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00:00Scientists warn of parasite that can enter the body and increase cancer risk.
00:05Schistosomiasis is caught in fresh water when larvae slip into skin unnoticed.
00:10S. mansoni can block nerve alerts and may raise liver and colorectal cancer risk, studies suggest.
00:19In mice, Schistosoma mansoni dampen TRPV1-positive sensory neurons that signal pain,
00:25itch, and burn, reducing heat sensitivity. Activating them beforehand triggered an early
00:30immune response. Researchers found these nerves act as a defense against infection.
00:35World Health Organization notes S. hematobium is a group 1 carcinogen linked to higher bladder
00:41cancer risk. Liver flukes O. vivarini and C. sinensis cause bile duct cancer, while S. mansoni
00:48may raise bowel and liver cancer risk through chronic inflammation.
00:56Schistosomes need snails and humans to survive. Snails release larvae that penetrate skin in seconds,
01:02putting 250 million people at risk in Africa, Asia, the Middle East, and the Americas.
01:08Tourists can also get infected, but oceans and chlorinated pools are safe.
01:12Europe is rarely affected, although outbreaks such as the 2013 Corsica outbreak
01:17show that transmission can occur. Check safe swim areas when traveling,
01:21use treated water for bathing, and see a clinician if exposed.
01:28Dr. Dabrowski R. Herbert noted that studying how the parasite blocks TRPV1-plus
01:34could lead to new pain treatments and therapies for painful inflammatory diseases.
01:39In high-risk areas, avoid contaminated water and get tested if exposed. Use chlorinated or boiled water
01:45for bathing. Effective treatments can help prevent inflammation and related complications associated
01:50with cancer.
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