00:00Welcome to 2-Minute Neuroscience, where I simplistically explain neuroscience topics in 2 minutes or less.
00:05In this installment, I will discuss the hypothalamus and pituitary gland.
00:08The hypothalamus is a small region situated directly above the brainstem.
00:12It is made up of a collection of nuclei with a variety of functions,
00:15but in general, the hypothalamus is involved in controlling the two H's, homeostasis and hormones.
00:21Homeostasis is a term used to describe the maintenance of balance or stability in a biological system.
00:25The hypothalamus can maintain homeostasis either by exerting direct influence over the autonomic nervous system
00:31or by causing the release of hormones.
00:33The hypothalamus manipulates hormone release primarily by controlling the pituitary gland.
00:38The pituitary gland is a hormone-secreting gland that sits just below the hypothalamus.
00:42It is sometimes called the master gland because it not only secretes many extremely important hormones,
00:47but it also regulates the activity of other hormone-secreting glands throughout the body.
00:51The pituitary gland consists of two lobes, called the anterior and the posterior pituitary.
00:57The anterior pituitary is responsible for the release of a number of hormones
01:00that have widespread effects throughout the body.
01:03They include growth hormone, which is involved with growth,
01:06follicle-stimulating hormone, which plays a role in development and reproduction,
01:11luteinizing hormone, which is essential to testosterone production and reproduction,
01:16adrenocorticotropic hormone, which is involved with the stress and fear responses,
01:19thyroid-stimulating hormone, which is important to healthy metabolism,
01:23and prolactin, which promotes milk production in females.
01:26The release of these hormones is controlled by the hypothalamus,
01:28which sends signals in the form of releasing hormones
01:30to tell the anterior pituitary when to secrete its hormones.
01:34The posterior pituitary also secretes two hormones, but does not synthesize them.
01:38Instead, they are synthesized by the hypothalamus
01:40and then sent to the posterior pituitary for release into the bloodstream.
01:44The names of these hormones are oxytocin and vasopressin.
01:47Oxytocin has important roles in facilitating childbirth and lactation,
01:51but is also thought to have a role in compassion and social bonding.
01:54Vasopressin's main functions are to control urine output and regulate blood pressure.