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Scientists from the Centre for Molecular Cell Biology at Queen Mary University of London have discovered that caffeine stimulates AMPK, an ancient cellular energy system that plays a role in stress resistance, DNA repair, and growth—functions that are common to both yeast and humans. Their research, featured in Microbial Cell, indicates that caffeine influences AMPK indirectly, contradicting the previous understanding that it affected the TOR growth pathway directly. AMPK is also the target of metformin, a diabetes medication under investigation for its potential to promote a healthier lifespan, implying that caffeine could impact similar biological mechanisms related to aging healthily.
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00:00your morning coffee might be doing more for your cells than just waking you up.
00:04Researchers at Queen Mary University of London found that
00:07caffeine activates an ancient cellular energy system called AMPK,
00:12involved in stress resistance, DNA repair, and growth,
00:15a system shared across yeast in humans for more than 500 million years.
00:20Scientists expected caffeine to act directly on a growth regulator called TOR,
00:24but their new study, published in Microbial Cell,
00:28found it actually works indirectly.
00:30Flipping the AMPK switch first.
00:32That matters because AMPK is the exact same system targeted by metformin,
00:36a diabetes drug being studied for its potential to extend healthy human lifespan.
00:41Researchers say the discovery suggests caffeine could influence some of the same processes
00:46tied to healthier aging, opening doors to new strategies through diet, lifestyle, or future medicines.
00:53Disclosure. This video contains stock footage and content created or enhanced using AI-assisted tools.
00:58A lot of learnings can move respecto陌 broadly in the same way.
00:58Using AI-assisted algorithms,
00:58있습니다. This road voud Vidはありませんが、
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