00:00Now you can see where, yeah, follow the car. At some point the brakes will bind and then
00:06you'll have a problem.
00:08So basically she's doing a driving simulation, a racing game, and obviously going at high
00:12speed and at some point in the game, she doesn't know when, the brakes will start to bind.
00:16Now, in reality you have the smell of the burning of the brakes and you know to take
00:19your foot off the pedal. If you don't have the simulation in the gaming scenario, you
00:23won't and so of course you'll crash because your brakes will bind. So it's really giving
00:27a real world simulation which then tells you what's happening.
00:30Mind the wall.
00:35Gaming, of course, people want a more immersive gaming experience and of course smell is a
00:39very important part of the real world. So in the driving simulation that we're doing
00:42here, if you have the smell of the burning brakes, of course it's going to indicate there's
00:46a problem and you should maybe take your foot off the brake. So if you didn't have that
00:49smell of burning in the game, you wouldn't respond correctly.
00:51So basically we're mounting the smell device right above your nose. So when you puff the
00:55tiny bit of smell, parts per million, just in front of your nose and when you inhale
00:58you can actually get the smell, when you exhale you blow it out again. But it's only
01:01enough that you have the experience without puffing the whole thing into the environment.
01:04So it's really directed smell to your nose.
01:06Smell-O-Vision and scratch and sniff have been around for a long time but the big problem
01:09with any smell is if you puff smell into an environment, how do you get rid of it? That's
01:12the biggest challenge because then you're closing up, stinking up, the whole room stinks
01:15of it. So really the research element is trying to deliver just the right amount of smell
01:18that you have the immersive experience without completely smothering the whole environment
01:22in it. So how much do you need in order to be able to have the experience without suffocating
01:25the whole environment?
01:27It smells like a car crash, like burning tyres. It makes the experience quite different. It's
01:36a bit scary even. And difficult to concentrate because of the smell. Alarming.
01:46What we're doing, we're simulating all the senses. The real world is full of all senses.
01:50Visuals, audio, smell, feel and taste. So if you want to try and simulate the real world
01:54you need to include all of them. So what we're doing is simulating flavour, which is a combination
01:58of taste and smell. And we use it for, for example, a cooking game but more importantly
02:01we use it for healthcare applications to screen for Alzheimer's. The problem is you can get
02:05Alzheimer's in your 40s or 50s but you won't know about it until you're 60s or 70s when
02:08you fail a memory test. So how do we determine the people who've got it? Because before,
02:12November 2022, there was nothing you could do about it. But now there are new drugs,
02:15there's an advocate about which are available, which slow Alzheimer's down. But crucially
02:19only if it's caught early. So how do you determine who's got Alzheimer's in their 40s
02:22or 50s? They're not going to fail the memory test. So what you need to do is you need to
02:26MRI scan everyone every six months to check whether they've got it or not. That's not
02:29going to happen. So can we determine of all the millions of people who should be checked
02:32the ones that should be checked? And we can do that because if you have some form of Alzheimer's
02:36at the beginning you will affect your ability to taste and smell and so we can screen for
02:39that. We can check how good you are compared to your age or sex or ethnicity or compared
02:43to yourself six months ago. If you're not where you should be then you could have a
02:46problem and you should be looked at further.
02:49For more information visit www.ISGlobal.org
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