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00:00Casey, you're here again, what's wrong?
00:14It's just, it's my back, it's getting worse, and now I've got these headaches, it's throbbing
00:20in my ears and nothing's drowning it out.
00:22You need a hospital.
00:23I need a hospital, I need insurance, I need a lot of things.
00:26Okay, wait here Casey, I'll find a doctor.
00:30This morning's numbers, Mr. Bell.
00:39Ranger, my name is Joseph.
00:42I keep telling you that.
00:43These numbers are good.
00:45I've got the liver of a 22-year-old, kidneys tracking at 25.
00:49I should make a post for socials.
00:51Tell Kristen to write it for scrubs.
00:52Number 92, please.
00:54The doctor's ready to see you.
00:56Number 92.
00:57Do you want me to confirm your interview at 1100?
00:59I doubt the doctor would call it an interview, I hear the man's got an ego.
01:03But, confirm.
01:04Can you get the car ready and come back?
01:06Yes, sir.
01:07I'm so sorry, we're short staffed, Casey.
01:09Listen, you could be having a stroke, an aneurysm, a hemorrhage.
01:12The point is, I don't know, I'm just a volunteer.
01:14They can't turn you away from an ER.
01:16You need tests, imaging, an MRI probably.
01:19This is what I need and this is what I can afford, man.
01:21I know about a place.
01:23That girl I used to see at Pitt, she works there.
01:25Insurance, your ability to pay, it's not always their first concern.
01:28Well, what's the place?
01:30It's a second right.
01:32Car's ready, sir.
01:33Remind me what I'm putting into the GPS.
01:36It's called the Holmes Clinic.
01:38What kind of name is Ranger?
01:45My father wanted me to be an army ranger.
01:48A ranger named Ranger.
01:49So did you make the cuts?
01:51Three tours.
01:53And you?
01:54Where'd you get your train?
01:55The high-down youth offender institution.
01:59More of an informal program, really.
02:01Aging is a disease.
02:04Do you agree, Dr. Watson?
02:05I agree that it sounds catchy.
02:07It's more than that.
02:08This is critical work.
02:10The human lifespan is about to expand 50 or 60 years.
02:15And it's right around the corner.
02:17I haven't seen evidence of that.
02:19But yes, if you want to put crazy amounts of money into your health,
02:22personal chef, IV drips on call, hyperbaric chamber, red light therapy,
02:26then yes, most of the time, you can squeeze out a couple extra years.
02:29We're on the same page there.
02:30No, we're not.
02:31You've got to expand your mind, brother.
02:32Because I'm going to be the first man to climb K2 at 100 years old.
02:37I'm going to father a child at 115.
02:39Well, I can see why that would be critical work for you, brother.
02:44But I don't see the bigger picture.
02:46Somebody's got to do it first.
02:48And then, eventually, everybody can do it.
02:52Look at these numbers.
02:53Just look and then tell me I'm crazy.
02:57I am the bellwether for humanity's future.
03:01Maria?
03:02Hey, thank you so much for doing this.
03:04Yeah, of course.
03:07You're Casey, right?
03:08Yeah, Casey's inked.
03:10My name's Sasha Lubbock.
03:11I'm a rheumatologist immunologist at the Holmes Clinic.
03:13This is my colleague, Ingrid Darien.
03:14She specializes in neurology.
03:16Your symptoms are concerning for elevated intracranial pressure.
03:19We'll get you straight in for an MRI.
03:20But I can't afford an MRI.
03:22I keep saying that.
03:22Our clinic works differently.
03:24If you can't meet the cost, your imaging is covered by our operating grant.
03:27Liver of a 22-year-old.
03:31Well, you might want to check and see if he wants it back.
03:33Ha ha!
03:34You know what I mean.
03:36Look.
03:39I'd like you to come aboard the team.
03:41Okay?
03:41You can be the official genetics consultant for anti-aging generation.
03:48Anti-aging generation.
03:50Meaning you.
03:51AAG's a company.
03:54It's a movement, too.
03:56Believe what you like.
03:57But this could mean the world to your clinic.
04:00And the funding I'm able to provide is virtually unlimited.
04:07Listen, congratulations on your liver.
04:12But I'm not a concierge doctor.
04:17You're an MRI.
04:18I had five of these in the same year.
04:20Five MRIs?
04:22Were you dying?
04:23I pitched for Penn State.
04:25I got drafted by the Brewers out of high school, but I picked college ball.
04:29And then I shredded my labrum and lost my scholarship.
04:34I guess here we are.
04:35The only thing I really knew how to do was throw a baseball, and now I can't even do that.
04:44We're done here.
04:46Perhaps we'll meet again, young Ranger.
04:48I bet.
04:49Ranger.
04:50Now.
04:51I hate to have to tell you this, but you have a large growth in your spinal cord.
04:58It's called an ependymoma.
05:00Is that a tumor?
05:03Yes.
05:05The safest and most effective approach is surgical removal.
05:09But fortunately, we have an excellent team here.
05:11I'm going to refer you to Dr. Mary Morse.
05:13It was fine two months ago.
05:15I'm healthy.
05:17What happened?
05:18I mean...
05:18I'm sorry, Casey.
05:20It's a lot to take in.
05:21John, I need to see you.
05:27Yes.
05:28Excuse me.
05:28One moment, please.
05:33I hate this as much as you do, but I have had, I don't know, 12 calls from Billing.
05:38We need to do a breakdown of care with your patient.
05:42He's financially responsible.
05:43Oh, Casey is a patient of the homeschooling.
05:45He's covered by our operating grant.
05:47Your operating grant is not operational.
05:50Word came in a few hours ago, the homes clinic is denying Casey's care.
05:54What?
05:55I can't see.
05:57I'll get by this.
05:58I can't see.
05:59I can't see.
06:00What's happening?
06:01Too much pressure on your optic nerve.
06:02I need to do an emergency lumbar puncture.
06:03He could herniate.
06:04Administer mannitol and steroids.
06:06Will I be able to see again?
06:07If we move faster.
06:07John, he's financially responsible.
06:09He needs to consent to treatment.
06:10What?
06:10What?
06:11I have to pay?
06:11You said I was covered.
06:12You promised me.
06:13You will be covered, Casey.
06:14I'll take care of this.
06:15That's my patient.
06:15Take care of him.
06:16I will pay myself if I have to.
06:20Why are my patients being denied care?
06:24They're not your patients until they can be responsible for their own treatment.
06:28We don't worry about that here.
06:29Why are you whispering?
06:30I'm at my club.
06:31We reject idle conversation.
06:33This is the 21st century, Watson.
06:35No one seeking treatment is free from worry.
06:39There's a 23-year-old that's dying in this hospital.
06:4123-year-olds are dying all over the world.
06:43It's rare, I'll grant you.
06:46But there are 8 billion people.
06:47I'm treating Casey Zink.
06:49Stop messing with my funding.
06:50It's not your funding.
06:52It flows to you courtesy of the Holmes family.
06:56I am the only living Holmes.
06:57Therefore, I offered you options, Watson.
07:00I encouraged you to resume aggressive research.
07:04And all you had to do was sign a couple of pieces of paper.
07:07No, I do this.
07:08We do this.
07:09To help people.
07:11My research is never going to belong to your company.
07:13Right.
07:14So that 23-year-old, you said his name was Casey.
07:18He'll just have to pay for the treatment you're giving him.
07:21I sleep 10 hours a night, Dr. Watson.
07:36I don't wake up for just anyone.
07:39Ranger said you had some questions.
07:43So when you said unlimited funding, what does that mean?
07:49It means exactly that.
07:52It means you please me, and I'll find a way to please you.
07:56I have a patient that needs some help.
07:58If you will pay for his treatment, all of his treatment,
08:02I'll work with you for a month, and we can revisit after that.
08:04One patient.
08:07I thought you'd cost more.
08:09One patient for one month.
08:12A month.
08:14Sounds good.
08:16Welcome to the team, Dr. Watson.
08:19Do we have a sugar daddy now?
08:24No, we do not have a sugar daddy.
08:27I'm embarrassed to even know what that means.
08:29It just sounds like you're getting in bed with the rich guys
08:31so that we can pay our bills, and that's called having a sugar daddy.
08:34No, no.
08:35We're just working through this situation with Mycroft Holmes.
08:39He didn't fund this clinic, so he can't control who we see for him.
08:42In the meantime, I've found alternative ways to treat our patients.
08:46Sugar daddy.
08:46I'm not asking you to provide concierge services for Joseph's Bell.
08:51I'm going to take that bullet.
08:53All you have to do is prep Casey's, Inc. for surgery
08:55and find out how a 23-year-old came down with a spinal tumor.
08:59Dr. Croft, I'll go with you.
09:03The Bell is interested in his work.
09:04Because of course you are.
09:06Okay, Joseph Bell is a lot, a whole lot, but longevity is a legitimate field of study.
09:11All right, fine.
09:11Come with me.
09:12Ingrid, prep Casey for surgery with Dr. Morstan and bring back that tumor for analysis.
09:17Sasha and Stevens, get those cancer cells under a microscope.
09:20I'll be in Sweekly Heights.
09:22Take in one for the team.
09:25Good luck with your sugar daddy, Watson.
09:28Do you want to go over the risks again?
09:30I'm 23.
09:32I shouldn't have a tumor.
09:34It's not fair.
09:35No one's saying it is.
09:37But why am I even here?
09:38All those people, that free clinic, they all need help.
09:42So why is it me?
09:43Why am I getting the red carpet?
09:46Now you don't have to answer.
09:47I haven't walked off the ledge yet.
09:49One day you wake up and you've been sick long enough and you've been broke long enough and
09:59then suddenly people won't look at you anymore and they can't look at you because the questions
10:08you make them ask are just too big to answer.
10:16I probably got three years before that because you can still look at me.
10:21You can picture someone who doesn't live in their car.
10:24And that's, that's why I'm here.
10:29That's not fair either.
10:30But you are here.
10:36And there's a surgeon waiting.
10:51Gear up, boys.
10:52Need you in the logo for socials.
10:54Um, I'm already dressed, but thank you.
10:57All right, well at least hold a water bottle or something.
11:00And what's your handle?
11:00I want to tag you in the post.
11:02I don't have a handle.
11:04You're going to need a handle, buddy.
11:18And I was thinking you could, uh, hold up your book.
11:21You know about my book?
11:23You write for your genotype.
11:24Yeah, my chef and I reviewed it together.
11:25All right, so we are announcing you as the newest member of the team.
11:30But first, do your thing.
11:32Read me.
11:33Read you?
11:35We need to do our own genetic tests.
11:37That's going to take some time.
11:38Yeah, I'm not talking about the DNA test.
11:39I'm talking about the magic trick.
11:41Read my face.
11:43Tell me my genetic destiny.
11:46It's not that simple.
11:48Well, give me something.
11:52Okay.
11:52Okay.
11:55Increased nasal height due to inherited material in your ATF3 genome region.
12:00Prominent brow, mouth, occipital button.
12:03I say you're about 4% Neanderthal.
12:05No!
12:07Not the Neanderthal thing.
12:09Again.
12:09Well, it's actually very useful information.
12:11You're susceptible to type 2 diabetes and Crohn's disease.
12:14I'm not saying you're wrong.
12:15I'm just saying that that word, Neanderthal, cannot be associated with me or with AAG.
12:20Yes, but Neanderthal is actually a misunderstood term.
12:22It doesn't matter if it's true, man.
12:25It matters what people think.
12:27So, don't mention my name in connection with that word.
12:30It's all good.
12:35Let's get this post up.
12:40AAG on 3.
12:421, 2, 3.
12:43AAG!
12:44Had a blast talking genetics with John Watson and Adams Croft, the newest doctors on the
12:50AAG team.
12:52Who is Adams Croft?
12:54Joseph Bell must have gotten the two of you mixed up, adding an S to Adams name.
12:57He's going to be so pissed.
12:58Why?
12:58It's a typo.
12:59It's a typo, but it's also right.
13:02Adams' real name, it's Adams.
13:06Somewhere along the way, my brother decided to pretend he's not a New England prep school
13:09kid.
13:10I also was born Adam Croft.
13:11Stevens and Adams, extra S's for everybody.
13:15Don't say anything.
13:16He's sensitive.
13:18Actually, can you take a shift?
13:19I'm going cross-eyed.
13:22Oh, I got a text from Ray.
13:23She wants us all to get together for drinks tomorrow.
13:24I have training after work.
13:26A hospice, remember?
13:28So you're going ahead with that?
13:29It'll be good for me.
13:31Get out of my own head.
13:32Look at you.
13:33Volunteer work, sit in the morning sun.
13:35Cold plunges.
13:36You're really going after it.
13:38Treating whatever's going on with you.
13:39You mean major depressive disorder?
13:41Well, according to Ingrid.
13:43I respect Ingrid.
13:45We all respect Ingrid, but can we agree that she's maybe not the world's leading expert
13:49in mental health?
13:50I think it's great what you're doing, but we are, you know, doctors.
14:02If you're going to treat a diagnosis, shouldn't you have an actual diagnosis?
14:06I can get you names, qualified psychiatrists, and maybe you could even talk to one of them.
14:10Right.
14:11Therapy.
14:12Yeah, maybe.
14:18That's strange.
14:19What?
14:20Casey's cancer cells.
14:21They should have died by now, but look.
14:26They're replicating.
14:27Barrier incision complete.
14:32Almost there.
14:35Margins clear laterally.
14:38Mobilizing the inferior aspect of the tumor.
14:41Tumor's soft.
14:43Planes holding.
14:46Suction.
14:48Opinion, Dr. Darian.
14:49Is it a feeder vessel?
14:51Planes not clear.
14:52More suction.
14:53We're into normal cord.
14:57I'm backing off.
15:02Having a hard time in here.
15:04Dr. Darian, what are you seeing?
15:07The tumor's dorsal edge looks fused.
15:09Agree.
15:14I can't risk permanent damage.
15:17I'm not going to trace it.
15:20We're calling it subtotal resection.
15:23She'd still relieve Casey of his symptoms.
15:25But he'll need more treatment.
15:26Not the one I was hoping for.
15:32We debated whether to call you here.
15:34I was just reviewing Joseph Bell's stool log.
15:37You can call me anytime.
15:38We've been following Adam's socials.
15:40Seems like Bell's a handful.
15:42Too much money to leave supplements.
15:44Anyway, let's talk about our real patient.
15:46Is Casey awake?
15:47Still in recovery.
15:48He doesn't know his surgery failed.
15:50It's not even his biggest problem.
15:51We've been analyzing the cells from the tumor biopsy.
15:54We just finished the RNA sequencing.
15:56Is this the right sample?
15:57We quadruple checked.
15:58Look at the end of the RNA sequence.
16:00Should have a poly-A tail.
16:01A short string of A's.
16:02There's some G's too.
16:03Not to mention it's long.
16:04Too long.
16:05A tail like this couldn't occur naturally.
16:07Which suggests genetic modification.
16:09Somebody mess with Casey's genes.
16:11This is genetic tinkering.
16:14Casey's cancer was man-made.
16:15He's sick because someone made him sick.
16:21I had a mate who died like that.
16:25Cancer.
16:27Old Tom Dinkle.
16:29Smoker from the age of 10.
16:31But that's not what you mean when you say man-made, is it?
16:33Cancer can come from genetic predisposition, exposure to carcinogens, a lifetime of bad habits.
16:40This is different.
16:41If I sequence a typical cancer cell, this genetics would be random.
16:47A shuffled card deck.
16:49Casey's cancer isn't shuffled.
16:52It's uniform.
16:52It's engineered.
16:54Meaning?
16:55Meaning his disease is the result of a deliberate genetic modification.
16:59What's fascinating and frankly nightmare is that these cells seem to be, I don't know, unkillable.
17:09Well, we treated these cells with a full round of chemo.
17:12Zero effect.
17:14Like a bad guy from a horror movie.
17:17So I still have cancer.
17:19I can't move any of my limbs and you're saying someone did this to me?
17:22Well, I can't speak to the larger issues.
17:25But as for the paralysis, you're still in the window of post-surgery swelling.
17:28Is this Aaron Brockovich stuff?
17:30Did I live under the wrong power line, sip the wrong water?
17:33No, this is something else.
17:34Gene editing.
17:35Somebody hacked your genome and gave you a form of cancer that, as far as we can tell,
17:40isn't pervious to existing treatment.
17:43What?
17:44How?
17:45That's what we're hoping you can help us with.
17:47If you haven't voluntarily submitted to a procedure that would alter your genes...
17:51You mean did I volunteer to get immortal cancer?
17:55No, of course I didn't.
17:57Then someone did this without you knowing about it.
17:58Have you had any injections recently?
18:01A blood draw?
18:01Any medical procedure could give us a handhold.
18:03I don't even know where to start with all that.
18:06I'm basically a human guinea pig.
18:08What does that mean?
18:10After I lost my scholarship, I had two different call center jobs that got sent overseas.
18:14Data entry that lasts as long as it lasts.
18:16Server gigs that go away when the restaurant closes.
18:19And in between all that, I sign up for studies.
18:22Medical trials.
18:23Sleep stuff.
18:24Consumer products.
18:25Anything that pays the bills.
18:27How many studies?
18:28I don't know.
18:29A few.
18:30A year for a few years.
18:31Any of these studies involve gene editing?
18:34Not that they said.
18:36Not that I remember.
18:38But I don't always read the terms and conditions.
18:42Remind me never to sign another release form again.
18:45You can't just slip man-made cancer into the fine print.
18:47I mean, I don't read those things.
18:49Does anyone?
18:49Casey's tested food dyes, hair products.
18:52He did a sleep deprivation study at TIT.
18:54Man, this is bleak.
18:57Not all of us have rich parents.
19:00Nice jacket, by the way.
19:01They're comfortable.
19:02I got one for everyone.
19:03I don't wear my boss's merch, but thanks.
19:05Come on, leave Adams alone.
19:07Let's just focus on the studies.
19:08Adams?
19:11Any trial at a university or a big company would be regulated.
19:15But Casey said that he participated in some privately funded studies.
19:20Let's start there.
19:21How?
19:22Where would he keep his records?
19:24He has a car, right?
19:25He said it's parked in his friend's driveway.
19:27He had her move it when he came here so it won't get towed.
19:29Okay, go there and see what you can find.
19:31Crofts, sit with Casey.
19:33When he wakes up, see if you can get a more detailed history.
19:36Is that our Neanderthal sugar daddy?
19:38I'm pretty sure we're contractually forbidden from saying that word.
19:41Is that our secretly Neanderthal sugar daddy?
19:43I wish it was our other sugar daddy.
19:47Punctuality, Dr. Watson.
19:49These meetings will be better for both of us if we keep to a schedule.
19:53We don't need to check in every day.
19:55In fact, we don't need to check in at all.
19:57Your brother endowed this clinic to give me the freedom to run things my way.
20:00He did that with money from my company.
20:03We both know that you founded this company based on his ideas.
20:05His idea would have died on the vine if not for me.
20:09You obviously have issues with your brother.
20:11I don't see why my patient should be in the middle of that.
20:13Had issues, Watson.
20:15One can hardly have issues with a dead man.
20:18This doesn't have to be adversarial.
20:20I'm not here to close your doors.
20:22No, but you're trying to get some kind of revenge on your brother.
20:25And I'm never going to go along with that.
20:27We were never particularly close, you know.
20:29I always fancied him a loner and then you came along.
20:32You disproved my whole theory.
20:36Just had no interest in me.
20:41So, we will have our daily meeting and our mutually beneficial partnership,
20:45even if there are growing pains along the way.
20:47Casey tried to make it like home.
21:00He probably thought his back pain came from sleeping in the car.
21:03Take the back seat.
21:05I got the trunk.
21:05Can I ask you something?
21:16Favor, I guess?
21:18I'm listening.
21:19Stevens believes you.
21:20He may have depression.
21:21I'm not a psychiatrist.
21:23He asked me what I thought.
21:24I told him.
21:25That's the thing.
21:26He thinks you're right.
21:26But he won't go see someone who could actually diagnose him.
21:30That doesn't make sense.
21:31Correct.
21:31He'll sit in the morning light.
21:33He signed up to sit with hospice patients, but every time I bring up therapy, he changes
21:36the subject.
21:37I'm his girlfriend.
21:39I don't want to be his mom.
21:40And I thought maybe you could give the old college try.
21:43Oh, so I get to be his mom?
21:44It's different with you two.
21:46Y'all have something now.
21:48We have something.
21:50I'm not jealous.
21:52I was just wondering if you'll talk to him.
21:57Hey, come look at this.
21:58It's a pay stub, sign agreements, Casey kept records.
22:05Have you heard of this place?
22:07Primal Biotech?
22:08What's that?
22:09This is weird.
22:11Primal Biotech website is full of broken links.
22:14It's pretty much defunct, as far as I can tell.
22:16Their non-disclosure agreement is state-of-the-art.
22:18I emailed Lauren.
22:19She says it's unusually dense.
22:20It's way beyond the standard boilerplate.
22:23Kind of like someone had something to hide.
22:25What is this place?
22:26Casey remembers two visits to the same temp office.
22:30First was a blood draw, and three weeks later, an IV drip.
22:34The lab tech said it was a vitamin supplement tailored to his genome.
22:37A global search of Casey's email shows that Primal Biotech sent 57 follow-up questionnaires
22:42over a span of two months.
22:43The email reply just bounced back now.
22:45This is a shell company.
22:46They conducted one study and then vanished without a trace.
22:49He did leave a trace.
22:50I was there the whole time.
22:52It takes real arrogance to sign your work.
22:54What are you talking about, Watson?
22:55I'm talking about Casey's genome.
22:57Take a look and see what's coded on the RNA tail sequence.
23:01AIG.
23:02Anti-aging generation.
23:04The company that got Casey sick is owned by Joseph Bell.
23:08So one man comes to us for treatment, desperate for whatever help he can get.
23:19Another hires us on, but just as the latest in an endless list of luxury purchases.
23:24And you're saying, Gov, then they're connected.
23:28The case is sick because of Joseph Bell.
23:30Remember what Sherlock said.
23:33The universe is rarely so lazy.
23:36The clinic is the spoke in a giant wheel made of medical science and cutting-edge innovation.
23:43Now, of course, both of them wound up here.
23:45I mean, it was the only place they could wind up.
23:48Sasha, tell us what happened.
23:49Casey signed up for a study.
23:50Joseph's people injected him with whatever, an editing agent that turned on a specific gene.
23:55One meant to boost longevity and squeeze out a few more years.
23:58They didn't set out to give him cancer.
24:00It's just how it turned out.
24:03What happens now?
24:04I assume Casey can sue Joseph if he wants to.
24:07If he can find a lawyer and crack those terms and conditions.
24:09Oh, no contract in the world can cover death by accidental cancer.
24:13Yeah, but does it matter?
24:15Casey's dying.
24:16Money can't help with that.
24:17Whatever it was that Joseph gave Casey, we need it.
24:21We need to find it, and we need to study it.
24:24If this cancer can be caused by genetic manipulation, then we can work with that.
24:28If Bell even still has the stuff.
24:30Joseph Bell wants to live forever.
24:32If he can't have that, he'll settle for 20 extra years.
24:35Somewhere inside that compound, we will find what we're looking for.
24:38So we just walk inside Bell's estate, poke around, and without drawing suspicion?
24:43No.
24:44He's going to invite us inside.
24:46As soon as I put up this post message, I'm sorry, when am I supposed to call one of these things?
24:51You're signing up to social media.
24:53Just for now.
24:55So interesting to learn that at the Joseph Bell AAG is parked in Neanderthal.
25:00These Titans of the Tundra are the ultimate survivors.
25:03Go, Neanderthals.
25:04At the Joseph Bell AAG, repping the smooth-brained Titans of the Tundra.
25:08Hey, guys.
25:09Neanderthals brought me at the Joseph Bell AAG.
25:12That's an A-plus on a thumbs-up test.
25:20That's a good sign, right?
25:22It's a great sign.
25:24It means your swelling is down.
25:25For now, rest will continue to monitor your progress, but I'm optimistic you will regain full function.
25:32So lasting paralysis is off the table?
25:34It is.
25:36I'm really happy for you, Casey.
25:38Just in time to die, though, right?
25:40We're working on a treatment, Casey.
25:42We haven't given up.
25:43Okay, well, what if this doesn't work out?
25:45Right?
25:45How much do I have coming to me?
25:47I mean, if this study kills me at 23, at least I'll be rich, right?
25:50You can't be rich and also dead.
25:57I mean, come on.
25:58Can I at least pick?
26:00I wish it worked out that way.
26:02I really do.
26:03What the hay, boys?
26:09Half the internet's calling me a caveman.
26:10Caveman?
26:11That's actually not accurate.
26:12Well, like I said, accurate don't matter when the whole world is clowning you.
26:16You're right.
26:17It's my bad.
26:17I get lost in my head sometimes.
26:20I'll delete the post.
26:21Well, it's already been re-shared 60,000 times.
26:25How about we give the world something else to talk about?
26:29Telomere lengthening.
26:30It's where we tweak the ends of your chromosomes.
26:32Now, if you want to add some extra years to your lifespan, that's the real.
26:38I'm down.
26:39Are you sure?
26:40Because this is gene editing work.
26:42Am I sure?
26:44Yeah.
26:45I'm not just vitamins and cold plunges.
26:47I'm trying to get revolutionary.
26:49Safe and legal just means slow and boring.
26:52So LFG, buddy.
26:53Jack me up.
26:55If you dare.
26:56Joseph, after your blood draw, we should replenish your fluids with an IV.
26:59I brought a baseline solution, but I assume you have your own.
27:03Yeah, I don't put anything baseline in my body.
27:05Not when I have a medical supply room tailored to my exact genome.
27:10I mean, why should you?
27:11I mean, screw it for you.
27:12Exactly.
27:13Exactly, John.
27:14Yeah, yeah.
27:15I agree.
27:16Hey, Ranger, why don't you show Dr. Croft the inner sanctum?
27:18Mr. Bell calls this a longevity bunker.
27:26Mr. Bell, you can't call him Joseph.
27:29I'm pretty sure he likes Mr. Bell.
27:37Okay.
27:37Okay.
27:48Mr. Bell, you think about something probably?
27:53Mr. Bell, I guess it's a...
27:55Mr. Bell, I'm not sure if you're looking after someone at that point.
28:03Nursing school.
28:04Tell me about that.
28:05What's that like?
28:06Mr. Bell, you're doing your research.
28:08Mr. Bell, it's the kind of work.
28:09It has a ceiling, right?
28:10You've turned it into something else.
28:12Hmm.
28:13Mr. Bell, you know, I was a medic in my unit.
28:16I'd say that puts you ahead of the gun.
28:17Oh, yeah?
28:18Yeah.
28:19Figured as much.
28:20Swing down to the clinic, son, so I'm without him.
28:23Absolutely, I'll do that.
28:24There we are.
28:28Poison apple.
28:30Casey's illness began when the contents of this vial got into a system.
28:35We do our jobs right, this is what can save them.
28:37You want to make a small interferon RNA treatment from one sample?
28:41We can do it.
28:42We can make an off switch designed specifically to target Casey's cancer.
28:46I get it.
28:46S-I-R-N-A is the future of medicine, but this hasn't been widely tested.
28:50There are a million variables.
28:51You're wondering what we do if it doesn't work.
28:53I'm asking a question.
28:54If it doesn't work, then he dies, obviously.
28:58That's happening anyway.
29:00Casey's cancer comes from a single gene manipulation.
29:03This is the perfect test case for the treatment.
29:06Can anyone tell me why?
29:07S-I-R-N-A gets inside the cancer cells, sends them a message to self-destruct.
29:10It's kind of poetic if you think about it.
29:13How do you kill an immortal cancer?
29:14You make it kill itself.
29:16Watson, I ran the samples you took from Joseph Bell.
29:20They tested them against the markers you requested.
29:22And?
29:22I think you have this backwards.
29:30You're not really on call to show up wherever you want.
29:33Shh, quiet, please.
29:35My patient's asleep.
29:36This is Casey Zink.
29:38You don't know him, but he has a tumor in his spine.
29:42That's terrible.
29:43He's so young.
29:44He signed up for a trial with a company called Primal Biotech.
29:48They put something in his IV.
29:49It was a genome tweakment to extend the human lifespan.
29:55Instead, he got cancer.
29:57You did it, Joseph.
29:59You did it.
29:59I mean, you created something that just won't die.
30:02Unfortunately, it's not you.
30:04It's this cancer.
30:08What is this?
30:09I've never heard the name Casey Zink in my entire life.
30:11Yeah, of course not.
30:12There's probably five layers between you and Casey.
30:14But he's the one that your shell company ran tests on.
30:18He's dying because of what you did.
30:24You're fired.
30:25You might not want to leave.
30:27I have some more news for you, brother.
30:30You, your company, or whoever, you sent Casey some follow-up surveys.
30:35He reported no side effects.
30:36You don't strike me as a patient, man.
30:40So when he said he was fine, I'm guessing that you gave yourself exactly what you gave him,
30:46and probably more than one dose.
30:49Am I right?
30:50Nothing you're saying is accurate.
30:52I acknowledge nothing.
30:53I admit nothing.
30:55Dr. Watson?
30:57Good morning, Casey.
30:58Good morning.
30:59This is Joseph Bell.
31:01He created a company called Primal Biotech.
31:04He's the one that made you sick.
31:06No.
31:06What?
31:07That's not true.
31:08It's not true.
31:08See, here's the thing.
31:09He's also sick himself.
31:11Joseph infused himself with the same thing he gave you, and we checked his markers.
31:15He doesn't know it yet, but he's very, very ill.
31:19Well, Joseph has cancer, too.
31:28No.
31:30No.
31:31I'm Joseph Bell.
31:33I have the liver of a 22-year-old.
31:34You've got cancer, Joseph.
31:36A very unique and difficult-to-treat form of cancer.
31:40No.
31:42No.
31:42It's in your spine.
31:45I understand this is a lot to take in, and I encourage you to get a second opinion, if
31:49you like.
31:49I have my blood red every single morning.
31:51Yeah, but they're not looking for these very specific tumor markers we did.
31:55We have a treatment.
31:56If you're interested, I'd say right now, my clinic is the only place in the world that
32:01can help you.
32:01You said the cells can't be killed.
32:03They can be convinced to kill themselves.
32:06We developed an SI-RNA treatment, and Casey's already getting it.
32:11If you want, we can do the same for you.
32:14I'm your doctor, just like I'm Casey's doctor.
32:16Of course I want it.
32:17If I'm really sick, of course I want it.
32:19Why would you even ask me that?
32:22What are you going to do for Casey's sake?
32:24I'm already paying for his treatment.
32:25What else do you want from me?
32:27He has your death rights.
32:28You created primal biotech.
32:30You gave him cancer.
32:31So you say.
32:32So I know.
32:34I'm the only person in the entire world that could be your doctor.
32:38There's a sick kid in this room who has cancer because of you.
32:42As far as I'm concerned, whatever he wants from you, you do it.
32:47Or else.
32:48I can only take so many patients.
32:50It takes time, you know, to find the right person.
33:07First they send me to therapists, psychiatrists.
33:11Then I found a few of my own.
33:13Most are very easy to manipulate.
33:15Now I have one who helps.
33:17And does help.
33:18I'm never doing talk therapy.
33:22Okay.
33:27Why, though?
33:28You're a scientist.
33:29There's data.
33:29Stephens Croft, the fourth, didn't do much with everything I've handed to him.
33:35You're fifth.
33:37Stephens, four, was a very good club tennis player and not much else.
33:40He smiled a lot.
33:45He was depressed as hell.
33:47After the divorce, he went to maybe four psychiatrists that I knew about.
33:55The last one got really close to him.
33:58Conversations day and night.
34:00It was weird, but he said it was helping.
34:03Then he crashed his car on Cape Cod.
34:06Died in a helicopter on the way to the hospital.
34:13And those things are connected.
34:17Maybe not.
34:17Maybe yes.
34:20It was an accident.
34:23Unless it wasn't.
34:25What do you think?
34:27I've never said this to Adam.
34:30Not to Sasha, not to anyone.
34:34I don't think that wreck was an accident.
34:38I think my dad did it on purpose.
34:42I'm never going to therapy.
34:44Stephens.
34:47I'm sorry about what happened to your dad.
34:50Okay, whatever it was, I'm sorry.
34:54You've never said this to anyone.
34:57Why say it to me?
35:01Because you understand.
35:02Thank you so much for coming.
35:12No problem.
35:14I have to be honest, though.
35:16I am a little nervous.
35:19You'll be fine.
35:21Just sit with her, watch her shows.
35:22You okay?
35:37I have a hair appointment.
35:39It's been a while.
35:41Of course.
35:42Do what you need to.
35:43We'll make it.
35:45You have my number if you need me.
35:47Who are you?
36:14Um, my name is Stephens Croft.
36:21I'm here in case you need anything.
36:27I'm here to spend time with you.
36:32That's good.
36:34I'm glad.
36:35Still doing rounds today, sir?
36:55Sure ain't necessary.
36:57And I don't do rounds.
37:00I shadow people doing them rounds.
37:02Okay, you're still shadowing people doing rounds?
37:05I am indeed.
37:06Tell you what.
37:08You hang a few feet back,
37:10you observe all you like.
37:12Thank you, sir.
37:16Thank you, Shinwell.
37:20That's a weird name.
37:21You're doing great, Casey.
37:32Your sales are really responding to the treatment.
37:34I got lawyers coming by later.
37:36It's like, you know,
37:37everyone wants to know me all of a sudden.
37:39No, it's because you're money in the bank.
37:40You're going to make it.
37:42And you're going to get everything you want.
37:44You should start thinking about what you're going to do with it.
37:46Who are you going to be now, Casey?
37:49These numbers.
37:50They're not good.
37:52I know.
37:54The cancer is mutating too fast for the treatment to take hold.
37:57My lawyers are giving that kid everything he asked for.
38:00We're playing ball.
38:01It's not like paying a fine.
38:03This isn't something you can control.
38:06I'm sorry.
38:07We're going to keep trying,
38:08but you really should be in the hospital.
38:10With all your power
38:13With all your power
38:17With all your power
38:22What would you do?
38:28With all your power
38:30With all your power
38:35With all your power
38:39What would you do?
39:05Hello, Mycroft, that's my desk.
39:19Did you pay for it?
39:21Get up or it won't be lawyers solving no problems.
39:25I can give you what you want, I can make myself scarce, I can leave you to run this clinic
39:31under your own auspices.
39:32Very good, thank you, goodbye.
39:33If you haven't heard me out, you need to give me something in return.
39:39My company is reeling, the formula that my brother left doesn't work the way that he
39:45said it would in the will.
39:47Sherlock did this, Dr. Watson, he left that poison pill behind to wreck everything I built
39:51in both our names.
39:52I don't know anything about that.
39:55I think you do, Sherlock's alive, he has to be.
40:01He's watching somewhere, he's laughing.
40:07Tell me I'm right.
40:09Tell me my brother's still alive.
40:11Tell me where he is.
40:12Tell me what I need to know and I will withdraw from your business directly.
40:18I'll leave you alone.
40:20Where is Sherlock Holmes?
40:23He's following up.
40:26Mysific Dave St富.
40:29He's playing somewhere.
40:30He's playing somewhere the cheapest证.
40:32Sandra Lewis has a Pulgot to Test apodcast!
40:34I will nicht be!
40:35Tell me what he's doing!
40:37isto is the most beautiful.
40:37Your mister is the most crunchy.
40:39Who's falling into that void?
40:41You're just aồling, you're not getting súbparty!
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