00:03Beta-blockers are a class of medications originally developed to treat hypertension and other
00:08cardiovascular conditions.
00:10They act as antagonists at receptors called beta-adrenergic receptors, meaning they bind
00:15to and block these receptors.
00:18Beta-adrenergic receptors are normally activated by epinephrine and norepinephrine, and their
00:23activation increases heart rate and blood pressure, among other effects.
00:27Thus, by blocking beta-adrenergic receptors, beta-blockers can decrease heart rate and
00:32blood pressure.
00:34The precise effects of beta-blockers depend on the drug in question, as there are a number
00:38of different beta-blockers with slightly different pharmacological profiles.
00:43When we experience stress or anxiety, the sympathetic nervous system causes the release of epinephrine
00:48and norepinephrine, which increase heart rate and blood pressure and contribute to other
00:52physical symptoms of anxiety.
00:53Beta-blockers can block this process and reduce physical symptoms of anxiety.
00:59While some beta-blockers can cross the blood-brain barrier and may have central nervous system
01:03effects, the benefit they provide with anxiety is thought to be primarily attributable to peripheral
01:08effects, which target the physical manifestations of anxiety.
01:12Their ability to reduce physical anxiety symptoms without impairing cognition has made beta-blockers
01:17an increasingly popular option to treat situational or performance anxiety.
01:23A number of studies have demonstrated that beta-blockers can be beneficial in reducing physical
01:27symptoms of performance anxiety experienced during situations like public speaking.
01:32The evidence regarding their benefit in regular treatment for anxiety disorders is mixed,
01:36however, and in need of more large, high-quality studies to determine effectiveness.
01:41Regardless, beta-blockers continue to be a popular option for treating physical symptoms of anxiety,
01:47in part because they are considered safer and better tolerated than some other options for anxiety
01:51treatment, like benzodiazepines.
01:52After Erfolg ener Financial
01:52Ehhh
01:59Result