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Portal CEO on Health Care's Expanding Funding Sources
Bloomberg
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2 days ago
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00:00
We've been talking all year long about GLP-1 obesity. We know that's a big market here,
00:04
but we kind of forget some of the progress that has been made in some of the other areas like
00:07
neurology and, of course, with exact sciences, a renewed focus by a lot of these companies on
00:12
oncology. Absolutely. I mean, oncology, you know, the beauty of some of the breakthroughs on the
00:17
therapeutic side is new modalities that are, you know, improving and extending lives in cancer
00:23
and previously untreatable tumor types. But as that happens, we've also learned that diagnostic
00:30
tools can predict and using those tools and finding cancer early can lead to better outcomes.
00:37
So if you look at what happened today with Abbott buying exact sciences from a commercial perspective,
00:42
obviously it expands the cancer franchise for Abbott. But at the same time, it's kind of a fun
00:47
story to think about when you go back to the origins of exact sciences. It's very much, you know,
00:52
that classic story of an innovator. You know, a lot of the early science came out of Johns Hopkins
00:56
University, Brett Vogelstein, and then a collaboration with Mayo Clinic, David Alquist,
01:04
and then Kevin Conroy came along, put the package together and really built an amazing company that
01:09
now is able to bring these diagnostic tools to patients since that's really the opportunity.
01:13
Well, with regards to those diagnostic tools, I mean, in the past when we talked about the biotech
01:17
industry, it was always about sort of that one killer, or actually the killer, but that one sort of big
01:21
drug that was going to be the treatment for whatever was ailing you. And we're seeing a much
01:25
more of a focus on preventative medicine, the idea of being able to diagnose and scan yourself
01:30
way earlier in that process. So you don't end up with the more extreme version of whatever disease
01:36
or ailment. And so much of that is a product of, you know, the genomics revolution, going back to the,
01:41
you know, early days of, you know, deciphering the human genome. And fast forward to today,
01:46
those discoveries and the ability to use those tools now at scale with supercomputing allows us
01:54
to be much more precise with understanding what is the genetic mutation in a cancer type or other
02:00
diseases, and how do we assign and prescribe the right drug to be able to be more effective? Because
02:05
drugs themselves always will have some untoward or, you know, off target effect, which leads to side
02:12
effects. So the more precise we can be with the capabilities of that drug by understanding the
02:17
diagnostic tools will be more effective at treating patients. Well, I'd love to tie this
02:20
conversation into what we're seeing in the political environment as well, because that's been one of the
02:25
hot topics this year is what does funding look like, particularly at the NIH level. So when you,
02:31
you know, think about all the smaller companies in this space, trying to develop these drugs,
02:36
what does the state of funding look like, not just from private investors, but from the government as well?
02:41
Well, there was a lot of noise early on. If you go back really almost a year to the day, you know,
02:46
RFK Jr., you know, was brought in place, you know, to be Secretary of Health and Human Services. So
02:51
the industry was somewhat concerned about that appointment. If you fast forward to today, you know,
02:58
Marty Macri, the head of the FDA, had a bold vision, and his bold vision was to accelerate drug
03:04
approvals, especially in rare diseases. And there's been some turmoil and turnover in the
03:11
ranks of the FDA. Really good news. You know, we've got Richard Pazder coming in as the head of
03:15
CDER. Right. But those things really, those fears have kind of waned off. As it turns out, NIH funding
03:21
has continued to remain steady. It's certainly cast a lot of concerns. Is that eagerness and innovation
03:26
there? Because, I mean, to your point earlier, I mean, we talk about, you know, the COVID pandemic and
03:31
Operation Warp Speed, which probably is one of the greatest, you know, achievements that we've had
03:36
as a country, certainly on the health care front. Yet you have an administration that almost seems
03:40
hostile to the same science that the previous administration sort of lauded. Yeah. I mean,
03:47
there's no question about it. We're living at a very confusing time when it comes to policy.
03:52
What we're trying to look at from an investor perspective is, and back to look at the markets
03:57
today, up 25 percent in the XBI index. And that came out of a deep hole. I mean, we've been in a
04:04
really a nuclear winter for the past several quarters. So what's driving that? What's driving
04:09
it is innovation. So these breakthroughs are leading to better treatments and better outcomes
04:12
for patients. We predicted and are now seeing more funding coming from alternative sources beyond
04:18
the government. Venture capitalists, but also like we have a company that's going after a Parkinson's
04:25
disease. It just was awarded a $5 million grant from the Michael J. Fox Foundation. States are
04:30
getting very aggressive and investing in innovation. So we're partnering with the state of New Jersey
04:34
around the New Jersey innovation hub. So Rutgers, Princeton, a lot of cool stuff happening there.
04:40
But in investing through the state instead of through the federal government is becoming more
04:45
prevalent. Texas, the Cancer Prevention Research Institute is a $6 billion fund that's investing into
04:53
companies. Three of our companies, Iterion, Crossbridge, and Novascan, were awarded $25 million. So
05:01
where the federal government may be pulling back or confusing people, other sources are popping up.
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