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00:07Millions of people worldwide are gradually losing their sight due to a rare genetic eye
00:12condition called retinitis pigmentosa. Retinitis pigmentosa is a group of inherited disorders that
00:18damage specialized retinal cells called rods and cones. In most cases, rod cells are affected first,
00:25causing difficulty seeing at night, followed by gradual damage to cone cells responsible for
00:31central vision. Over time, patients may experience night blindness, tunnel vision, light sensitivity,
00:39and progressive vision loss. Researchers are now exploring regenerative medicine to support
00:45retinal health and slow disease progression. Mesenchymal stem cells can release neurotrophic
00:50factors that may help protect existing retinal cells from further damage. Stem cells may also
00:56help regulate inflammation within the retinal environment. In RP, oxidative stress damages
01:03photoreceptors. Stem cells may release antioxidant-supporting molecules that help stabilize
01:09retinal cells. Rather than replacing cells directly, stem cells often work through paracrine signaling,
01:16releasing bioactive molecules that support nearby cells. Researchers are also studying
01:23transplantation of retinal pigment epithelial cells to support the layers essential for photoreceptor
01:28function. It is important to understand that regenerative therapies do not currently correct
01:35the genetic mutations causing retinitis pigmentosa. Early phase clinical studies focus mainly on safety.
01:42Some patients show temporary improvements, but long-term effectiveness is still under investigation.
01:49For patients with retinitis pigmentosa, regenerative medicine may offer supportive care,
01:55but careful medical evaluation and realistic expectations are essential.
02:00Stem Cell Care India helps patients review medical history, understand current research,
02:06and connect with ethically guided treatment centers.
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