Microorganisms That Target and Eliminate Cancer Cells

Researchers are investigating an unexpected new method to combat cancer — by utilizing bacteria. :microbe:

In a recent investigation, scientists altered a probiotic strain known as E. coli Nissle 1917 to synthesize Romidepsin, a potent anticancer medication. These modified microorganisms specifically accumulate within tumor sites and release the drug precisely where it is needed.

In trials involving mice with breast tumors, the bacteria effectively inhabited the tumors and inhibited their growth by administering the drug locally. This precise targeting could minimize harm to healthy cells and enhance the accuracy of cancer therapies.

Nevertheless, this technique has only been evaluated in mice at this point. Researchers still need to validate its long-term safety and develop dependable methods for managing or eliminating the bacteria post-treatment.

If forthcoming research proves successful, these tiny modified microbes could emerge as significant new assets in the battle against cancer.