King learns about latest cancer research during NI visit

Royal Family Channel

The King has learnt about groundbreaking research into cancer therapies as he and the Queen continued their visit to Northern Ireland. Charles visited Ulster University’s campus in Coleraine where he was told about new stimulus-responsive therapeutic technology that is being used to target tumours. The technology uses microbubbles to deliver therapies. The King was shown three stages of the current research, from the manufacture of microbubbles to their activation. Report by Covellm. Like us on Facebook at http://www.facebook.com/itn and follow us on Twitter at http://twitter.com/itn

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00:30of the globe, ruptures the bubbles,

00:32and releases the gold in a targeted manner.

00:34And also,

00:35Mr. Secretary General,

00:36I'd like to just say a few more things.

00:39I'm not a pharmacist.

00:41I'm a chemist, sir, that's right.

00:45I'm sorry I was disrupting you.

00:46Your Majesty,

00:48Sikandar has just had his British citizenship.

00:51He has been 13 years with us, so.

00:55So you're much more of a British citizen than I do.

00:57I'm a pharmacist.

01:01So, yeah.

01:04Eastern part, Calcutta.

01:07Yes, I see.

01:09It's a very interesting gateway.

01:13Yeah, so this is a multidisciplinary approach.

01:15There's not one particular area of science

01:17that's going to beat this by itself.

01:19So we involve chemists like Sikandar,

01:21John, pre-microbubble suspension.

01:24So this is a cross-section of the microbubble here.

01:27Okay, so it's like a sliced item.

01:29So this is a shell component here.

01:30And it's the same sort of molecules

01:32that are in the cell membrane of our cells in the body.

01:35Okay?

01:36And we can load the drug into the shell.

01:38Oh.

01:41So as I say, what's happening here

01:42is this one's been shaken.

01:44And ultimately, what we produce then

01:46is the suspension of all of the cells.

01:47You can see there's a big difference there between them.

01:50And so basically, what's happening is

01:52that these components are self-assembling around the...

01:56So I'm going to give you an opportunity to look at this.

01:58And I should probably say that we've prepared some before

02:01on the slide for you just to have a look at it

02:03if you'd like to.

02:04So just to see this.

02:05Because obviously, within this...

02:07Yeah, get up there, yeah.

02:08Okay?

02:09LAUGHTER

02:11Steve is good.

02:12It's already used in imaging and diagnostic ultrasonography.

02:17And so these bubbles have then been manipulated

02:20in this laboratory to host well-known chemotherapeutic drugs.

02:25And then also another mechanism called a free radical response.

02:29You can just even see the...

02:31The movement, yeah.

02:32The dots around the eye.

02:33Yeah.

02:34A shell.

02:35We're trying to find the Eureka moment

02:39in terms of cancer management.

02:41It's a different country.

02:43We do have one of our biggest affiliations

02:46which is the University of Oxford.

02:48Wow.

02:54Do you want to demonstrate?

02:55Sure.

02:59So what Ciarán and Thomas are going to show here,

03:02you might say, is that the bubble's actually bursting

03:04if they cancel the impulse.

03:06So that's just a polluted suspension of this, a slight pollution.

03:10So whenever he applies it to the ultrasound,

03:12you can see that this solution will come clear

03:14indicating that the bubble's burst.

03:18So if you could imagine, sir, that ultrasound is bonotumor.

03:22This research translates into much more therapeutic disease handling.

03:29You might want to say this is Professor Richie.

03:31Fantastic.

03:34That's great.

03:35That's actually my husband.

03:37Yes, it is.

03:39Yes, that's great.

03:40But I also have another company.

03:42That's Professor Mark Hebert.

03:45Cancer Management in the North West in Londonderry.

03:49Dr Thomas Adele is a Director of Policy

03:53working in the Department of Health.

03:55And then Miss Laura Mills is a Service Improvement Lead

03:59in the Northern Trust,

04:01again catering for Northern Ireland,

04:04but have all collectively spent many years

04:08in the pursuit of delivering the best.

04:11Mark has saved my life three times.

04:15So over the years we've built up a friendship.

04:20And I think that's very much part of the realisation

04:25of the value of patient input and contribution to research

04:29in our department.

04:31We've always had the only patient.

04:33I'm very happy to see much more of that.

04:37Just sitting on time.

04:42Not having read all of Mark's research papers,

04:46but helping to initiate research.

04:56No, you're not.

04:57We're just going for a commemoration of your visit.

04:59That was beautiful.

05:09Oh, and we have a small gift.

05:12Are we in one of these?

05:14We are.

05:16Appreciate that.

05:20We'll put it in that lab.

05:22Or at the entrance, perhaps.

05:24It's really the lab.

05:26Such an honour, sir, for you to be here.

05:28Thank you for all your work.

05:30I really appreciate it.

05:33We really do.

05:35And great to have it in the region here,

05:37and not all in Belfast.

05:39That's important to us as well.

05:41It's an important part of what we're trying to do.

05:43So we'll walk you out.

05:45We have lots of tea.

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