00:00Millions of people are taking Ozempic, Wegevy, Munjaro, and ZepBound.
00:04And now, researchers say there may be side effects that clinical trials never fully captured.
00:09A team at the University of Pennsylvania used artificial intelligence to scan
00:14more than 400,000 Reddit posts from nearly 70,000 self-reported users of these GLP-1 drugs.
00:21As expected, well-known effects like nausea and fatigue topped the list.
00:25But two categories stood out as genuinely surprising.
00:29Changes in menstrual cycles and temperature-related issues like chills and hot flashes.
00:34Neither of which shows up clearly on current drug labels.
00:37Researchers say the method is picking up a real signal.
00:40Since it also caught obvious symptoms, doctors already know about.
00:44Study authors are careful to note this doesn't prove the medications actually caused these reactions.
00:49Since Reddit users aren't a representative sample of everyone taking these drugs.
00:53But they say patterns this consistent.
00:56Coming straight from patients without any prompting.
00:58Are exactly the kind of early warning signs that clinicians should be paying closer attention to going forward.
01:04Disclosure.
01:05This video contains stock footage and content created or enhanced using AI-assisted tools.
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