What is Leucovorin? FDA Approves it For Rare Condition Tied to Autism Symptoms

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00:00What is Leucovorin FDA approves it for rare condition tied to autism symptoms.

00:06In a move that has given some people hope, while on the other hand drawing sharp criticism

00:10from leading medical experts, the Donald Trump administration recently took action to promote

00:15the use of an existing generic drug, Leucovorin, as a treatment for autism.

00:23Also known as folinic acid, Leucovorin is a form of folate, vitamin B9.

00:28The drug's connection to autism stems from research into cerebral folate deficiency,

00:33a rare condition where the body develops autoantibodies that block the transport of essential folate into the brain.

00:43While the FDA's technical action was limited to the rare CFD indication, the administration's

00:49rhetoric was significantly broader.

00:51In a press conference in September 2025, President Donald Trump and Health and Human Services

00:58Secretary Robert F. Kennedy Jr. presented the drug as a breakthrough treatment for symptoms

01:03related to the autism epidemic.

01:09The response from the majority of the scientific community and leading autism research institutions

01:14was immediate and overwhelmingly skeptical.

01:17They have stated that the evidence for using Leucovorin to treat the general population of

01:21people with autism is very, weak, and incredibly premature.

01:28Insufficient data.

01:30Researchers criticized the studies supporting the drug's use for general autism symptoms as too small,

01:35often limited to case reports or small randomized trials that lack the rigor necessary for widespread clinical use.

01:42Focus on genetics.

01:44Experts stress that autism is a complex neurodevelopmental condition largely rooted in genetics and is

01:49not caused by a simple vitamin deficiency.

01:56Autistic advocates emphasize that ASD is a natural human difference, not a disease requiring

02:01a cure.

02:05Leucovorin may help only a small subset of the autistic population who have a rare folate condition.

02:14The majority of the autistic population, who do not have this underlying metabolic deficit,

02:19there is currently no scientific evidence to suggest that Leucovorin will provide any benefit.

02:26That's it.

02:28I'm glad.

02:31And look out.

02:32The first thing you'll see is that Leucovorin can help you find.

02:34I guess Neucovorin's not only one, but the most important would be the most important

02:40in the situation.

02:42If you can actually get rid of the autistic population they should be more English.

02:44If you can hear it, please do not take.

02:45Not for sure.

02:47And if you want to understand what is the most important here in the society,

02:49the most important thing is.