00:00Hi, my name is Dr. Meilan Han, and I'm a professor of pulmonary medicine at the University of
00:10Michigan in Ann Arbor, and I'm here today to talk about COPD.
00:14So, COPD is a progressive lung disease.
00:17It causes significant damage to the lungs, and it makes it really hard for patients to
00:21do normal things, like walk up the stairs or even get dressed in the morning.
00:26But I'm excited to be partnering with Sanofi and Regeneron to talk about a new treatment
00:32option that's now available for patients.
00:34It's called dupilumab, also goes by the name dupixan, and it treats a very specific type
00:40of inflammation in COPD that we can identify through a white blood cell called eosinophils.
00:46Patients who have high levels of eosinophils are at increased risk for these frequent exacerbations
00:51or flare-ups, where patients suddenly get more short of breath and need treatment with
00:56antibiotics or steroids.
00:59And dupixan, when added to a patient's normal inhaled medications, can really help to reduce
01:05the frequency of these flare-ups.
01:08Now, it's not a reliever medication.
01:11Patients still need to use their inhaled rescue medications.
01:14But over time, dupixan can really help to decrease the eosinophilic inflammation and
01:20reduce the frequency of these flare-ups.
01:22Now, as a physician, I'm excited to have a new treatment option available for patients.
01:28Patients have been asking me for years if there's something else on top of the standard
01:32medications I'm already giving them that could provide even more benefit.
01:37And unfortunately, I just haven't had a lot to offer patients until now.
01:41So I am really excited about this potential treatment option for patients with eosinophilic
01:47phenotype of COPD.
01:49Now, as with any medication, it's always about risk and benefit.
01:54So there's definitely more information on the website, dupixant.com, but things patients
02:00should know.
02:01Obviously, if you're allergic to dupixant, you shouldn't take it.
02:04Other side effects that have been reported include eye problems, joint aches, and muscle
02:10pain.
02:11The first place patients really should go is to talk to their doctor, ask them if they've
02:16ever had their eosinophil level checked, and whether dupixant might be right for them.
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