- 1 day ago
THR senior vp sales and brand strategy Liz Culley sat down with Dr. Blair Murphy Rose, Jennifer Hollander MSN, FNP-C and Dr. Drew Taylor for the Hair Today, Hair Tomorrow: A Little Science. A Lot More Hair" panel, which touched upon scalp health and hair loss.
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00:06we are closing out the day with hair because it is a big topic we mentioned a little bit of
00:12ozempic here and there i can't wait to tap that back i'm like counting the days until i'm done
00:17breastfeeding and i'm just gonna hook myself up um and then really let all my hair fall out
00:23just i'm just kidding um so we're gonna talk about hair because it's a new topic that
00:29everybody wants to talk about and then you can go get your gifties and um i've actually also put my
00:36cell phone number on a big screen as you go to get your car um we have jennifer hollander here
00:43today
00:43who i found out yes is also a san francisco girl okay same 415 do you have a 415 inner
00:52sunset oh
00:53richmond girl okay we'll talk about high school later sure there's a little overlap uh co-founder
00:59of the hollander clinic and board certified family nurse practitioner which we love um what i i mean
01:06all everybody's bios are so esteemed and what i loved also about yours is you've become such a
01:11trusted leader with rosacea surgical and acne scars melasma hyperpigmentation you also have been very
01:18much recognized for your advanced skill in caring for ethnic and diverse skin types delivering natural
01:23refined results that respect every patient's individuality i love that but that's really
01:28important and incredible um you're welcome and i'm going to do things differently i'm going to
01:32actually give everyone's bio and then i'm going to ask questions how is that good i got to spice it
01:36up people are starting to fall out i also had a double espresso and i feel crazy
01:44it's the truth i'm like sweating and i feel like i'm going to fly right on out of here
01:48um we have dr blair murphy rose who is a bird's board certified dermatologist down south in the oc
01:57and in new york city uh you are an accomplished cosmetic medical and surgical dermatologist
02:02specializing in leading facial rejuvenation techniques um my wife is very excited to go see
02:09you for some rosacea issues um but love that you are here today so thank you for being here thanks
02:15for
02:15having and then we've got dr drew taylor and let me tell you i am scared to read the bio
02:21because it
02:22is so impressive and so not look at you we talked earlier i told you i was like is this
02:27a sci-fi novel
02:28what am i reading you are a genius what is happening um a pioneer entrepreneur and ex baseball player
02:37i i lied i wasn't going to say it and then i did um and you are really bleeding the
02:42charge in
02:42regenerative medicine with acorn which we're going to get into which focuses on hair and skin
02:48regenerative serums i feel like you sleep standing up i we're going to get into it um you have such
02:56an
02:56illustrious illustrious career you've been the chief science opera officer at epic capital management
03:03um mount sinai bioengineering of skeletal tissues team i mean this this is exciting i'm very excited for
03:12this so we're going to start uh with you jennifer um we're seeing a lot of scalp health talk out
03:22there
03:23um i myself have been to a few japanese scalp treatment salons honestly i just think i got a
03:29good blowout i don't really know what they showed my follicles on a screen and they looked absolutely
03:34terrible and i was like okay bye um and i know a lot of people are coming to you for
03:39new treatments i
03:40didn't even know that you could do treatments for scalp health um but for those that are kind of
03:47getting the influx of over the counter or like what we can do at home what do you suggest and
03:55why do we
03:56need good scalp health or do we need it yeah absolutely i mean it's it's really interesting we spend so
04:03much
04:03money and so much resources on lasers and skincare thousands of dollars for our face and for our
04:11bodies yet we completely um leave out the scalp and the scalp is just an extension of skin from our
04:18face
04:18so it still has a barrier it still has the ability to experience chronic inflammation um whenever we're
04:25doing procedures like microneedling or prp or nanofat with prp when we're injecting into the scalp for
04:31regeneration we're trying to increase blood flow circulation neovascularization things to help
04:37kick off that hair growth cycle if you're working with a unhealthy scalp where you're experiencing
04:46a lack of blood flow a lack of circulation build up in the scalp and you're not caring for your
04:52hair
04:52properly you're spending money and resources on all of these technologies but you're kind of getting
04:57maybe like 50 of the result that you would get if you had a healthy scalp hair is very emotional
05:03when patients come in they're sort of distraught they've tried everything under the sun and our
05:08approach to scalp health or hair restoration in general is very holistic so in the same way that
05:14i approach skin health i also approach scalp health we talk about what the underlying current is what
05:20the patient's been experiencing we look at their blood work we look at their you know iron panel
05:25uh thyroid panel vitamin d levels chronic stress those things are all direct contributing factors
05:32to hair hair loss or telogen effluvium um and women i feel like experience hair loss a little bit
05:38differently than men do most of my patient population for hair restoration are female um you know if we if
05:44i have patients who have like profound hair loss i don't waste any time talking about you know this shampoo
05:49or this topical treatment i'll refer out and that's one of the best things that you can do either to
05:54a
05:54dermatologic hair specialist or to a surgeon who specializes in um transplantation um with what we
06:01do we we talk about sort of that baseline what's happening internally uh we help to regulate that
06:08either with their primary care provider or they can work with me directly and then we get them on a
06:13regimen for scalp health and there's a line that i use there's so many different lines on the market
06:17um sometimes dermatologists will recommend things like um you know different steroids to address
06:23maybe seborrhea or if um you know they wanted to actually start using some topicals for hair growth
06:29like minoxidil now we have oral minoxidil on the market most of my patients don't want to take any oral
06:34medications they want to see what they can do sort of as a primary prevention first and start using products
06:40and maybe some other types of interventions like microneedling and prp but we we have them go on a
06:47scalp health regimen that helps to hydrate the scalp gently condition the scalp but then also restore
06:55you know hydration because with inflammation comes trans epidermal water loss which can increase that
07:01inflammatory cycle and so kind of getting homeostasis back into the scalp i think is just sort of
07:06foundational before doing any type of intervention whether it be microneedling prp prf or the secret
07:12homes i mean the water in la is garbage right no never nobody's taking a shower around here i mean
07:19it's like the hardest water i can't even believe it do you think everyone in la should go and like
07:26put those osmosis machine this again this is my question to you because i'm really trying to
07:30convince my wife that we need one of these should we change all of our i mean is it also
07:34the water i can't
07:35help it's a contributing factor for sure um but i think that just like if you can't invest in
07:40something like that you can just get one of those shower filters that you change maybe once in three
07:45months i honestly don't know if those work yeah i mean i think they kind of it's a lot of
07:50hope in a
07:50in a showerhead but i i i think that i i i think that maybe using some type of scalp
07:56oiling treatment or
07:58something that's like a clarifying shampoo once a month something that's helping to chemically resurface
08:02the scalp in the same way that we take care of our skin it's not any different yeah so fora
08:07was
08:07saying that hair care was and the approach to it um from a skin care perspective was one of the
08:13biggest growth markets that they've seen and so i think we're all getting and now i've talked about
08:18it so it's a wrap my instagram is going to be nothing but you know hair products but i think
08:24it's just
08:26something that people want to know like does it actually can we do some things at home before we come
08:31in
08:31office which we'll get into in a moment but you know can't do they actually work and is scalp health
08:37really actually important it sounds like it is yeah i mean it would basically be saying is skin health
08:42important it's the same thing and not not here of course we wouldn't be saying that and i would say
08:47that um you know with hair it's so um you kind of want to throw everything at it when you
08:53look at the
08:53literature a lot of times um things that are done singularly like just minoxidil on its own doesn't work
08:59quite as well as maybe minoxidil with microneedling got it with tretinoin or something that's going to
09:03help to potentiate the penetration of the active got it well that's a perfect segue for dr rose who
09:09i know you do a lot of these treatments down in the oc and in new york for somebody who
09:14is you know at
09:16kind of they've tried everything at home but they really want to seek out treatment what is kind of
09:22the first line of in office treatments that you would recommend yeah well i love that you say that and
09:29you know we would be i'm so grateful that hair is a topic here it's hard to go on a
09:33hair panel and
09:34not talk about the fact that it's very important if you are alert if you are noticing some hair
09:38thinning go see your specialist right away because it's we can do a lot of things there are a lot
09:43of
09:43treatments we have some exciting new technology and um there are many different causes of hair
09:49thinning and not a lot of my patients realize that in fact a lot of the times when i treat
09:52someone
09:52for hair loss it's because they're coming in for their skin check which is great or they're coming in
09:56for you know something else and either they happen to comment on it or i notice it when we talk
10:02about
10:02the hair thinning it's becoming more and more common it's incredibly common so i sometimes my patients
10:07are embarrassed to bring it up and i don't and i hate that because it's so much more common than
10:12you
10:12realize it's uh hormonal hair thinning in men is very common it's also very common in women we have
10:17some really great treatments for that both medical that is topical oral and then some devices that that are
10:24emerging some that are older and some are emerging so just you know i encourage everybody here i'm
10:30i'm sure some people here and i'm not looking but like are i've noticed that their hair and we we
10:35know
10:35our hair much better so i can sometimes i look a patient and they have the most gorgeous full head
10:39of hair but they're like i'm losing so much hair i used to have this beautiful head of hair you
10:43know
10:43your hair better and so you know the exam is one thing and we can talk about what that mean
10:48entails but
10:49just how somebody has you know they're noticing that they are losing more hair their hair their
10:53ponytail used to be twice as thick as it is now that's more important to me than what i see
10:58clinically
10:59in terms of do i think you have you know have you lost your hair but when we examine the
11:03scalp we talk
11:04about is scalp health important it's incredibly important we've learned more and more about how
11:07scalp health is very important because inflammation in the scalp which we see a lot with dandruff or seborrhea
11:13and other things can inhibit hair it increases hair shedding and inhibits hair growth so very
11:19important that you're we're addressing scalp health as well but in my office when someone comes in we
11:24talk about hair thinning we talk about everything from head to toe and i want to diagnose first
11:28what type of hair thinning do you have there are several different ones and we address those differently
11:32we talk about oftentimes if someone has a positive hair pull which means you know they're actively
11:37shedding then we'll go and the next step is oftentimes to get their blood work checked and she talked
11:41about some of the things we look at vitamin d deficiency is a very common cause of it iron
11:45deficiency thyroid disorders there are things that we can very quickly check in a blood simple blood
11:50test and then address those if it's just as simple as gosh you need to get some more vitamin d
11:54supplementation and i've seen that across the board make a big difference in a lot of patients so all
11:59that to say if you find that you are suffering with some hair thinning go see your dermatologist go see
12:04a
12:04specialist so that we can help you along um we have we've just incorporated a new technology so then
12:09to talk about some of the technology we have just incorporated the alma tet i was so excited to see
12:14that they are here because this is a great um you know we've been doing micro needling with prp for
12:18a
12:18while or just prp injections alone this can be quite painful and so many of my patients you're supposed
12:23to do a series of treatments to get the best results some people can't tolerate that or don't
12:27want to tolerate it or don't like the mess of it so the alma tet is a new needle free
12:32blood free way to
12:33um deliver you know proprietary serum that has shown really great promise in increasing hair
12:39thinning just with ultrasound and air pressure so just some of these things you know you may not
12:44even know about them but get in see your doctor and talk about what's going on so you can figure
12:48out
12:48why you're losing hair what's going on we see so much of it with the new peptides that everybody
12:52you know is taking and there are things we can do that's that's amazing i'm like i'm what kind of
13:00shed
13:00am i shut what did you say again type what was the kind of shedding hair pull test so you're
13:07not
13:07actually just pulling your hair it's just if it falls out right that's it no i'm like that's it you
13:13know classically 25 hairs gently pull and if one comes out that's a positive hair test we do it
13:18oh interesting okay well speaking of hair pulling uh dr taylor who has a lovely set of hair i will
13:28say
13:28i mean it really it's very handsome um as i said when i was researching acorn and the incredible
13:36product you've created you i was mind blown alicia and i were you know we were prepping for this and
13:42i
13:43just was so floored at what has been happening in science and so i want to talk about how you
13:51even
13:51came up please explain it because i'm not going to explain it correctly obviously this espresso is taking
13:57me on journeys here but i just i mean it's so incredible that you're essentially using our own
14:04skin cells and hair follicles to create more hair growth and obviously skin but today we'll talk about
14:10the hair growth so can you explain what you've created and how it works sure i'm gonna take one
14:15step back from here and just kind of big picture and what we're trying to accomplish and then we'll zero
14:20in on on hair perfect um but ultimately the this and all of the talks today have been really about
14:26this amazing revolution that's happening in regenerative aesthetics so regenerative medicine
14:30to me um as as that's what i ended up studying regenerative medicine stem cell biology is really the
14:37opportunity to bring our performance to a previous state using our own biology so that that loss that can
14:44happen can be due to age it can be due to damage disease any of those things can we actually
14:50bring
14:50ourselves back to a previous state of function and use our own biology to be able to do that so
14:55that's
14:56the promise of regenerative medicine and it gets trapped in in different corners of of amazing
15:00institutions like not many people know there's uh eight people walking around the u.s right now with a
15:053d printed printed bladder from their own cells and and that's been incorporated into their bodies and
15:10given them the ability to to obviously function and things so the amazing benefits from regenerative
15:14medicine but it all starts with cells wow that's crazy like how well but see i could lock all of
15:23you
15:23in here and i have so many questions but wow that's fascinating yes we'll stick with hair though so yes
15:28the the big um you know question is if if all of the this next revolution in regenerative medicine
15:34is going to be accomplished with access to cells then cells are the next currency in our health care
15:39and what we need to be doing is making sure that we have access to the best version of that
15:43for ourselves so that we can leverage that now today in regenerative aesthetics and beyond into
15:48all of these other areas of medicine and so what we've done is really evaluate ways to capture quality
15:54cells from patients in a physician's office very easily because we have to remove the barriers to be
16:00able to access these things you can't have a patient that has to go to the specialized facility or
16:05hospital the cryogenics lab and all of these different areas or the previous ways that we were doing
16:10this drilling into their iliac crest for bone marrow or or capturing cells in very invasive ways so what
16:16we've really done is try to target opportunities to collect cells non-invasively and plucking follicles
16:22is the the best access that we have to mesenchymal stem cells these quality stem cells that are leading
16:28the charge in regenerative medicine right now that we can then capture without having to do anything
16:32invasive or have something that's that's painful for that patient to go over my beautiful wife and i have
16:37three young boys at home the youngest nine they've actually had their cells collected and cryogenically
16:42preserved of course i would never subject them to a bone marrow tap or something and so now they have
16:47their own biology locked in place and obviously we're leveraging that today in this amazing bright
16:53future in regenerative aesthetics with treatments across hair and skin and even scar revision
16:59how did you even think about coming up with like i mean obviously you've spent years in science
17:05but did it feel like i mean you say barrier to entry and i also think people can are focused
17:11on their
17:12looks right so hair skin a good place to start but do you see that perhaps there is a future
17:20where
17:20folks can you know use the technology that you've created for i don't i mean did you say a new
17:26spleen a new
17:27what did you say i i blacked out i was like what 3d printed in my body it freaked me
17:33out i'm not gonna
17:34lie it freaked me out those are examples but you know we did publish a paper last year that where
17:38we were able to take the hair follicles that we're using in treatments live today and i'm really grateful
17:43to have some amazing partners that are in this room some of the leaders in in aesthetics but you know
17:48those those cells we've been able to actually use to create other cell types so yes we've been focused
17:53on hair and skin but we've also turned them into cartilage bone fat neurons pancreas cells even nk cells
17:59that target cancer and senescence so it is it is really a a bright opportunity and and i think
18:05that why it's it's exciting to be on the hair panel is because it really highlights the power
18:09of our hair follicles they really are these miniature organs that we have you know very superficially on
18:15our on our on our scalp that that contain some extremely powerful cells well and it was mentioned
18:21before on a previous panel and a little bit here but you know hair is very emotional for people you
18:27know and for a variety of reasons and so i think having more knowledge about you know how to regrow
18:34but it's out there people i think get really frustrated when the at home things aren't working
18:39or those shampoos or those serums or the gummies like how many hair gummies am i gonna eat i'm like
18:45what like what am i eating right now just like crazy horrible flavored teddy bear gum thing that does
18:51nothing but you know what i mean but i think if people had an understanding that they had hope
18:56that could be done with lasers you know i think it's scary for people some people don't want to go
19:01to turkey you know yes me included like amazing options in this room um so we don't need to go
19:09to
19:09turkey but yeah i mean you called it earlier right the the hair space is one of the fastest growing
19:15spaces right now in aesthetic medicine um and for good reason i do think that there is now a wave
19:21of
19:21attention in hair that hasn't existed previously and and we have a a heightened focus around the
19:27actual therapeutics and some of the opportunities that we have and there's there's a slew of new ones
19:30that are i still think many years away that are still in those those early phases of testing
19:35but we're also really seeing hair as a great target in regenerative medicine and as regenerative
19:40medicine is surging and regenerative aesthetics is resurging we're seeing a lot of that
19:45um used in in hair specifically um and that's really because you have a now a greater knowledge
19:51of the hair follicle itself most of the time we were targeting therapeutics were actually um targeting
19:56the the cup at the bottom these dermal papilla cells and what we've learned is the cells that
20:01actually we lose faster the mesenchymal cells that are present in the inner outer root sheath as well
20:05as the bulge area so you can see these you know if you do histology on on follicles that aren't
20:10performing and producing hair anymore you'll see the presence of the dermal papilla but it's very
20:14difficult to stain for these mscs and they're responsible for releasing factors and these are
20:19big words that we we know you know these are exosomes extracellular vesicles these are matrix
20:24molecules like collagen elastin fibronectin agracan one specific to the hair follicle or more specific to
20:30the hair follicle cytokines to to lower the the immune inflammation pathways and and polynucleotides
20:37all these things are released by these mscs and they deliver that value to the dermal papilla
20:42what we've done in our first wave of delivering this this intervention is is captured that in
20:47the laboratory that same process so by plucking your follicles and freezing them you lock them
20:51in time but we can actually draw them out and we can put them in a system where they are
20:56primed to
20:57release high concentrations of all of these factors exactly what they're supposed to do in the human body
21:02we capture those over time because we do that over time we can offset the effects of that
21:07patient's age potentially their health and a number of other factors that might lead them to not have
21:13cells that produce as much of these fault these factors in real time in their in while they're in
21:18their head in the lab we can actually optimize that and make sure that we reach these these critical
21:22thresholds and then deliver those back and obviously we've got amazing partners that are doing that
21:26today and they're re-infusing these essential molecules back to stimulate our dermal papilla in the
21:31hair follicle cells to continue to produce keratin and and for those that that are already producing
21:36care to produce more of it so really the targets are thickening hair resetting dormant follicles
21:41you know taking vellus hair follicles into full hair follicles and we've seen some pretty dramatic
21:46results we're really excited about well listen we got to redo the pr on plucking hair follicles
21:51because i just think of really intense drug tests from like law and order okay well there you go
21:57nobody in this room okay it sounds like we did not have the same high school experience in san
22:01francisco but you know i was like so scared like don't pluck my hair um but i again i i
22:08not to even
22:09repeat myself but i do think hair is so emotional and i love that all of you are really thinking
22:14about from the inside out whether it is you know looking at the overall health looking at skin look
22:20looking at what you can do in office out of office and thinking of it in a 360 way i
22:26think is really
22:26important yeah i think just piggybacking on what you're saying um that sort of third prong is having
22:34that really honest conversation with the patient sure and giving some anticipatory guidance as to
22:39like on the whole on an average of what we see and uh what the outliers are and kind of
22:45creating some
22:45realistic expectations because it really does vary after working in you know both in dermatology and plastic
22:50surgery for long enough i really haven't seen like one silver bullet that's like really nailed
22:55hair um it's really been a variety of things it's been very case by case and so i think if
23:01you lay
23:01that out there with the patient you're already going to set them up for a better outcome because
23:05they have a you know they sort of have a better mindset about okay what's realistic for me and you've
23:09sort of i tend to underplay things so that if things actually do you know uh come out well they're
23:15they're pleasantly surprised and you know they have a realistic mindset about it well and i think
23:19that's really fair and that's why i was asking sort of the questions like what can you do to prepare
23:24for in office treatments because hair is real it does seem to vary vary and there also seems to be
23:31so many products on the market promising hair growth and that's a very it sounds like it's a very difficult
23:38thing to do really actually and some of the best treatments truly are in office prescriptions and
23:44devices so that's why i say you know so many of you have a really great platform make sure you're
23:48educating people who are your followers and who's listening because it does affect hair loss affects
23:53your confidence so much and you will connect with so many people that want to know that there are
23:57options um speaking of options i have to say with all due respect to the brilliant mccreen botox and
24:03dysport are amazing we can't do without them i'm ticking the days down i'm telling you well i'm thank you
24:11so
24:12much for being here thank you for also being in the heat here we're proud of here
24:16you
24:17you
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