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Artificial intelligence just helped scientists uncover a hidden weakness in the monkeypox virus — a surface protein no one had targeted before. Using AlphaFold 3, researchers identified OPG153 as a powerful new vaccine target. When tested in mice, this single AI-selected protein triggered a strong immune response. This breakthrough could lead to safer, faster, and cheaper vaccines — not just for monkeypox, but even smallpox. Watch how AI is changing the future of disease protection.
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00:00AI just found monkeypox's secret weakness, and it could lead to a brand new, safer vaccine.
00:06In a breakthrough powered by artificial intelligence,
00:09scientists have uncovered a hidden protein on the monkeypox virus,
00:12one that no one had ever targeted before.
00:15Using AlphaFold3, researchers scanned dozens of viral proteins
00:19and zeroed in on a game-changing one called OPG153.
00:23Then they took it a step further.
00:25They injected this single protein into mice.
00:28The result? A strong immune response with powerful, neutralizing antibodies.
00:33Unlike current vaccines that rely on weakened viruses and are hard to produce,
00:38this new method is faster, safer, and much cheaper.
00:41Just one engineered protein could offer real protection.
00:45And because monkeypox is related to smallpox,
00:48this discovery might also help prepare us for future smallpox threats, including bioterrorism.
00:53Scientists call this approach reverse vaccinology.
00:56They started with survivors, found their strongest antibodies,
01:00and worked backwards to locate the exact viral target.
01:03Thanks to AI, what once took years, now takes weeks.
01:06This could be the start of a whole new era in vaccine design,
01:09one where AI leads the charge.
01:11And then, the first step up.
01:12If three, you can see it.
01:13And then, if the color is a mistake,
01:14you can see it.
01:15And then, first of all, you have the same.
01:16This could be the same.
01:17In the last step up.
01:18You have to create a fingerprint you can see it.
01:19And now you have to control the bullet and see it.
01:20That's the punch.
01:21Now, press the charge.
01:22And now I want to do it.
01:23It's time to break the damage.
01:24And now you have to back in the mirror.
01:25Here it's time to look.
01:26And now I want to hold it.
01:27And I want to hold it.
01:28Now, I want to hold it.
01:29And I want to hold it.
01:30And I want to get it.
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