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02:16to deliver drug treatments.
02:19Here in Yokohama, Professor Asako Yamayoshi is developing ways to deliver cancer drugs only to tumors, instead of attacking the
02:28whole body.
02:29Her research was inspired by a family member who died from cancer after severe treatment side effects.
02:35Her study uses exosomes, tiny bubbles that already travel through our body carrying messages between cells.
02:43She found a way to use these natural messengers.
02:58In simple terms, instead of creating artificial carriers, Yamayoshi's team simply attaches the medicine to these natural taxis, letting the
03:07body deliver the drug itself.
03:09This approach is unique, saving several days and speeding up the process.
03:14Most researchers first extract and purify exosomes in the lab.
03:19It's a complicated procedure. During this process, exosomes are often denatured.
03:28But in our system, we can use the exosomes inside of the patient directories so nucleic acid drugs can bind
03:38only to the target genes.
03:40That reduces side effects.
03:43Yamayoshi's system could make treatments faster and easier to scale, strengthening Japan's position in advanced biotech research.
03:53By working closely with clinicians, the team is refining the technology and understanding how it could make a real difference
04:01in the future.
04:02Professor Yamayoshi proposed a novel way of treatment and they directly treat peritoneal metastasis.
04:11Gastric cancer with peritoneal metastasis is a very severe disease condition and difficult to treat.
04:17The extreme target treatment reduces the cost of the investigation and the manufacturing.
04:23So it's very important, not only the patient and family, but also the health care system and the health care
04:30government.
04:32Yamayoshi's team is also testing light-controlled molecules to switch genes on and off with precision, another step towards gentler
04:41therapies.
04:43From accessible genetic data to targeted treatments, Japan's biotech scene is booming
04:48and pioneers like Takashi and Yamayoshi are leading the way.
04:52Thank you.
04:54Thank you.
04:55Thank you.
04:57Thank you.
04:59Thank you.
04:59We'll see you next night.
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