Physical and chemical properties of chloroamphenicol

Physical and chemical properties of chloroamphenicol

This antibiotic is slightly soluble in water (1 part of chloramphenicol per 400 parts of water), but it is highly soluble in alcohol, pyridine, ethylene glycol and propylene glycol.
Solutions cannot be sterilized in a steam sterilizer (autoclave) due to the weakening of the antibacterial effect.

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