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  • 10 months ago
In this episode of "The Future You," Dr. Nir Barzilai outlines the12 hallmarks of aging as interconnected targets, why fixing even one can trigger improvements across the entire system.

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00:00We know that we can target the process of aging, delay it significantly, even stop and reverse it in some context.
00:09And we've done it in animals, and we've done it in humans.
00:14Now to your question, you know, what is this biology?
00:18And I'll tell you really simply, we geroscientists agree on a concept that's called the hallmarks of aging.
00:26What are the hallmarks of aging?
00:28Something that goes wrong when you're old, and when you fix it, you can fix it in animal with genetic ways, or with drugs, or in humans also.
00:39You target this hallmark, you reverse the aging, you extend the health span of the animals and humans, and you increase their lifespan.
00:50That's how you become a hallmark.
00:52Now, there may be 12 hallmarks like that, but the important thing is, you fix one, you can fix the others.
01:00Most of the drugs that we're doing are doing that.
01:04So you don't have to fix all of them at one time to get an effect.
01:09Maybe it's going to be better if you do that.
01:11But we have a biology, we have targets, and we can start dealing with it right now.
01:18We have targets, because we're not going to be able to fix all of them.
01:31We don't have to suffice it.
01:32We don't have to be fascinated by the biology of the animals.
01:36But we don't have to be able to fix all of them.
01:39You don't have to be able to fix them in this way.
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