Brazilian Breakthrough Drug Shows Promise in Reversing Spinal Cord Injuries

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00:00Brazilian breakthrough drug shows promise in reversing spinal cord injuries.

00:05For decades, spinal cord injuries brought sudden loss of movement, sensation, and independence,

00:10with few therapies to repair the damaged wiring.

00:14A breakthrough drug from Brazil, Polylaminon, led by Tatiana Coelho de Sampaio at the Federal

00:19University of Rio de Janeiro, shows promise in helping damaged nerves regrow.

00:25Still experimental and unapproved, it could offer hope to millions.

00:32Think of laminin as the body's scaffolding, helping cells move and grow.

00:36Brazilian researchers created a stable form called polylaminin, which may help nerve fibers

00:41regenerate after spinal cord injuries.

00:44Scar tissue blocks healing, but polylaminin tackles this by rejuvenating neurons to sprout

00:49new axons and re-bridging brain-spinal links, using a biomaterial that helps the body repair

00:54itself.

00:59Animal studies show polylaminin boosts nerve growth and movement, with dogs regaining some

01:03ability to walk.

01:05In humans, trials are still early, with only a few patients treated near injury sites.

01:10Some patients regained slight movement, but results came from small, uncontrolled trials.

01:15With no approval yet from Brazil's Anvisa, polylaminin remains experimental, promising but

01:20not a guaranteed cure.

01:25In spinal cord injuries, messages from the brain can't reach the muscles.

01:29Polylaminin may help rebuild these connections, promote nerve growth, reduce damage in new injuries,

01:35and support rehab or other therapies.

01:37The next step is larger trials testing polylaminin in new and chronic injuries, determining dosage

01:41and delivery, and proving safety.

01:46High-spread use requires consistent results and strict quality control, but early findings

01:50are encouraging.

01:51In the a months following, the last step is required to reach the body of the system.

01:51In the water is required to reach the body to help the body of the body.

01:55The next step is added.

01:57What's the most important thing that you think is usually being submitted?

02:01The next step is for the rest of the energy.

02:03The next step is for the best is for the quality of the body.