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In this video, Dr. Kevin Lowe explains what albumin does, why a low albumin level may appear on your lab report, and what that result could be telling you about your health.
Albumin is an important protein made by the liver. It helps keep fluid inside the blood vessels, carries certain medicines and hormones, and supports many normal body functions. A low albumin result is not always an emergency, but it can sometimes point to an underlying problem.
You will learn about the main causes of low albumin, including:
• Liver disease
• Kidney disease and protein loss in the urine
• Inflammation or infection
• Heart failure and fluid overload
• Poor nutrition
• Protein loss from the intestines, burns, or wounds
The video also explains why low albumin does not always mean malnutrition, why doctors usually treat the cause rather than the number itself, and which questions you should ask when albumin is below the normal range.
A low albumin level is not a diagnosis by itself. It is a clue that must be understood together with your symptoms, medical history, and other laboratory results.
This video is for education only and is not a substitute for medical advice, diagnosis, or treatment. Speak with your healthcare professional about your own blood test results.
Transcript
00:00Your blood test shows that your albumin is low,
00:02but your doctor seems concerned more about other results.
00:07They did not prescribe any medication,
00:09and they may not even have mentioned it to you.
00:13So, should you just ignore it?
00:15Well, not so fast.
00:18A low albumin level is usually not an emergency by itself.
00:23It is not like a dangerously high potassium level
00:26that could quickly affect your heart.
00:29Albumin is different.
00:30It is more like a warning light on the dashboard of your car.
00:35The light may not tell you exactly what is wrong,
00:39but it tells you that something might need to be checked.
00:43So, what exactly is albumin?
00:46Albumin is the most common protein in the liquid part of your blood.
00:53It is made by your liver, and it has several important jobs.
00:58One of its main jobs is to help keep fluid inside the blood vessels.
01:05Think of albumin like a sponge that helps hold water in your bloodstream.
01:11When albumin becomes very low,
01:15more fluid may move out of the blood vessels and collect in the tissues.
01:22This can cause swelling in the legs, feet, or other parts of the body.
01:27In some illnesses, fluid may collect in the abdomen.
01:33In heart failure, fluid may also build up in the legs, in the lungs,
01:40and breathing may be difficult.
01:43Low albumin is usually not the only reason this happens,
01:48but it can certainly make the problem worse.
01:52Albumin also helps protect the thin lining inside your blood vessels.
01:58This lining helps control how much fluid and protein moves in and out of the bloodstream.
02:07Scientists are still studying exactly how the albumin affects this lining,
02:12but we know albumin plays a role in keeping blood vessels working normally.
02:19Albumin also carries many substances through the blood.
02:25It carries hormones, vitamins, minerals, and some medications.
02:32Many medications attach themselves to albumin as they travel through the bloodstream.
02:39When albumin is very low,
02:41more of the medication may remain unattached or free in the blood.
02:47For certain medications,
02:49this can affect how well the medication works
02:52or increase the chance of side effects.
02:56But this does not happen with every medication.
03:00It depends on the drug and how low the albumin level is.
03:06Some water pills may also work less efficiently in people with very low albumin,
03:14although this does not happen in every patient.
03:18Now, you may have heard that low albumin means you are not eating enough protein.
03:24Sometimes, poor nutrition can play a part,
03:29especially when it is severe or has lasted for a long time.
03:35But albumin is not simply in nutrition tests.
03:40A person may have a low albumin level even if they are eating enough.
03:47Inflammation, infection, liver disease, kidney disease,
03:52and extra fluid in the body can all lower the albumin.
03:58That is why doctors should not use albumin alone
04:01to decide whether someone is malnourished.
04:05Low albumin is also common during certain illnesses.
04:10The albumin can be low if there is a serious illness.
04:13When the body is fighting an infection, healing from surgery,
04:18or dealing with inflammation, albumin often falls.
04:24Albumin is called a negative acute phase reactant.
04:28That is a complicated way of saying that the albumin level often drops
04:33when the body is under stress.
04:35In hospitalized patients, a very low or falling albumin level
04:39may be a sign that the illness is more serious.
04:43It cannot tell doctors exactly what will happen,
04:46and it cannot be used alone to predict someone's recovery.
04:50But it can be one clue that helps doctors understand
04:54how sick a patient may be.
04:57So what causes albumin to become low?
05:00There are five main reasons.
05:02Number one, the liver is making less albumin.
05:07Albumin is made in the liver.
05:09If the liver is badly damaged,
05:12it may not be able to make enough albumin.
05:15This can happen in advanced liver disease,
05:18including severe cirrhosis.
05:21Severe starvation or long-term protein shortages
05:25may also lower albumin production,
05:28especially when another illness is present.
05:31Number two, albumin is being lost through the kidneys.
05:37Healthy kidneys normally keep albumin in the bloodstream.
05:42But certain kidney diseases allow large amounts of albumin
05:46to leak into the urine.
05:49When this happens,
05:51the albumin level in the blood may fall,
05:54and the patient may develop swelling.
05:56A urine test can help show whether this is happening.
06:03Number three,
06:05albumin is being lost somewhere else.
06:08Albumin can also be lost through the intestines.
06:13Certain bowel diseases
06:14cause protein to leak into the digestive system
06:18instead of staying in the blood.
06:22Large burns,
06:24severe skin problems,
06:26open wounds,
06:28and heavy drainage from wounds
06:30can also cause protein loss.
06:33Number four,
06:35inflammation causes albumin
06:38to leave the bloodstream.
06:40During serious inflammation,
06:43infection,
06:44burns,
06:45surgery,
06:46or injury,
06:48blood vessels may become more leaky.
06:52Albumin can then
06:53move out of the bloodstream
06:55and into the surrounding tissues.
07:00The albumin may still be somewhere in the body,
07:04but less of it is in the blood
07:07where the test measures it.
07:10Number five,
07:12too much fluid dilutes the albumin.
07:16Sometimes,
07:18the body holds on to too much water.
07:20This may happen in heart failure,
07:24kidney disease,
07:25liver disease,
07:27or after receiving large amounts of fluids
07:30through an IV.
07:32The extra water
07:33can dilute the albumin in the blood,
07:36making the level appear lower.
07:40Serious illnesses may also cause
07:43albumin to break down more quickly than usual.
07:47So,
07:48what should you ask when your albumin is low?
07:52First,
07:53you want to know,
07:54how low is it?
07:56A slightly low albumin level
07:58may mean something very different
08:01from a severely low level.
08:04Second,
08:05is this the first layer result
08:07or has it been low for a long time?
08:11Third,
08:13is the albumin continuing to fall?
08:16Fourth,
08:18is protein leaking into the urine
08:21or being lost through the intestines?
08:24And finally,
08:26are there any signs of liver disease,
08:29kidney disease,
08:31inflammation,
08:32infection,
08:33or fluid buildup?
08:36The main point is this.
08:39Low albumin
08:40is not a disease by itself.
08:43It does not always mean
08:45you're malnourished.
08:46And it does not always mean
08:48you need albumin treatment.
08:51That it should not
08:52automatically be ignored.
08:55A low albumin level
08:57may be an important clue
08:59that something else is going on
09:02inside the body.
09:02I hope you found this useful.
09:05If you did,
09:06like and share the video
09:07with your friends and family.
09:08You can support this channel
09:10by subscribing.
09:12Until the next video,
09:13stay healthy
09:14and stay safe.
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