17:29And it's necessary to address this need.
17:30We, as a group, need a theoretical foundation.
17:32Overwhelmed by new discoveries
17:33In medicine and natural sciences
17:35European ideas about pain
17:36It will start to develop
17:37From demonic thoughts and evil spirits
17:39experimental scientific models
17:41It will receive an update
17:42The more knowledge increases
17:43About anatomy, physiology, and chemistry
17:45The French philosopher Rene de Cartes, for example
17:47He will present one of the oldest concepts
17:49Modern physiology
17:50The pain begins at the peripheral nerve endings.
17:53And it spreads to the rest of the brain
17:54When pain is stimulated in the brain
17:57He likened it to a thread
17:58Linked to a bell located in the brain
17:59The first thing you do is pull me towards love
18:01Tick
18:01The bell rings in the waves
18:02Tick tock tick tick tick tick tick
18:03You will feel pain
18:04Aiiiiiii
18:08Oh Abu Hamad, thank you so much for this wonderful trip!
18:10So you brought me and took me to ancient Egypt
18:12And then we went to Al-Sumaria
18:14And then we went to the seventeenth century and the eighteenth century
18:16And our religion was incomplete, from the Stone Age, the Chalk Age, and the Fossil Age.
18:19Oh Abu Hamad, I'm not someone who travels between eras
18:21I want to reach a solution
18:22Here, my dear, lies the problem
18:24All these developments in understanding pain that I'm telling you about
18:26These were developments in the study of pain, not in its treatment.
18:29We know and are coming from them
18:30Like after
18:31There is no primary source of pain relief we can rely on at this moment.
18:34non-opium
18:34We keep going around in circles and swinging back and forth again.
18:36From a very early time
18:37They knew the depth
18:38We are forced to rely on him
18:40Although it is a frightening, toxic, and infamous substance
18:42The harmful effects of opium have been known since the 14th century.
18:45Gecko Theodore's Herbal Science
18:47He will say in his book
18:48When we talk about this opium
18:49It is nothing but poison from a telescope
18:52Therefore, it can never be used.
18:54Except in cases of extreme necessity
18:55And he met him
18:56Ibn Sina would classify it as a deadly disease
18:58Despite being an excellent residence
19:00But in the 14th century
19:01Technology will emerge
19:02It will radically change medicine.
19:04Finally, the chemists
19:05They will be able to analyze natural products
19:07They analyze the criminal content.
19:09We will now find out that the elements we thought were naturalized
19:12Like water or air, for example
19:13It is free of various ingredients
19:15Secondly, my dear, this is inspiration and the idea is important.
19:17We can instead of giving opium
19:18In raw form
19:19Exalted is He above the creation of a prophet like that
19:20We sift through it and extract the active ingredient.
19:22Wendy is so clear
19:23Ski in its purest form
19:24We can then link the therapeutic effect
19:26In single entities
19:27Unify, O year
19:28This opium is made up of three pieces
19:29A piece you get addicted to
19:31A piece that will kill you
19:32And a piece that makes the pen more comfortable
19:33Let's dig inside it a bit
19:35We'll take out the part we don't like.
19:36And we get to the point that none of us like.
19:38In the year 1803
19:39A German pharmacist named Fredlix Toner
19:41He will be able to isolate himself from opium.
19:43The active ingredient inside
19:44This, my dear, is the first table in history.
19:46Therefore
19:47We can take the unit material
19:48We avoid the side effects of the other ingredients.
19:51It was the first time anyone had succeeded in isolating an active compound from us.
19:55My dear friend, you will notice that this is a very historical event in the history of medicine.
19:57Thank God we now have a painkiller bigger than opium.
19:59It will be launched in America and Germany under a trade name.
20:03morphine
20:04Yes, my dear, the one for critical moments.
20:07This name is derived from the name of the god of sleep.
20:09In Greek mythology, Morpheus
20:10You are thinking of Kater
20:11What did he tell you?
20:12We've learned how to cultivate and use opium.
20:14We solved the equation for effective and safe housing.
20:17And that's it, we named it morphine.
20:19Goods on Medicine
20:25From the pain caused by the cancer, which was in its final stages.
20:28He injects her with morphine under her skin.
20:30He discovers that its effect is three times faster and stronger.
20:32So here, my dear, morphine is transformed into syringes.
20:35Its use is increasing as a subcutaneous injection.
20:37Morphine is now readily available in pharmacies and prescribed for virtually anything.
20:40Cracks, fractures, toothache, your conscience is eating you up
20:43Take morphine for any pain
20:44To the point that in 1888
20:46It was 15% of all the rashes described in Boston
20:50Opioids in the Civil War
20:52He will use it to relieve the pain of the injured.
20:54They inject it into the soldiers
20:55Until reports emerged of an outbreak of morphine addiction.
20:58The goals of the warriors they learned
20:59They returned safe and sound after the war
21:00A man who returned, a national hero, full of his efforts
21:02And leave it tax-free
21:03And its absence is included
21:04The scientists will start telling you, "Hey everyone!"
21:05We need to think about another safe place to live.
21:07Especially since we are the Prophet's factory
21:09We now have new chemical technology
21:11What's left is for us to isolate the boat and bring everything separately.
21:13So why don't we fix it?
21:14Here they take one of the snot-blooded people to heat morphine with another substance.
21:17They do something called
21:18Then, my dear, the substance acetylmorphine is manufactured.
21:22And my dear, the person in charge of this subject...
21:24Although it is a non-addictive substance
21:26innocent formula
21:27Not like morphine, that monster, son of a...
21:30My dear friend, the blind have flooded the market with the new material.
21:33heroin
21:33Oh Abu Hamad, may God protect them
21:35What? What?
21:36What are you saying?
21:37Heroin, Abu Hamad
21:38Heroin?
21:39No, my dear, the heroin we know today
21:41That was the first one, coming out like a cough.
21:42Oh, and he was going down to the market.
21:44They were telling the children
21:45Heroin is derived from the German word
21:47heroin
21:48So, my dear, it goes down to the market and is described to both young and old without any explanation.
21:53Do you have a cold?
21:54Take heroin
21:54If you have a cough, take heroin.
21:56Any time he goes to the pharmacy, he clears his throat a bit and takes heroin
21:59Why, my dear, did I tell you that charitable organizations
22:00Which helped morphine addicts recover
22:03She was encouraging him with free samples of heroin.
22:12He was sending them heroin, my dear, through the best postal service.
22:15So they can stop taking morphine
22:16This is not the talk of the blue or the ignorant
22:17This was actually a marketing campaign for heroin.
22:20It is a cough medicine and an alternative
22:22For the morphine that you see, morphine
22:24My dear, I'm telling you something.
22:25David Nott, PhD, is a professor at an English university.
22:28Conduct a survey
22:29Ask all the drug scientists
22:30He asked them what the worst drug in the world was.
22:32In the world
22:33Number one
22:34heroin
22:34The worst drug in the world
22:35heroin
22:36Why was he invited?
22:38As a treatment for addiction
22:39He was dear to the children
22:40Opioids have become the drug of choice for pain relief.
22:44And improving mood
22:45To some extent, governments have seen the addiction and side effects.
22:48Respiratory collapse
22:50Which could lead to death
22:51And here, my dear, what is known as opioid phobia occurred.
22:53So, Abu Ahmed, what about us? Every time we get to the medicine...
22:55Humans become addicted to it
22:56Sometimes, my dear, your understanding
22:57Painkillers need to be understood
22:58How come your body isn't getting the benefits from it?
23:00But how does he get addicted to it?
23:01During it, my dear Al-Shahr
23:02There are two types of painkillers.
23:04And I am Abioun
23:04The fathers
23:05It must be taken under the supervision of a doctor.
23:07Because of her problem
23:07There are scent receptors present in our bodies.
23:09I ask her
23:10Ahmad's medicine and the body knew that it contained opium.
23:12The body, my dear, is full of opioid-like substances.
23:14Her name is Endorphins
23:15This, my dear, stretches your body
23:16And you're at the gym, for example
23:17So, the workers preferred to play with a man who didn't consider any pain.
23:19Hashish with intoxication
23:20In the name of God, what God wills
23:21Fahdi, an African, is galloping amidst the equipment.
23:23Captain Hosni returned home to his Lord
23:25The first thing you feel when you go is muscle pain
23:27There's no comfortable head position
23:28You have to be compatible
23:29When you take opioids from outside
23:31It binds to opioid receptors found in the body.
23:33It blocks pain signals
23:34What results do we get from this process?
23:36Dopamine
23:36The hormone associated with pleasure
23:38So there's no pain and no brain work
23:40This is a system for defining drugs.
23:41The problem is that the opioid receptors
23:43She adapts after a short period
23:44She anticipates new opiates
23:46Aren't you the one who used to give to us and send to us?
23:48If you don't bring her mouth, she'll make you suffer and give you withdrawal symptoms from your mother.
23:51The important thing is that the scientists said
23:52Erkin, put all these opiates aside.
23:54Let's see what else the times were relying on besides it.
23:56What did it really look like before this material?
23:58One of the Egyptians said that they used willow bark
24:02We analyze it and see that its material
24:03And indeed, Henry LeRox isolates a substance from willow bark.
24:06He named it after the German pharmacist Johann Bockner
24:081828 in Thalesin
24:10The Latin word means willow
24:12Other scientists convert it to thalassyl
24:14It is started as a pain reliever for rheumatism.
24:16nerve pain
24:17The problem, my dear, is that its taste is stagnant.
24:19American chemist Felix Hoffman was the father of Beedel
24:22Instead of trying to hide it, the man just brings up what's in his stomach with disgust.
24:24Fiji in the late 19th century, which he did
24:26This time it turns out to be a relatively safe accommodation.
24:29It is marketed by Bayer under the name Aspirin
24:32I know this is Abu Ahmed, the old green policeman.
24:34If it's addictive
24:36Honestly, my dear, if he were working you would know
24:37Over time we discovered that aspirin doesn't just relieve pain
24:40This also reduces problems associated with inflammation.
24:42Rheumatoid arthritis
24:44pericarditis
24:45and inflammation of the blood vessels
24:47He was so oblivious to his work and actions that even scientists didn't know how it worked.
24:49But this isn't working, so let it work, let it pass.
24:52Up until the twentieth century
24:54When scientists discover how aspirin works
24:56And they discover together that, unfortunately, nothing good lasts.
24:58This viewer said, "I have bad news for you."
25:00Aspirin and its related drugs remain deadly.
25:02When inflammation or cell damage occurs
25:03Important chemicals are released in the body
25:06Its name is prostaglandins
25:07When these binding substances bring the nerves closer together in order to stimulate them
25:09Here, the nerves send pain signals to the brain.
25:11So we'll feel the pain of aspirin, since it interrupts the production of these substances.
25:15Pay attention to the scientists who discovered this method of operation.
25:17They won the Nobel Prize in 1771
25:18Not the ones who discovered aspirin
25:19No, those who understood
25:20The problem with aspirin is that individuals in its use
25:22It can cause a false alarm in the intestines and brain.
25:24It can also lead to something called Reese's syndrome.
25:27Because these materials we talked about
25:28Two types of tasks
25:30The first type is inflammation, pain, and fever.
25:32The second type is that it will preserve the stomach lining.
25:35Why? We found ourselves in a situation where Hamda might be a metal worm.
25:38What prevents these acids from igniting in the stomach?
25:40Is this the faulty wall?
25:41This mucous membrane is caused by prostaglandins
25:43These substances also help the blood.
25:45He goes to the kidney in controlled quantities
25:46That's why
25:47People who started having kidney problems
25:48They can't give you aspirin.
25:49Aspirin essentially stops the second of these tasks.
25:51In helping the kidneys and stomach
25:53Amidst this sad discovery, we will find
25:55Aspirin has a very strong benefit besides pain relief.
25:57Which slows down the production of thromboxanes
25:59Which causes the accumulation of platelets that lead to blood clots.
26:02Aspirin reduces the risk of heart attacks by 44%
26:06Is it true, my dear, that it's only part of its security as a residence?
26:09Here, the aspirin started to accumulate in a certain area.
26:10But as a residence, people began to worry about it.
26:13He and the painkillers that work similarly to him began to lose some of their security.
26:15Prostaglandins, which we call incidides
26:17Non-steroids, anti-information drugs
26:20Like aspirin or aspocid
26:21Ibuprofen, also known as Brufen or Advine
26:23Diclofenac, like Voltaren
26:25Ketrolac, like Ketolac
26:26In dozens of types of incidence
26:28They are all effective, relatively safe, and reliable.
26:30Difficult to jump
26:31But, my dear, to the best of our knowledge, it is not safe for patients with digestive and speech disorders.
26:36Come, my dear, I'll take you back to the late twentieth century.
26:39When it will cover up the effort of aspirin, another painkiller with side effects will be used, he said.
26:42We'll connect him by chance.
26:44An effective and safe pain reliever for the stomach, suitable for all family members.
26:48breastfeeding mothers, pregnant women, and children
26:50Second one, Abu Hamad, you're saying it's safe?
26:52We'll include something in this topic.
26:53And it is, my dear, paracetamol
26:55Okay, Abu Hamad, I know what will happen next.
26:57You'll tell me then that he falls on the teeth and drops the jujube of my quail
27:00And it makes me a watercress addict
27:02Isn't that what you want to tell him?
27:03Please, my dear, use your imagination a little more.
27:05You probably already know what paracetamol is by its brand name.
27:08Pendulum or other types
27:09Like paracetamol, Tylenol, and their companions
27:11All countries, my dear
27:12Fristamol
27:13The story of paracetamol begins by chance.
27:15A student researcher is working on a treatment for intestinal worms.
27:17Then a substance called stannyl alcohol was used to seal it.
27:20The material, my dear, didn't reach two issues.
27:22But the patient who had a fever
27:23His fever went down
27:24Sima, I'm leaving, my dear.
27:25History Comedy
27:26Paracetamol, the world's largest drug, has similar names.
27:28In 1988
27:29Scientists then derived another compound from it.
27:32His name is Feinstein
27:33Our sisters at the College of Siddala are forbidden from swearing.
27:34After that, paracetamol will replace it.
27:37What's in where? In Panadol.
27:38We can confidently say that Panadol has solved the complex equation of effectiveness.
27:41And at the same time, God willing, in front of
27:43As long as you take reasonable doses
27:45You are taking more than 4000 milligrams daily.
27:47For example, Panadol Advance 500 mg
27:49So you are in any case
27:50Don't take more than 8 heads per day
27:52Paracetamol has what is called
27:53After a certain dose, higher doses do not add
27:56No additional pain relief
27:58At a certain dose, I won't do more than what he already did.
28:00However, some medications make the effect of Panadol faster.
28:02For example, if they combine it with caffeine
28:04Like Panadol Exra
28:05Or Panadol Cold & Flu
28:07Caffeine doesn't just make you feel good
28:08No! This also increases the absorption of paracetamol.
28:11Therefore, the effect is faster.
28:12So, how does this guy, the one who solves this difficult equation, actually work?
28:15You didn't tell us how aspirin works.
28:17Say, "Aren't you the Opera of Science?"
28:18Hey, dear ones, nobody knows how at work
28:20Paracetamol breaks down into active compounds in your body within a blink of an eye.
28:24Some of them reduce prestaglandins by a small percentage.
28:26Some of them block pain signals from reaching the brain.
28:29They carry this successfully
28:30How can you ask me? I'll tell you I don't know, ask Saeed Alha.
28:32I tell you with pleasure, we don't know because it's our turn
28:34But paracetamol is certainly the safest pain reliever.
28:37Favor and enjoyment without maturity
28:39It is also effective in reducing fever.
28:41In many healthcare cases
28:43It reached me during the COVID time if you were treating yourself at home
28:46It doesn't cause problems during pregnancy or breastfeeding.
28:48And God willing, there will be no problems with the packaging.
28:50And before you, sir? Even the children
28:52Paracetamol, like Stal for example, is fine for them.
28:54The only situation where you shouldn't take paracetamol, my dear son
28:56If you, God forbid, have liver disease
28:58It is true that paracetamol is broken down in the liver into non-toxic substances.
29:01But if the dose is too high, it could cause problems.
29:04That's how it is, my dear, to protect ourselves from any legal issues.
29:06You should consult a doctor.
29:08I am fair and I shake and say
29:09This one does this, and this one doesn't.
29:11And I'm telling you, you should consult a doctor in the end.
29:13No one can touch anything on me
29:15So far, my dear, the pain is not acknowledged.
29:17As a disease in itself
29:18This is still a point of contention among doctors, especially regarding chronic conditions.
29:21But pain has always been the greatest symptom in medicine.
29:24Not only that, my dear, because it accompanies most diseases
29:26But that's the main reason that drives the patient to seek consultation.
29:29And the doctors are forced to get up and look for treatments.
29:32And then this pain alerted us that there was a certain mistake here.
29:34The pain loses its power and turns into a burden
29:36It's meaningless, just like when the pain continues.
29:38It turns into chronic pain
29:40Why are you torturing me, Aster?
29:41Dr. Sean Bonica, founder of pain medicine
29:43He says that when pain treatment is accompanied
29:44It begins to lose its useful purpose
29:46It transforms into a physically and psychologically destructive force.
29:49Hey, you're supposed to tell me that something's wrong here.
29:51But why? There must be something wrong.
29:53But you still hurt me
29:53This makes painkillers one of the most important inventions in human history.
29:56The first line of defense in most doctors' prescriptions for most diseases
30:00The history of the discovery of painkillers is not just a story about the development of science.
30:02But about man himself and his attempt to overcome
30:05About the biggest enemy of his life
30:07Greatest enemy and greatest friend
30:08Pain has a long, inspiring, and painful history in many stages.
30:11But thanks to the accumulation of knowledge and research, the centuries continued by chance and targeted research.
30:16We still have painkillers here that we can use in our daily lives.
30:18My dear Betty, in the end you can listen to me until the end of the episode without a headache
30:21Because if you get a headache, you can't take a safe painkiller without becoming addicted to anything.
30:25But my dear, please be careful, I'm very sorry.
30:27Al-Daheeh episodes are now available; an effective and fast treatment.
30:30You never know what might happen in the end? You might even become addicted to Al-Daheeh.
30:32The effects and influence of opium on you may become...
30:35Honestly, I wish it were so, because I'd be the one who benefits.
30:38Be aware, my dear, that you don't know about this subject.
30:39But I think your body has special receptors for the nerd
30:41Al-Dahih Opioni
30:42So, the opposite remains from the episode that you were distracted and worried about, and it's coming down now.
30:44It's blocked, and we're watching. Subscribe to the channel.
30:46You know, my dear, I'm very afraid of Panadol.