Modified Himalayan Fungus Compound Boosts its Anti-Cancer Properties 40x

Watch Modified Himalayan Fungus Compound Boosts its Anti-Cancer Properties 40x - Rizzle on Dailymotion

Transcript

00:00Modified Himalayan Fungus Compound boosts its anti-cancer properties 40 times.

00:05Oxford and Nucana developed NUC-7738, a chemotherapy drug from Cordycepin, enhancing anti-cancer

00:12effects by 40 times in 2021.

00:19Ophiocordyceps sinensis, or caterpillar fungus, from the Himalayas is vital in Chinese medicine,

00:25enhancing energy, immunity, and vitality.

00:29Cordycepin offers anti-cancer benefits, but its treatment efficacy is limited by rapid

00:33adenosine deaminase breakdown.

00:39Oxford and Nucana's protide-modified Cordycepin resists adenosine deaminase breakdown, enhances

00:45tumor concentration, and boosts efficacy.

00:48NUC-7738 increases potency by 40 times over unmodified Cordycepin in lab studies.

00:59NUC-7738 alters ribonucleic acid polyadenylation, induces cancer cell apoptosis, spares healthy

01:07tissues, and reduces side effects, enhancing patient experience significantly.

01:15NUC-7738 demonstrated strong potency in vitro and promising trials, used alone or with pembrolizumab

01:23for treatment-resistant advanced tumors.

01:26In a 12-patient study, 75% achieved disease control with NUC-7738 and pembrolizumab.

01:34One had 55% tumor reduction, showing promise.

01:40In 2025, Nucana aims to expand NUTIDE-701 study for PD-1 inhibitor-resistant melanoma and seek

01:48U.S. Food and Drug Administration regulatory approval.

01:53Researchers enhanced Cordycepin into NUC-7738, merging ancient and modern science, favoring innovative

02:00therapy methods.

02:01For more information, visit www.fema.gov.au.au.