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  • 2 years ago
新闻报报看 | 中国上海的科研团队利用干细胞技术,成功进行了全球首宗自体再生胰岛移植手术,并成功治愈了一名患有25年糖尿病的患者。这名患者目前已经完全摆脱了对胰岛素依赖两年多,是再生医学治疗糖尿病领域的重大突破! (主播:庄文杰、林晓倩)

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00:00As we all know, diabetes is a permanent disease that cannot be cured.
00:06Once a patient is diagnosed with diabetes,
00:09in theory, he or she will not be able to reverse it for the rest of their lives.
00:13They will only be able to control their blood sugar for the rest of their lives and not get worse.
00:17Finger-picking to check blood sugar is a daily routine for diabetes patients.
00:21If the blood sugar is not under control for a long time,
00:24it may lead to insomnia, constipation, and other serious complications.
00:27When it comes to type 1 diabetes patients who lack insulin,
00:32and type 2 diabetes patients who cannot control their blood sugar even after taking oral medication,
00:37they need to inject insulin to control their blood sugar.
00:41Some people will be diagnosed with diabetes for the rest of their lives.
00:44But as medicine progresses,
00:46getting rid of diabetes is no longer an easy task.
00:50Last month, the medical team of Shanghai Changzheng Hospital
00:54published a study in the International Academy of Sciences.
00:59They claimed that they successfully cured a patient with type 2 diabetes for 25 years.
01:05At present, the patient has been off insulin for 33 months.
01:09This patient is a 59-year-old man.
01:12In 2017, he was diagnosed with terminal urinary incontinence and had kidney transplant.
01:19His kidney function was deteriorating,
01:21and he had to inject insulin many times a day.
01:24There was a high risk of severe complications.
01:27So, in 2021, the man decided to undergo a self-regenerating kidney transplant surgery.
01:32From the 11th week of the surgery,
01:35the man no longer needed external insulin.
01:38He gradually reduced the amount of oral blood sugar medication.
01:41Until the 56th week of his surgery,
01:45he did not need to take medicine at all.
01:47Subsequent examinations showed that the patient's guide function had returned to normal,
01:52and kidney function and other indicators were within the normal range.
01:56This shows that this treatment can prevent the progress of type 2 diabetes.
02:01This is really good news for patients with diabetes.
02:04How did the medical team do it?
02:07According to the report,
02:08Professor Yin, director of the organ transplant center of Shanghai Changzheng Hospital,
02:12said that their scientific team has been studying for more than 10 years
02:16to use PBMC, a single nucleus of external blood in the patient's bloodstream,
02:21to recombine it into a guide multi-function liver cell, iPSC,
02:26and use the world's first technology to transform iPSC into an intracranial liver cell,
02:33to create an extracorporeal guide organ,
02:36and then transplant it back into the patient's body to restore their guide function.
02:41This is a very complex research process.
02:45But the question is,
02:46does this treatment mean that in the future,
02:50all diabetes patients can use this self-regenerating guide transplant method
02:55to cure their diabetes?
02:58Director of the organ transplant center of Shanghai Changzheng Hospital,
03:01Dr. Ding Guoshan, said that
03:03the current research results are just preliminary research,
03:07and need to accumulate more cases and more in-depth clinical trials
03:11in order to provide a new treatment plan for diabetes patients who rely on guide transplant for a long time.
03:17In short, there is still a long way to go.
03:21But fortunately, now is a good start.
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