King Charles refuses to marry Isabella (Carlos, rey emperador)

Charles V decides to marry Isabella of Portugal (Carlos, rey emperador)

Dowager Queen Mary of Hungary refuses to remarry (Carlos, rey emperador)

Charles V and Empress Isabella reconciliation (Carlos, rey emperador)

Charles V meets his bride Isabella of Portugal (Carlos, rey emperador)

Isabella of Portugal sends a letter to Charles V with Germaine of Foix (Carlos, rey emperador)

Charles V leaves Spain and Empress Isabella as regent (Carlos, rey emperador)

The Imperial Wedding - Charles V and Isabella of Portugal (Carlos, rey emperador)

Charles V and Empress Isabella reconcile (Carlos, rey emperador)

Empress Isabella helps Charles V in ruling (Carlos, rey emperador)

Charles V decides to make Empress Isabella regent (Carlos, rey emperador)

Isabella of Portugal learns that Charles V is engaged to another (Carlos, rey emperador)

King Charles sends his sister Eleanor to Portugal to marry the king (Carlos, rey emperador)

Empress Isabella learns she mustn't be pregnant again (Carlos, rey emperador)

Empress Isabella is Regent of Spain (Carlos, rey emperador)

Francisco de Borja confesses his feelings to Empress Isabella (Carlos, rey emperador)

Empress Isabella is pregnant (Carlos, rey emperador)

Isabella of Portugal arrives to Spain and meets Francisco de Borja (Carlos, rey emperador)

Isabella of Castile refuses to marry

Empress Isabella learns she is pregnant again (Carlos, rey emperador)

Empress Isabella helps Friar Bartolomé defend the Indians (Carlos, rey emperador)