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00:00For the next enzyme, the ALP is the Alkaline Phosphatase
00:07We remember that Alkaline Phosphatase is located here in the bone and also in the liver
00:15and also in many other tissues that are located in the ALP
00:21We remember that this bone is located on different types of cells
00:27The cells create this bone and the cells create this bone
00:31The cells create this bone is called osteoblast
00:36The word blast is called osteoblast
00:40Sorry, osteoblast is called osteoblast
00:48The other cells are called osteoclast
00:53We said that osteoblast is called osteoblast
00:57We said that osteoblast is called osteoblast
01:01So it will be used to be called osteoblast
01:03To reduce calcium, calcium, magnesium and magnesium
01:08So this is the Alkaline Phosphatase
01:14So it will increase during osteoblast
01:18Alkaline Phosphatase
01:19Okay, so here is the question
01:21We also don't take it in the previous slide
01:23We will see the activity with osteoblast
01:25It will increase the activity with osteoblast
01:28It will increase the activity with osteoblast
01:28The other thing is that you don't come to the world
01:30So here is what is neonatal life
01:34In the life of the children who are first to come to the world
01:37The ALP will increase the amount of weight
01:39The patient will increase the amount of weight
01:42They will increase the amount
01:45So here is the estimated cost
01:46This was probably the last result
01:53The osteoblast will increase the amount
01:56What would you do here?
01:58The amount of weight is going to increase the amount
01:59And to see what the alちょoblast will increase the amount
02:03The ALP will increase
02:05So the ALP is a double agent that is used by osteoclasts and osteoblasts.
02:09Where is osteoclasts?
02:11Where is osteoclasts?
02:11It is simply a number of diseases that are affected by the brain.
02:16And also the elderly.
02:19The increase in the age of this.
02:21This increase in the age of this.
02:24Why is this?
02:26Because it will be increased by this brain.
02:27It will increase the activity of osteoclasts.
02:29So it will increase the ALP.
02:31We are not aware of the previous ALP.
02:33So the ALP is called Alkaline Phosphatase.
02:40It is a group of enzymes.
02:43It is a group of enzymes.
02:45It is called Alkaline Phosphatase.
02:51What is this?
02:52It means that it will increase the phosphates.
02:57It will increase the A's.
02:58It will increase the destruction.
03:00In a period of time.
03:02Alkaline is called acid.
03:05Acidic is called.
03:07Alkaline Phosphatase.
03:08It is an enzyme that will increase the phosphates in a period of time.
03:12But it will increase the enzyme.
03:15Hydrolyze.
03:17Organic Phosphate.
03:18The phosphates which is organic.
03:20Organic.
03:21The material is called Organic Fosfat
03:26Organic Fosfat
03:28It will be used to use Alkaline Fosfat
03:36Hydrolyze
03:37It will add the water to the Fosfat
03:41At high pH
03:44What is high pH?
03:46We know pH
03:47The pH is above 7
03:49The pH is above 7
03:53The pH is above 7
03:55The pH is above 7
03:57The pH is above 7
04:02The pH is above 7
04:04At high pH
04:07It will turn to your Fosfat
04:09What does this enzyme say?
04:12It will turn to you hydrolyze
04:19So they are present in most tissues,
04:22It's coming in most tissues, but it's important to think about where the quality of the higher levels look at
04:29the height.
04:29But, particularly in high concentration.
04:33It's high concentration, high concentration weight, which is high concentration, but it's not all high concentration.
04:43So here I want to tell you particularly the high concentration of this enzyme is in osteoblasts of bone
04:53In these cells which are osteoblasts and osteoclasts
04:57And the cells of the hepatobiliary tract
05:02And the cells of the hepato which is hepatic and bile
05:08And the bile which is called bile
05:12What is the bile?
05:15It is because it has an enzyme that can remove the bone
05:21ALP is also found in the liver and bile
05:25Or bile duct or bile duct
05:30It is also found in the intestinal wall
05:33Which is the bone of the bone
05:37And it is found in the renal tubules
05:39We mentioned it earlier
05:40When the renal is concerned about bile ducts
05:43There is a lot of tubes
05:47So in these tubes, what is the ALP?
05:51You can say renal system in general
05:54Or bile kidney
05:55It is also found in the placenta
05:57The pregnant woman who has a baby in her body
06:00What is the placenta?
06:01With the placenta
06:03So even the placenta is found in the ALP
06:06So you can see the alkaline phosphatase
06:10But let's say that in a special way
06:12It is found in the ALP
06:14With a single plant
06:16Which is found in osteoblasts
06:19And osteoclasts
06:20In the liver
06:21In the bile
06:22In the intestine
06:23In the intestine
06:24And in the placenta
06:26Okay?
06:27I will tell you that in the adult
06:29In the adult who has been married
06:2920, 30, 40 years
06:31The plasma alkaline phosphatase is derived from where it is
06:37This plasma is called ALP
06:40Alkaline phosphatase
06:41So when I take them
06:44Alkaline phosphatase is like this
06:46This is the activity or concentration
06:49This ALP
06:51We know where it comes from
06:53From the liver
06:55From the liver
06:56From the bile
06:56From the intestine
06:57From the kidney
06:58From the kidney
06:59The placenta is only in the womb
07:00And only in the womb
07:03But the amount of blood
07:05Is found in all the cells
07:06Male and female
07:07So for this
07:08In the adult
07:09The plasma ALP
07:11From the point
07:12This is the main
07:14Is the main
07:14From any size
07:15From this
07:15The main
07:16Is the main
07:18Mainly
07:18From the bone
07:20And the bone
07:22From the bone
07:23From the bone
07:23Okay?
07:24Approximately
07:24Equal proportion
07:25What is it?
07:2650-50
07:2750%
07:29You will get from the bone
07:30And the liver
07:3150%
07:31You will get from the liver
07:32What is it?
07:34No
07:34Does it cause the number
07:35With the bone
07:36Half to the liver
07:39Since the bone
07:41It's no
07:41Is it from the blood
07:43And the liver
07:43Is found in the blood
07:45What do you say?
07:49What do you say?
07:50That ALP
07:51Is an essential
07:53For the bone
07:54and liver
07:54Why?
07:55Because the number
07:57Is particular
07:58Isocyan
07:59In the liver
08:00So
08:00So, the ALP is going to get rid of these things, and with that, we can also get rid of
08:08the ALP, so if you get rid of the ALP, then you can say that there are problems with kidney,
08:14intestinal, bile, liver, bone, bone, but at the main point, I just want to make the ball a little bit,
08:24that there are problems with the liver and the liver, so that there are problems with the liver and the
08:27liver, so that the rest is less.
08:28Correct.
08:31So, what are the reasons that could bring the plasma, alkaline phosphatase activity?
08:38What does it mean?
08:39That means that the alkaline phosphatase is less than the amount of sugar.
08:42So, I don't know about the activity, that means concentration concentration, so that concentration concentration or the amount of sugar.
08:48So, this is a physiological reason.
08:49What are the physiological reasons?
08:51So, a natural reasons.
08:53What are the natural reasons?
08:53First of all, we said that the pregnant woman has a child, and this child will get rid of the
09:01placenta or the machine.
09:02This machine uses the Alkaline Phosphatase Enzyme.
09:08Therefore, I tell you that this Alkaline Phosphatase Enzyme is combined with the placenta.
09:14It tells you that in the last trimester, in the last three months of life,
09:20in the last three months of the pregnant woman, the Alkaline Phosphatase Enzyme is combined with the circulation of the
09:27mother.
09:28It goes to the home.
09:29The circulation of the blood is combined with the blood, not the child, not the mother.
09:35So, it brings the Alpn to the home.
09:39This is the first point.
09:40This is the first physiology of the patient.
09:42First of all, during the last trimester, in the last three months of the pregnant woman,
09:49The Plasma Total Alkaline Phosphatase Activity will increase.
09:53Why?
09:54Because of the contribution of the placenta isoenzyme.
09:59Isoenzyme isoenzyme isoenzyme isoenzyme isoenzyme isoenzyme.
10:03It will help the Alp activity of the Alp activity of the mother.
10:07It will help the circulation of the mother.
10:10It's okay.
10:11It's okay.
10:12The second problem is that we remembered here.
10:16That's pretty much what happens!
10:18What time will the activity of the mother?
10:18It will increase the ALP activity in the place of osteoplasts and osteoclasts.
10:24We told you about osteoplasts if you have an Osteoplasts.
10:27You are getting an absentee for the adult and a puppy.
10:31It will increase theals.
10:32The osteoclasts is about the elder who will in the early age of the elderly
10:37So this is the preterm infant
10:42The preterm infant
10:43The children who are vulnerable
10:44They are less than 9 years
10:47That's what they are
10:49Total Plasma ALP
10:51They are very small
10:54They are very small
10:56They are very small
10:56From the upper reference limit
11:00In the adult
11:02ALP
11:05The alkaline
11:07Phosphatase
11:09From the adult 1 to 2
11:12So this is the upper limit
11:13This is the upper limit
11:15For the preterm infant
11:17This is what happens
11:185 of the upper limit
11:21That means 10
11:23Because they are very small
11:24This is very simple
11:27And consists predominantly
11:29Of the bone and the eye zone
11:31Why is this ALP
11:31Because it is simply
11:33At the point of view
11:35This ALP
11:37It is not the upper limit
11:40ALP is not the upper limit
11:42ALP is not the upper limit
11:43Because it is not the upper limit
11:46This is the preterm infant
11:47Also in the children
11:52The total activity of the enzyme
11:56But it is not the upper limit
11:59It is not the upper limit
12:00It is not the upper limit
12:04But it is not the upper limit
12:05It is not the upper limit
12:06During what?
12:08During the pubertal bone growth spurt
12:10At the point of view
12:12At the point of view
12:14At the point of view
12:16At the point of view
12:16At the point of view
12:17So what will increase
12:19With the lower limit
12:19With the lower limit
12:20And this is also
12:21When we remember
12:22We remember here
12:23We also said
12:24With the pubertal bone
12:26It will increase
12:27Here I have
12:27It will increase
12:28With the lower limit
12:29Okay?
12:30So it says
12:31There is a gradual increase
12:33In the proportion
12:35Of the liver ALP
12:36With age
12:38So what will happen
12:39Here is what will happen
12:40This increase
12:41What is bone growth?
12:42This increase
12:43This increase
12:43In the upper limit
12:45In the upper limit
12:46From the upper limit
12:47From the upper limit
12:47ALP of the bone
12:48ALP isoenzyme
12:51Okay?
12:52With the liver
12:53Is it possible to increase
12:53In the upper limit
12:54In the upper limit
12:55Yes?
12:56It also says
12:57ALP
12:58Is not the liver
12:59It is possible to increase
13:00You can increase
13:03With the liver
13:04In the upper limit
13:04With age
13:05So if all you become
13:06Away from the upper limit
13:10ALP
13:10You don't have to increase
13:11ALP
13:12With the liver
13:13We also recall
13:15You know
13:15What is the elderly
13:16In the upper limit
13:17Is increase
13:18At the upper limit
13:19It will increase
13:20With the arthritis
13:20And the posterior limit
13:23In the upper limit
13:23Also
13:23At the upper limit
13:27Please increase
13:28In the upper limit
13:31This is physiological, so it's not natural, you're a child, you're a child, you're a child, you're a child, you're
13:38a child, you're a child, you're a child, you're a child, you're a child.
13:39This is ALP, which is not a child, but it's natural.
13:42It's a pathological cause, because of the disease, which is like bone disease, as I remember, ALP is in bone,
13:56and liver, even in smoothness, even in gastrointestinal tract.
14:02So any problem with bone, any problem with liver, any problem with JT, any problem with the rest of the
14:07disease, which is under ALP, will apply to ALP.
14:11So for example, bone, BALP is B.
14:14So if I have bone disease, for example, rickets, what is it?
14:19The rickets are the vitamin D.
14:23Where are the vitamin D?
14:26Where are the children?
14:27Where are the children?
14:28Where are the children?
14:29Or osteomalacia, which is also the vitamin D.
14:34But here we are in adult.
14:36This is what we do, of course.
14:38This is a disease.
14:40It means that this bone will break down, because there is no vitamin D to burn.
14:46You know the milk?
14:48Why is vitamin D and calcium?
14:50So when there is vitamin D, the bone will break down.
14:54So it's in the disease.
14:55It's in the disease.
14:56And osteomalacia is in the disease.
14:57The liver, BALP, B.
14:59So the liver disease, also leads to ALP.
15:04What is the most important thing?
15:06What is the most important thing here?
15:09The liver has a network with BALP.
15:15With BALP.
15:15It has a network with BALP.
15:17With BALP.
15:18With BALP.
15:18So the BALP is also coming from it.
15:20So it is a network with BALP.
15:22If you have a networked network within these channels.
15:28With BALP.
15:30Or a networked network from outside.
15:31You have the most important thing and not get centered on it.
15:34What should I do with B?
15:38So if this is why our desire to keep D number then it is to absorb it.
15:43So the aberrestrial cells will burn like thestream.
15:43Then what do I tell you?
15:44If you recover from the cells from outside.
15:45Which is intra indirectly oял.
15:53Then in 10 to allows a mother for a saying that if una started boosting the cells in the эп.
15:56How heartache, your respiratory cells are now rooted in the voll society.
15:56So make a disease increase from outside.
15:56So extra raises all that.
15:59This means that the acid is only because of the structure from outside
16:03So this will lead to prevent the acid and the cells from there
16:07So the alkaline phosphatase
16:11Here we say what?
16:13Intra-hepatic or extra-hepatic cholestasis
16:17Stasis means stasis means thabat
16:20Choly is biol
16:23So as we remember the biol
16:26The biol is stasis
16:29So you start to get to the liver and get to the liver
16:34Bowel or GIT
16:36The bowel is a maltic
16:38The bowel is a maltic
16:40B-ALP
16:42Inflammatory bowel disease
16:44The bowel is an maltic
16:48The gut is a maltic
16:50This is ALP isoenzyme
16:52This will increase in the condition of the disease
16:56In the condition of the disease
16:59The ulcerative colitis
17:00The ulcerative colitis
17:01The ulcerative colitis
17:11The ulcerative colitis
17:22They are also the cure
17:24This may matter for him
17:24To prevent the causes as the repair
17:30Then the ulcerative colitis
17:34And the umber
17:34The ulcerative colitis
17:52or in the cells of the cells and the cells of the cells
17:56Okay?
17:57So this is bone or level involvement
18:00So it's going to be a malignancy
18:02or direct tumor production
18:04The tumor that has cells of the cells is able to remove the ALP
18:08Here is a point that the placental isoenzyme
18:13which is called ALP
18:15is the alkaline phosphatase
18:17and the placenta
18:19It doesn't mean the placenta
18:22What does the placenta mean?
18:24It doesn't mean the placenta to the child
18:27but it can be used to the mother
18:29So it doesn't mean the placenta to the child
18:31and is therefore not detectable in the plasma of the newborn infant
18:36So you can find ALP
18:39for the placenta to the infant
18:41Why?
18:42It doesn't mean the placenta to the child
18:43It doesn't mean the mother and the child
18:45Okay?
18:46That's the first point
18:47The second point
18:48I tell you
18:49You have alkaline phosphatase
18:51for the liver
18:52alkaline phosphatase
18:54asoenzyme of the liver
18:56I tell you
18:56If this is a damage to the liver
18:58it will cause you alkaline phosphatase
19:01I can say
19:02Okay, this alkaline phosphatase
19:04is located in bone
19:05or in GIT
19:06or in other places
19:08It's not only the liver
19:10but it's a disease in other places
19:11I tell you
19:41this is sensitive
19:44but it's also
19:45It's also
19:45concomitantly
19:47meaning
19:47so
19:48and
19:49with the ALP
19:51without the liver
19:52disorder
19:53I have a disease in the liver
19:55Okay?
19:55So you can
20:26you can
20:26you can
20:26you can
20:29you can
20:29you can
20:29you can
20:30you can
20:33stage제를
20:33need
20:34also
20:34only
20:34remember father
20:36who
20:37was
20:38she
20:39saw
20:40She
20:40her
20:41the
20:50enzyme
20:51Phosphatase enzyme
20:53Lever has a special enzyme
20:55I can't use it
20:56But I don't use it
20:57With the liver disease
20:58RBC
20:59Lactyl dehydrogenase
21:00Is a special enzyme
21:01Pancreas
21:01Is a special enzyme
21:02So ACP
21:05Acidic Phosphatase
21:07Is used to use
21:08It's not used to use
21:09It's used to use
21:10Prostate
21:12Prostate
21:14Prostate cancer
21:15Prostate cancer
21:18Prostate cancer
21:19It's used to use
21:20A high acid
21:24Phosphatase
21:25We can use it
21:26It's a prostate cancer
21:29But what's the problem?
21:31ACP
21:32Is there all these
21:33So it's not specific
21:35So they're not used to use
21:38What do you use?
21:40They use
21:45Prostate
21:46Antigen
21:51Protein
21:51Protein
21:52Prostate
21:53It's not specific
21:54Prostate
21:55If it's a patient
21:56If it's a patient
21:56If it's a patient
21:57If it's a patient
21:57If it's a patient
21:57Then we'll read
22:01Acid Phosphatase
22:02Is found
22:03In the cells
22:04Of the prostate
22:05Prostate
22:09Of上
22:15But the main indication for the estimation
22:21The main reason is to remove the acid phosphatase
22:28What was it that was previously?
22:30It was to help us to remove the prostate cancer or prostate carcinoma
22:36Prostatic prostate
22:38And to monitor the treatment
22:43What is it that is to remove the treatment?
22:45It also to remove the treatment
22:48If you were to remove the treatment
22:49Now I have prostate cancer
22:52I found the ACP
22:56Acidic phosphatase
22:58For example, I found the treatment
23:01I found the treatment
23:04If I found the ACP
23:06If I found the ACP
23:06It was 3, 4, 2
23:07I found the treatment
23:09If I found the treatment
23:10I found the treatment
23:11I found the treatment
23:13So this is not just the treatment
23:15I found the treatment
23:16I found the treatment
23:17Is the treatment
23:18Is the treatment
23:18Or not?
23:20Good
23:21Estimation
23:22The ACP
23:25Has been largely replaced
23:27We started
23:28In a new
23:29In a new
23:31In a new
23:33Prostate
23:35The Antigene
23:36Prostate
23:37The Antigene
23:38The Antigene
23:39Is specific
23:39This is the Antigene
23:41Or the Protein
23:41The Prostate
23:43We began
23:43This is better
23:44It's not only the Prostate
23:47So this is the best
23:48So this PSA or Prostate Sensitive Antigene
23:54This protein is derived from the prostate
23:58If you say prostate is specific antigen
24:00It's a protein with prostate
24:01Okay?
24:03So this PSA or Prostate Specific Antigene
24:07This is more specific
24:09It means that it is more sensitive and more sensitive
24:14For the treatment
24:15And that is also following the treatment
24:19With prostate cancer
24:22Okay?
24:24With prostate cancer
24:25What do you say?
24:27This PSA
24:29The Prostate Specific Antigene
24:32Has essentially rendered
24:35It means that it reduced the importance of the Plasma Acid Phosphatase
24:40It reduced it completely
24:43Absolute in the diagnosis and the management of the prostate carcinoma
24:47It's almost impossible for this ACP
24:51With the treatment and treatment of prostate cancer
24:55So this is the result
24:57So this is the result
24:59Now we don't use it
24:59We only use Prostate Specific Antigene
25:03Okay?
25:03This acid phosphatase
25:06It's always available in the liver
25:08It's also available in the RBC
25:09And the prostate
25:10It's also available in the isoenzymes
25:11It's also available in the isoenzymes
25:11Depending on where it is
25:12So it says
25:15The release of ACP
25:18From blood cells in the vitro
25:21I have to read it
25:22What do you say here?
25:24You remember
25:26We can say
25:27Blood vessels
25:29And these are blood cells
25:30Blood cells
25:31Okay?
25:33And you will have a needle
25:36And you will take it
25:38From it
25:42You will take it
25:44You will take it
25:46You will take it
25:47You will take it
26:00What do you say here?
26:00You know
26:01What is ACP?
26:03You know
26:03You can say
26:04That the problem
26:04Is it
26:05From the RBC
26:10So the RBC
26:13Is good
26:13And you can save it
26:18The blood with the blood with the blood with the blood with the blood with the ACP
26:23This ACP comes out
26:25Even if you went through a correct way
26:28It doesn't have any problem
26:30This is a correct way 100%
26:32So the ACP comes out a little bit
26:34Why do you know?
26:35It comes out of the ACP
26:38This is a problem if it's not a problem
26:40This is a problem
26:42Why?
26:43Because this person has prostate cancer
26:46So the ACP comes out of the ACP
26:53Because the ACP comes out of the liver
26:54The ACP comes out of the liver
26:56The ACP comes out of the RBC
26:58The ACP comes out of the prostate
27:01And this is like that
27:04So when I go to the total ACP
27:10I go to the elevated
27:12Why is it so good?
27:13Because the RBC took out the Acidic Phosphatease Inzyme
27:17For it comes out of the outside
27:18So it's not a problem
27:20I was scared and I'm scared
27:20I'm scared that this prostate is the prostate
27:22So you say what do you do?
27:23It comes out of the Isoenzyme
27:25It comes out of the Isoenzyme
27:27You'll find out that the Isoenzyme
27:29You'll find out that it all came out of the RBC
27:32It's not from prostate or liver
27:35or from the rest of the cells
27:37So what are you doing here?
27:39You have to relax
27:41There is a question here
27:42What do I am going to do this
27:45and increase the Iso Enzyme?
27:47I tell you that you are going to take
27:49two eyes
27:49You are going to take two eyes
27:52This is the eyes number 1
27:55and this is the eyes number 2
27:57I took two eyes
28:00I took two eyes
28:01ACP
28:01It came out from the RBC
28:043
28:07ACP
28:08Do you want to confirm
28:09that ACP
28:11is the blood of the blood of the blood of the blood
28:13as it is the ACP
28:15is going to come quickly or not
28:17if this ACP is not for prostate
28:21so you have prostate cancer
28:23What do you do?
28:24What do you do?
28:24I tell you
28:25that you are going to take one
28:26some Alpine
28:29Tartrate
28:31the
28:31immunitis
28:32this will make it
28:34you need to make it
28:37on the main figure
28:40so Sen
28:41this Tartrate
28:43is justhooing
28:44the Is impatient
28:45what's going on?
28:47It activates
28:48it
28:48it
28:49before
28:51Okay?
28:52So, that is definitely
28:56Because you are in the end of this
28:58You will be able to get the total acid phosphate
29:03What is the total?
29:04What is the total?
29:05What is the total?
29:05What is the total?
29:05What is the RBC?
29:06What is the prostate?
29:08So, you will be able to get the ACP
29:13So, you will be able to get the acid phosphate enzyme
29:17This is not what you are going to do
29:19You will know that the acid phosphate enzyme is 10
29:25When I made the Territrate
29:26It was 5
29:28So, you know what?
29:30That 5 of the activity of this enzyme
29:34Why did it go?
29:36Because the prostate is broken
29:37Okay?
29:39So, I have a very high number of prostate isoenzyme
29:46In this sample
29:49And it was not RBC
29:51Because the Territrate is working only on prostate
29:54And not RBC
29:56So, when it was 10
29:57It was 5
29:58It was 5
29:59It was 5
30:00It was 5
30:00It was not the prostate
30:02That was the Territrate
30:04So, if I know the activity
30:08Concentration
30:08But the
30:09It was 5
30:11It was 5
30:12It was 5
30:13It was 5
30:14So, I have a cancer
30:17If I have cancer
30:18If I have cancer
30:32Okay?
30:34May occur even
30:36Even
30:37It could also happen
30:38Where?
30:39With the unhemolized samples
30:42The cells that are not
30:44That are not the blood
30:45That is, the blood
30:46That is, the blood
30:46That is, the blood
30:47That is not the blood
30:48With that, it will be
30:50Acidic phosphatase
30:52Okay?
30:53So, it says
30:54And many methods
30:55And many methods
30:55And many methods
30:56And many methods
30:58Have been devised
31:00In an attempt
31:00To measure only
31:02The prostatic fraction
31:03So, we have here
31:04We have to do
31:05The prostatic fraction
31:06On what?
31:08On what?
31:08On the mode
31:08To only
31:09The prostatic fraction
31:12Acidic phosphatase
31:13Isoyenzyme
31:14Isoyenzyme
31:15I see if I have prostate cancer
31:17If I don't have
31:18Why?
31:18Why is this problem?
31:19If you think about the total
31:21The total is high
31:22Why is it high?
31:24Because the ACP
31:25Is always high
31:26So, the ACP
31:27Is always high
31:28So, the ACP
31:28Is always high
31:29Okay?
31:30I'm sorry
31:31I'm sorry
31:31I'm sorry
31:32I'm sorry
31:32I'm sorry
31:32I'm sorry
31:33Is this ACP
31:35Prostatic
31:36Or not
31:37Is this ACP
31:38Prostatic
31:38We have done
31:39One method
31:43One method
31:44One method
31:46Makes use of the fact
31:48What?
31:49What?
31:50What?
31:51What?
31:51What?
31:53What?
31:53What?
31:53The ACP
31:57Prostatic
31:58Acidic Phosphate
31:59That means
32:00Prostatic
32:00Acidic Phosphate
32:01That means
32:02The ACP
32:03That means
32:05What?
32:07What?
32:11What?
32:12With and without
32:14The addition
32:14Of the LTR
32:15Trate
32:16Sample
32:16It makes it
32:17LTR
32:18And without
32:20The addition
32:22Of the LTR
32:22Trate
32:23The LTR
32:25The LTR
32:34And it's
32:36What?
32:40From the LTR
32:42The LTR
32:42This one
32:42That one
32:42It's
32:42The LTR
32:44This one
32:44From the LTR
32:45The LTR
32:53The Territrate Labial Fraction
32:58The Isoeinzyme
33:01The Isoeinzyme
33:02The Territrate
33:04The Prostatic ACP
33:08The L Territrate
33:12The Prostatic Acp
33:17The Prostatic Acp
33:20The Prostatic Acp
33:23The Prostatic Acp
33:23Whether You're included
33:31The Prostatic Acp
33:41As if it starts to expand
33:43blue my belly
33:44Intestine
33:46In the deep brain
33:48So you call this
33:50What's behind the brain?
33:52It's the deep brain
33:53This is in the deep brain
33:56And also in your mouth
33:58That means
34:00The saliva
34:02The saliva
34:03Do you know what the benefit of the brain
34:05In the small intestine
34:07The pancreas
34:08It uses
34:12Amylase
34:14To the small intestine
34:15With the saliva
34:19This saliva
34:20Alpha Amylase
34:22What's the benefit of the brain?
34:24The benefit of the brain
34:27Carbohydrate
34:28Carbohydrate
34:30Carbohydrate
34:31So we're going to eat
34:33The potato
34:35This potato
34:37It's starch
34:39It's starch
34:40Mole
34:42Poly
34:44Syδ
34:45Poly
34:45Poly
34:46Poly
34:46Poly
34:47Poly
34:47Poly
34:47Poly
34:47Poly
34:50Theum
35:13The alpha amylase is a polysaccharide to small groups, which is called Maltose, which is called Maltose.
35:45The alpha amylase is also called Maltose, which is called Maltose, which is called Maltose.
35:58The alpha amylase is also called Maltose, which is called Maltose, which is called Maltose, which is called Maltose, which
36:09is called Maltose.
36:16The glucose is called Maltose, which is called Maltose, which is called Maltose, which is called Maltose.
36:43that is 45 kilodaltons
36:46why do these raises the
36:48one because they don't suck
36:49we're telling them
36:51so, the weight and the increase
36:53its weight for the plast 게�рат
36:57again, the reduction
36:59what is the spiciest Стób
37:02the Orchest
37:04who is located in Leary
37:05or who is located in theuela
37:07like using Corporate your
37:08in the states
37:09it is basically
37:10which bacteria
37:10Carbohydrate
37:13And glycogen
37:15Glycogen
37:16Where is it?
37:17Where is it?
37:20Maltose
37:22Polysaccharide
37:23To Dysaccharide
37:26Good
37:28It's present at
37:30With a high level
37:32In pancreatic juice
37:35Where is it?
37:36In pancreatic juice
37:37When pancreatic juice
37:40This is a high level
37:44In pancreatic juice
37:47In pancreatic juice
37:49In pancreatic juice
37:50In pancreatic juice
37:50In pancreatic juice
37:51And may be extracted from other tissues
37:54In other tissues
37:56In other tissues
37:58What is other than liver?
38:01The gonads
38:02The phallopian tube
38:06What is the phallopian tube?
38:08This is the female
38:10What is it?
38:12This tube
38:14This tube is near
38:16The ovary
38:17We have to be able to do the embryo
38:20This ovary
38:21This is the embryo
38:22Where is it?
38:25To the phallopian tube
38:27This is the phallopian tube
38:36Amylase
38:37The skeletal muscle
38:39And the adipose tissue
38:41Amylase
38:42Now I want to know
38:45What are the reasons
38:46What are the reasons
38:48To restore the plasma amylase activity?
38:51Okay?
38:53The plasma amylase activity
38:56We are going to divide it
38:59Marked increase
39:02This means
39:03Plazma amylase
39:04Where is it?
39:06This is a way to restore the path
39:09This means
39:11If it were the upper reference limit
39:14It would be a 2
39:15It would be a 2
39:17To accommodate 5
39:17To 10
39:18It would be 2
39:24The second increase is moderate to slight increase, which is less than 5% of the upper reference limit.
39:39What are the reasons for the marked increase?
39:42The second increase is acute pancreatitis.
39:48The second increase is severe glomerular impairment.
39:58We said kidney or chileamaltic, if I increase these cells, is what happens?
40:06What is it?
40:07It is a tubule.
40:10This area will come to blood vessels.
40:14This area will come to blood vessels.
40:16This area is a area that will fall into the blood vessels.
40:19This area is called glomerular area.
40:24The area is glomerular area.
40:27If you have a problem with the glomerular area, there is a severe glomerular impairment.
40:35It will also increase the amylase.
40:37What is the difference?
40:41Because the body will not be able to get rid of the amylase.
40:45It will not be able to do the filtering and get rid of the amylase.
40:49The amylase is located in the blood.
40:51It increases the number.
40:54Thyobetic ketocytocytosis is also the sugar molecule.
40:57The DKA is also the kidney.
40:59The theobetic ketocytocytosis.
41:01Of course, the ketocytocytosis is a problem of it.
41:03It is a problem of the heroin opioidQuezosis.
41:09It is a problem of the cancer cells.
41:10It doesn't depend on sugar, it depends on the ketone body.
41:14It depends upon the ketone body as an individual.
41:16What happens in the cells? Uninflammatory.
41:21So it is called ketocidosis. This is also a disease called amylase.
41:29What do they have? Perforated peptic ulcer.
41:32These are the nose and are the lung.
41:39The neck or the small intestine has its name...
41:45I don't want to tell you about it, but this is the brain of the brain
41:49If it happened to the brain, this is an ulcer, so it is called peptic ulcer
41:55If the peptic ulcer fell to the level of the brain
42:00What happened?
42:02It broke the brain, so the brain broke the whole body to the outside
42:08What's going on here?
42:12The brain broke the brain in this area
42:15The brain broke the brain in this area
42:18When it comes to this area, there is an ulcer in the inside
42:22It is called lesser sac
42:27It means cheese or ulcer in the inside
42:30This is the ulcer in the inside
42:32This is the ulcer in the inside
42:36This is the ulcer in the inside
42:38What do you say?
42:42Perforated peptic ulcer
42:44This is the ulcer in the inside
42:46What do you do?
42:48Especially if there is perforation into the lesser sac
43:12Acute abdominal disorder
43:15So we are talking about abdominal disorder
43:19Paincuiasi is part of the muscle
43:22About the muscle
43:23That one
43:23Is part of the muscle
43:24This also diz way
43:26Okay, ketosidosis
43:29Or glomerular impure
43:31It's also a part of the abdomen.
43:33So the other diseases that happen in the body can also lead to moderate.
43:39But what should it be? It has to be a small disease.
43:42For example, perforated peptic ulcer.
43:45Now I can say that I have a perforated peptic ulcer.
43:48But what is it?
43:50It doesn't have a strong or strong condition.
43:52It can lead to the lesser sac.
43:53It can lead to the lesser sac.
43:56It can also lead to the amylase.
43:58Acute cholecystitis.
44:03It's called the gallbladder.
44:09It's close to the liver.
44:12It's called the gallbladder.
44:16It's responsible for the brain cells.
44:20It also leads to the amylase.
44:24He says this is close to the pancreas.
44:29The pancreas is close to the pancreas.
44:30Can you do the pancreas?
44:33Intestinal obstruction.
44:35It means that you eat.
44:38And these are the amylase.
44:40The pancreas will bring the amylase to the amylase.
44:45So the amylase will bring the amylase to the amylase.
44:54So it will also increase due to the intestinal obstruction.
44:59Good.
45:00Abdominal trauma.
45:01The damage on the bone.
45:02The damage on the bone.
45:04The damage on the bone.
45:04The damage on the bone.
45:05The pancreas will bring the amylase to the amylase.
45:09The amylase will bring the amylase to the amylase to the amylase.
45:22In some situations where you are going, these types of chains will turn up until the blood pressure rebound in
45:32using the amylase.
45:38So the amylaseي will do non- sól 갑자기 the amylase perché.
45:39So the scientist problems see the breast the amylase in the amylase to the amylase.
45:40Cardgroup cand Nature is Millennials from them.
45:49Now we're going to the last slide, which is the last condition.
45:53I'll tell you that sometimes this amylase, this is the blood vessels,
46:01it comes to amylase.
46:04I'll tell you that this amylase is used in proteins,
46:08so it increases the amylase to a very large size.
46:13We remember that it was about 45.
46:15It becomes more than 200.
46:19What is the problem?
46:21The problem is that when you go to kidney, the kidney is not able to get rid of the kidney,
46:25because the kidney is not able to get rid of the kidney.
46:29You also have to eat the blood.
46:31So this is the case called macros,
46:36the word macros means huge in the size.
46:38It's about 45 to 200.
46:41You can have an amylase of amylase,
46:44it is very low.
46:46It is called an amylase of amylase.
46:47It means blood.
46:48It's called an amylase of amylase.
46:56He will tell you because of what? Because of the low renal excretion, the kidney can not be able to
47:03get rid of this enzyme
47:05Low renal excretion of what? Of macro enzyme form to this macro enzyme
47:12This amylase became macro, it was bigger in the size of it, so he will not be able to get
47:18rid of it
47:19Despite normal glomerular function, although the glomerular function of it, which is the glomerular function of it, the glomerular function
47:29of the glomerular function of it, is not a problem
47:35With that, I can't afford it, but the problem is that this enzyme is very big
47:41The condition is symptomless, and it is thought, and it is thought, and why is this amylase?
47:51He thinks that this enzyme is connected to IgA antibody, which is protein called IgA
48:01This is protein protein, which is called IgA, IgM, IgG
48:09But I think that this is connected to IgA, so it is greater in the size of it, so it
48:12is connected to the enzyme of it
48:14It is connected to the enzyme of it, and it is connected to the enzyme of it
48:17This is the same thing, so if I tell you that when it is connected to IgA, what is it?
48:22It's connected to IgA, so it is connected to IgA, and the weight is not combined to 270, rather than
48:2745
48:28So this is a harmless condition, which is the case, which is harmless
48:33It is not a problem, it is not a problem
48:36It is not a problem
48:37Maybe confused, so someone can numb it to it
48:39And other causes of the hypermyelizemia
48:46Hyperamylase, amylase, which is the dam, so it is a dam, amylase
48:49He could be able to get a muscle
48:51I could say that hyperamylalcemia
48:53Or macroamylalcemia
48:55Is it these issues
48:59Are there any person
49:00If there is no problem
49:02And there is no problem
49:06There's no problem
49:07So, the person will get a muscle
49:09Why? Because the treatment
49:11is going to be a increase
49:13in the amylase
49:15He doesn't say that this increase
49:16What?
49:19that it is related to the IgA.
49:21So we need to stop doing several tests
49:24so we can get to the Echid
49:27So finally, we finished clinical enzymology
49:32clinical enzymology
49:33It is an important thing
49:34which is all important
49:35and is all about clinical enzymology
49:39so all of it will be important
49:41and I appreciate you all.

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