00:00जम्मू कश्मीर के श्रीनगर में शेरे कश्मीर कुशिविज्ञान एवं प्राध्योगी की विश्विद्याले ने एक एहम उपलब्दी हासिल की है।
00:10यहां शोद करता भारत की पहली जीन संपादित भेड तमीम विक्सित करने में काम्याब रहे हैं।
00:16जीन संपादन एक व्यग्यानिक तक्नीक है जो किसी जीविद जीव की आनुवनशिकी में डिने अनुकरम डाल कर या उसमें परिवर्तन कर बदलाव लाता है।
00:28तमीम विक्सित करने वाले शोद करताओं की टीम ने कुछ भेडों के भुरूनों में एक खास जीन डाला।
00:35फिर उन्हें प्रयोक्षाला में विक्सित किया।
00:37इसके बाद उन्हें एक सरोगेट भेड में स्थापित किया।
00:40इस वैग्यानिक कोशिश से जुड़ूआं मादा मेमनों का जन्म हुआ, जन्में से एक में संपादिच जीन था।
00:48We select some sheep animals and they act as the donors.
00:54We do leproscope assisted flushing in them and collect embryos from them.
00:59Those embryos, they are either one day, two day old or whatever, they are of different stages.
01:04We collect them and get them into the lab.
01:07After the gene editing machinery is injected into these embryos, these embryos are kept in the incubator which is over here.
01:17And still about seven days till they reach the blastocyst stage.
01:22And we have been successful in producing the first gene edited sheep of India.
01:26And it's named Tarmeen.
01:28Shodh kartaoon ne kaha ki wye gene sampadan ka asar samajne ke liye bheđon ka visnit adhyayan kar rahe hai.
01:36There are many genes which can be targeted for gene editing.
01:39So this was just a proof of principle to show that we can produce a gene edited embryo.
01:45And then we can produce a birth from that embryo.
01:50So this was an initial experimental patient.
01:54If we look at it, it's almost six months, six months.
01:58So it's growing.
02:00So now we will analyze this body weight.
02:02So now we will analyze this body weight.
02:04How much is the gene editing?
02:05And what is the gene editing?
02:07And what is the gene editing?
02:09So that's yet to be tested.
02:13Shodh kartaoon ka dawa hai ki gene sampadan teqneek se swasth
02:17aur zyada utpadan karne wale pashudhan vixit karne me madad mil sakti hai.
02:22Since we have been able to demonstrate our capability of doing gene editing successfully,
02:28and we have been able to produce a live animal,
02:31I think this has revolutionized gene editing studies in India,
02:35especially in our lab, especially in Skost K.
02:38And by gene editing, we can produce, as I already said, disease resistant animals.
02:43We can produce double masked animals.
02:45And, you know, since we are using the cutting edge technology,
02:49the CRISPR gas technology,
02:51so our editing is very precise.
02:53And whatever the domain, whatever domain we will be working,
02:58it will have a precise gene editing with the least side effects, negative effects.
03:03Shere Kashmir vifshere diyalay mein tamim vixit karne wale shodh kartaoon ko umeed hai ki unki kooshishoon se
03:10pashudhan anonwanshik engineering me bharat ki shamtah ko vashwik maanwetha mil egi,
03:16jis se jayev chikitsa or kruishi anusandhaan me kranti aayegi.
03:24It's out of the corner.
03:26Do you have a plan?
03:27I've decided to work with my Over-Stock Kuntala,
03:28but this is the middle end of the screen.
03:30It is the middle end of the screen.
03:32It's not easy.
03:33It's not easy.
03:34Yeah.
03:35It's not easy.
03:36I'm gonna do it.
03:38It's not easy.
03:39But you've decided to do it by playing real.
03:41It's not easy.
03:42It's not easy.
03:43It's not easy.
03:45It's not easy.
03:46It's not easy.
03:48It's too easy to figure out.
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