00:00Hello there! Welcome to another episode of Putting Dr G on the Spot in the month of February
00:06when we're celebrating Valentine's Day yesterday. So during the whole month of February, we're
00:13talking about the love pills. We started off talking about the various types of the blue pills
00:18and also various types of different pharmacokinetics. And this time,
00:23we're going to ask whether it is possible to have the love pills on a daily basis.
00:35In fact, there are two types of PDE5 inhibitors. One of them is short-acting, the other one is long
00:42-acting.
00:42When you think about long-acting, which actually have a half-life of about 36 hours, will this be
00:49a medicine that you can take on daily basis? In fact, there is a slower dose of PDE5 inhibitors
00:57called Tadalafil 5mg that is taken on a daily basis. Why is that an advantage? Some people
01:04actually think that taking this on a daily basis actually will enhance the blood flow to the penis
01:11as compared to on demand. So that reduces the peak and trough of the actual medication if you take the
01:19drug on demand. So for patients, that creates a lot of spontaneity. However, there's a lot more than
01:26that. If you take daily dose of PDE5 inhibitors, then you realize that it also helps with other medical
01:33conditions. For example, benign prostatic hyperplasia. When the prostate becomes too big, by taking 5mg of
01:43PDE5 inhibitors, you realize that the urine flow is stronger and frequency and urgency of urine is also
01:51less. There are two other medical conditions also being used. For example, pulmonary artery hypertension.
01:59So this is a condition where the constriction of the artery to the lungs causes tiredness
02:05and also shortness of breath. When you take this, the fusions of the lung is increased and the energy
02:11level goes up. And lastly, there's a condition called Reynolds disease where the arteries to the fingers
02:18and also end organ becomes less. By taking this medication, it enhances the blood flow for people
02:24who suffer from Reynolds conditions. One last condition actually is called penile rehabilitation.
02:31If a patient is to undergo a radical prostatectomy for prostate cancer, for example, then by taking the
02:38medication three months before the actual surgery, it will reduce the risk of somebody having erectile
02:45dysfunction after the operation. For next week, we would have gone into the year of the horse and then
02:53therefore we're going to talk about something else which is a myth busters about all the love
03:00pills. And you need to stay tuned for next week's putting Dr. G on the spot.
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