00:00What is acute liver failure? Acute liver failure is sudden severe stoppage of liver function.
00:12Adhawadha liver completely shut down abdi na soal vahanga. So liver abdi na enna? Liver is a major
00:17abdominal organ. It is the most important chemical factory of our body. In fact, it performs more
00:23than hundreds of functions in our body to keep our body functioning well. So liver mukhyama,
00:29it produces many proteins which will clot blood. It also produces bile which is required for digestion
00:36of food. In addition, it provides continuous energy to our body providing glucose, fat metabolism and
00:42other. So sudden na yippa liver stop achna what will happen? So blood la toxins metabolize agama.
00:48They continue to stay in the blood. So they have negative effects on the brain cells. So adhanal
00:53brain cells vika madayana. So which we call it as brain edema or cerebral edema which it's
00:59itself is a major detrimental factor and it can lead to mortality. And again, it can cause
01:06sudden severe bleeding. A patient with acute liver failure, what is the usual presentation?
01:11Abdi na paathingi na? Patients can have severe nausea, vomiting, abdominal pain, jaundice reclame
01:16patients ka. Patients might feel very tired and fatigued. They are jaundiced usually with high
01:21bilirubin. Liver failure doesn't end up being a liver failure in acute liver failure. It usually
01:26becomes a multi-organ failure where the kidneys also take a hit. Kidney can fail. Patient might
01:32need a dialysis. How do we manage a patient who has landed up in acute liver failure? Usually
01:37management is divided as medical management known as surgical management. Medical management
01:41is you take the patient in ICU where you give them good supportive measures like put them on
01:47ventilator, support the kidneys by doing dialysis, by bloodless soothika rikritika, we do plasma
01:52ferrisis and all those things. And one more technique which we follow is to do a liver transplant.
01:58Liver transplant is the ultimate therapy. A patient who doesn't respond to medical management
02:02liver transplant is usually subjected to undergo liver transplant.
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