00:00Basiedov-Greyev's disease causes symptoms, treatment and prevention, interesting about
00:06science and medicine, prepared by the editors of the channel AllScientifical.
00:10Basiedov's disease or Greyev's disease, the first toxic goiter, Flayani's disease,
00:22Perry's disease, is a disease characterized by increased activity of the thyroid gland
00:27and increasing the size of this gland due to autoimmune processes in the body.
00:37With goiter, an increase in the thyroid gland is observed due to rapid proliferation of
00:43cells in this gland, as a rule, this disease is associated with a lack of iodine in the
00:48body.
01:00Hyperthyroidism is one of the most common thyroid diseases, a few cases of this disease
01:07are less common than hyperthyroidism, it is still the second place after it among thyroid
01:14diseases.
01:20Basiedov's disease in many cases is inherited through the female line, most often the disease
01:27is transmitted through a generation from grandmother to granddaughter.
01:37As mentioned above, Greyev's disease is an autoimmune disease, it is the result of
01:44defects in the immune system, which begin to produce substances that interfere with
01:49the normal function of the body.
01:51The first goiter is characterized by the fact that lymphocytes begin to produce an abnormal
01:57form of protein that has a stimulating effect on the thyroid gland, this protein is called
02:03long-acting thyroid stimulator.
02:11Diffuse goiter, toxic goiter, is a very common disease, one patient per 100 people, most
02:17often young and middle-aged women suffer from it.
02:31The causes of Greyev's disease can be different, long-term chronic infection in the body, hereditary
02:39predisposition, viral infection, radioactive iodine, chronic tonsillitis, diabetes, idison
02:47disease with illegal hypoparathyroidism.
02:54General signs of diffuse toxic goiter, symptoms of Greyev's disease are almost the same
02:59as with hypothyroidism, which in many cases is the initial form of a disease.
03:05The disorder is characterized by symptoms such as vomiting, nausea, enlargement of the
03:10thyroid gland.
03:22Yearly symptoms of Basildov's disease, in the early stage of the disease visible symptoms
03:27are almost not noticeable.
03:29Greyev's disease, Basildov's disease, in many cases has individual symptoms, which
03:34makes it difficult to determine the correct diagnosis.
03:39Among the first symptoms you can notice sleep disturbance, trembling fingers, hair palpitation,
03:44crazy sweating, mood swings.
03:47More common symptoms include poor head tolerance, weight loss, even with normal nutrition.
04:05Change at eye level in Greyev's disease.
04:07A specific symptom of Greyev's disease is considered to be modification in the eye area,
04:13pronounced shine of the eyes, rare blinking, dark limbal symptoms, wide open eyes.
04:19Other things may also appear, such as eye damage, enlargement and bulging of the eye,
04:25aches of the thalamus, sensation of the sun in the eyes, double vision, which looking
04:31down with open eyes, a white stripe appears above the pupil.
04:36In healthy patients this does not happen because the eyelids, as usual, follow the eyeball.
04:43In patients, an increase in bulging of the eyeball is observed, sometimes the eyelids
04:48are characterized by swelling.
04:50Impaired nutrition of the eyes can cause various eye infections, inflammation of the mucous
04:56membrane of the eye, conjunctivitis, where nutrition of the eyeball is disturbed, optic
05:02neuritis appears.
05:03As a result, the patient may become blind.
05:07Skin modification, Basildov's disease.
05:09As the disease evolves, the patient's tremors become more noticeable through the body, the
05:15skin becomes moist, the patients are fuzzy, the skin through the body takes a dark shade
05:21and is more pronounced in the eyelid area, in some cases the skin in the area of the
05:26shines and feet thickens, the form of a dense edema, the volume of the thyroid gland increases
05:32and becomes more noticeable, when palpated, it has a dense character and no pain is felt.
05:40Cardiovascular disorders in goiters.
05:44Some of the most severe manifestations of diffuse toxic goiters are considered to be
05:49cardiovascular disorders.
05:51The patient begins to experience problems such as heart rate disturbances, rapid heartbeat,
05:57even during sleep.
05:59Many elderly patients often experience attacks of angina, an increase in blood pressure is
06:05noted.
06:06This disease can cause fatal heart failure.
06:12Increased motility of the gastrointestinal tract.
06:16Increased thyroid activity increases the motility of the gastrointestinal tract.
06:21The following symptoms appear.
06:23Nausea, diarrhea, and vomiting less often.
06:31Liver problems with goiter.
06:33With an excess of thyroid hormones, the liver can suffer because they have a toxic effect
06:38on this organ.
06:40In some cases, fatty liver degeneration develops.
06:49Disruption of the nervous system in basidov's disease.
06:52A high concentration of thyroid hormones in the blood can affect the functions of the
06:58central nervous system.
07:00Such conditions as insomnia, dizziness, headache, anxiety.
07:09Impotence and infertility in Graves' disease.
07:11With hyperactivity of thyroid glands, there are also disorders of the functions of other
07:17endocrine organs, and even genitals.
07:20A man's potency decreases.
07:22For a woman, the situation can become more complicated because menstrual irregularities
07:28and even infertility are observed.
07:32Distortion of sugar metabolism basidov's disease.
07:35There is an increase in the production of hormones by the adrenal cortex and glucose
07:41metabolites disorders, because of the latter, the patient is at risk of developing diabetes.
07:52Stage of Graves' disease.
07:54There are three stages of Graves' disease, mild, moderate, severe.
07:57First stage.
07:58During the first stage, the patient feels well.
08:00The purity of the heart contraction does not exceed 100 beats per minute.
08:05The patient notices a 10% weight loss.
08:08Moderate stage.
08:09During the moderate stage of the disorder, the pulse rises about 100 beats per minute.
08:14Blood pressure also increases and weight decreases by 20%.
08:20Severe stage.
08:21The severe stage is characterized by a weight loss of more than 20% and pulse rises above
08:27120 beats per minute, and side effects of the disease on other organs are observed.
08:45Diagnosis of basidov's disease.
08:47Diagnosis of Graves' disease is based on clinical picture, ultrasound examination,
08:52palpation of the thyroid gland, analysis of the concentration of thyroid hormones in the
08:57blood.
09:02Treatment of Graves' disease.
09:04Drug treatment.
09:05Treatment of Graves' disease is carried out by drug method.
09:07The main prescribed drugs that suppress the activity of the thyroid gland are thyrostatics
09:13propichil carbamazole, thiamazole.
09:16At the beginning of the disease, high doses of drugs are used, which are reduced over
09:21time.
09:22Treatment of the disease is carried out by monitoring the level of thyroid hormones in
09:26the blood until all signs of the Graves' disease disappear, at least a year.
09:31Also used are beta blockers, glucocorticoids, immunocorrectors, levothyroxine.
09:44Surgical intervention for diffuse toxic gutter.
09:47If drug treatment does not help, the surgical treatment is performed, in which way part
09:53of the thyroid gland is removed.
09:55Removing part of the thyroid gland does not eliminate the cause of the disorder.
10:00Radioactive iodine treatment.
10:03Another method of treating Graves' disease if medications are ineffective is treatment
10:08with radioactive iodine.
10:10This method is inacceptable for young people of childbearing age, but is great for older
10:15people.
10:16Radioactive iodine entering the body damages the cells of the thyroid gland and, as a result,
10:21the activity of the gland decreases.
10:23During treatment of the disease, it is necessary to reduce the amount of products rich in iodine
10:28and not to take iodized salt.
10:30Some bathing during treatment is also not recommended because there is a risk of making
10:35the treatment ineffective.
10:40Prevention of toxic diffuse gutter.
10:43Prevention of disease consists of the following measures.
10:47Lifestyle control.
10:48Health control.
10:49Timely treatment of chronic and viral infections.
10:51Very many cases can cause Graves' disease.
10:54You can be nervous and sound.
10:56Stress can only do harm.
10:59Graves' disease most often manifests itself at the age 30-40 years, which is why it is
11:05recommended to visit an endocrinologist more often at this age.
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