Trial Shows Ozempic-Like Medications May Help Manage Chronic Migraines

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00:00Trial shows Ozempic-like medications may help manage chronic migraines.

00:05Medications like Ozempic and Saxenda, GLP-1 receptor agonists,

00:10are popular for treating type 2 diabetes and aiding weight loss.

00:14Recent studies highlight their unexpected health benefits for the brain, heart, liver, and kidneys.

00:20They might also reduce migraines in overweight patients.

00:23Liraglutide, sold as Victoza and Saxenda, and semaglutide may be equally effective.

00:30The University of Naples study involved 31 high BMI participants with chronic migraines,

00:37showing that daily liraglutide injections reduced migraines from 19.8 to 10.7 days per month.

00:44Factors like sex and weight loss didn't affect results.

00:47Liraglutide may independently treat migraines.

00:50Larger studies are needed, but GLP-1 agonists could offer future migraine treatments.

00:55Migraines affect around 15% of the global population and often resist treatment,

01:03with individuals finding relief from medical options.

01:07Liraglutide provides relief by reducing intracranial pressure, mimicking glucagon-like peptide 1.

01:12Despite unmeasured mechanisms, it showed promise in animal models,

01:16supporting larger trials to evaluate GLP-1-R agonists for migraine management.

01:25Liraglutide offers multiple health benefits.

01:28It reduces heart attacks and high-risk diabetics,

01:31decreases cognitive decline by 18% in early Alzheimer's patients,

01:35and lessens alcohol intake from 11.3 to 4.3 drinks weekly.

01:40It also has neuroprotective and anti-inflammatory effects.

01:43These findings suggest broader therapeutic uses beyond migraine relief.