This system was discovered in 1900 by the German doctor Karl Landsteiner, who, by mixing the blood of different people, discovered that only certain types of blood could be mixed with a certain transfusion. For this discovery he received the Nobel Prize in 1930. He discovered two antigens that are on the surface of red blood cells, and called them A and B. Due to the fact that the blood of some contains: a certain antigen or another, both antigens or neither, he divided blood types into 4 different groups: A( II), B(III), AB(IV) and 0(I). On the other hand, he noticed that blood contains antibodies that differ from one blood type to another.
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