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00:00New study finds common medications could lower dementia risk.
00:05Dementia impacts 55 million globally, costing $1 trillion.
00:10A Cambridge study links common medications to reduced risk, using 130 million health records.
00:18The study analyzed 14 studies, finding antibiotics, antivirals, vaccines, and anti-inflammatory drugs reduce dementia risk.
00:32Hepatitis A, typhoid, and diphtheria vaccines, notably lower dementia risk.
00:41NSAIDs, like ibuprofen, reduce dementia risk by 12%.
00:46They block inflammatory molecules, protecting brain tissue and maintaining healthy cell communication.
00:54Infections significantly impact dementia, with hospitalized patients showing 70% higher risk.
01:01Blood, circulatory, urinary, and hospital-acquired infections increase this risk.
01:07Vaccines primarily prevent diseases, but may lower dementia risk.
01:12Cambridge study links hepatitis A, typhoid, diphtheria vaccines to reduce dementia, BCG vaccine to decreased Alzheimer's.
01:25Blood pressure medications, like ACE inhibitors, may reduce dementia risk by enhancing blood flow.
01:32As diabetes drugs' effects vary, more research on semaglutide is needed.
01:36Genetic studies show genes increasing dementia risk are active in brain immune cells.
01:46Chronic inflammation from diabetes, obesity, and heart disease can exacerbate neurodegeneration.
01:56Repurposing existing drugs can accelerate the development of affordable dementia treatments.
02:01Understanding the connections between infection, inflammation, and brain health is essential,
02:08and continued research remains vital.
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