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Researchers at the University of Virginia Comprehensive Cancer Center used focused ultrasound and microbubbles to briefly open the blood-brain barrier and deliver nanoparticles carrying microRNAs against glioblastoma, ScienceDaily reports. The focused sound briefly opens the barrier, allowing the particles to reach the brain. In laboratory and animal models, the treatment slowed tumor growth and helped animals survive longer. Glioblastoma, the most common malignant brain tumor in adults, claims more than 13,000 lives in the US each year. The team hopes to move toward clinical trials, but the approach is experimental and has not yet been tested in people.

Disclosure: This video contains stock footage and content created or enhanced using AI-assisted tools.

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00:00Researchers are using sound waves to sneak cancer-fighting molecules into the brain.
00:04The target is glioblastoma, the most common malignant brain tumor in adults.
00:09It claims more than 13,000 lives in the U.S. each year.
00:12One big obstacle is the blood-brain barrier, which blocks many drugs.
00:17That makes these tumors especially hard to treat.
00:20A team at the University of Virginia found a way around it.
00:23They use focused ultrasound, guided by MRI, along with tiny micro-bubbles.
00:28Together, they briefly open the barrier.
00:31That lets nanoparticles carrying micro-RNAs slip into the brain.
00:34Micro-RNAs are tiny genetic molecules that can switch off several cancer-driving genes at once.
00:40In lab and animal tests, the treatment slowed tumor growth.
00:44The treated animals also lived longer.
00:46It's still experimental and hasn't been tested in people.
00:49The team hopes to move toward clinical trials.
00:52Disclosure.
00:53This video contains stock footage and content created or enhanced using AI-assisted tools.
00:58We're looking at including a previews that have been tested in each piece of today.
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