🧬 Don't Die: The Man Who Wants to Live Forever (2025) 💀 | English Audio | Netflix Documentary 🎥 | Full HD Movie | Watch Now on Dailymotion 🔥

Name: 🧬 Don't Die: The Man Who Wants to Live Forever (2025) 💀 | English Audio | Netflix Documentary 🎥 | Full HD Movie | Watch Now on Dailymotion 🔥
Uploaded: 2025-05-30T11:31:46+00:00
Duration: 1 h 29 min 51 s
Channel: KatFlix

KatFlix

🧬 Don't Die: The Man Who Wants to Live Forever (2025) 💀 | English Audio | Netflix Documentary 🎥 | Full HD Movie | Watch Now on Dailymotion 🔥
Are you ready to witness one man’s journey to cheat death? Don't Die: The Man Who Wants to Live Forever (2025) is a gripping and mind-bending documentary now streaming on Netflix, and this is the English Audio HD version exclusively on Dailymotion! 🎬🧠

🎞️ Documentary Summary:
In this revolutionary documentary, tech entrepreneur Bryan Johnson—best known for creating Braintree and Kernel—embarks on an intense experiment called Project Blueprint to reverse aging and achieve human longevity.

With the help of doctors, nutritionists, and cutting-edge biotechnology, Bryan follows an extremely disciplined routine including:
Strict sleep schedules 😴
Vegan diet 🌱
Over 100 daily pills 💊
Red light therapy 💡
Blood plasma transfusion from his teenage son
This film, directed by Chris Smith (Fyre, Tiger King), is both captivating and controversial. It explores whether immortality is just a dream—or the next step in human evolution. 🧬

📽️ Key Details:
🎬 Directed by: Chris Smith
👤 Starring: Bryan Johnson, Talmage Johnson
📺 Streaming On: Netflix
📢 Audio Language: English
📆 Release Year: 2025
🕒 Runtime: 1h 33min
🎞️ Genre: Documentary, Sci-Fi, Futuristic Health

🔔 Subscribe Now & Stay Updated!
📺 YouTube Channel: https://www.youtube.com/@CineVerseOfficial-X
🎥 Dailymotion Channel: https://dailymotion.com/cineversestudio
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00:00:00Talent is the ability to hit a target no one else can.

00:00:21Genius can hit a target no one else can see.

00:00:24And if we say in the early 21st century,

00:00:27what is the genius target for us, for our time and place?

00:00:32And I would put forward that it's the ability to stop our self-destructive behaviors

00:00:37and neutralize aging.

00:00:44You must have heard of the curious case of Benjamin Button,

00:00:47a story where a man ages in reverse.

00:00:50One man wants to achieve that feat.

00:00:53His name is Brian Johnson.

00:00:55Brian Johnson is determined to live forever or die trying

00:00:59and is putting his vast fortune and own body on the line to achieve it.

00:01:04As a species, we accept our inevitable decay, decline and death.

00:01:11I want to argue that the opposite should be true.

00:01:15I walked into this because I was marching into an early grave.

00:01:22And now I've built an algorithm that takes better care of me than I can myself.

00:01:27I think this is the first time in the history of the human race

00:01:32that it is not known how long and how well I can live.

00:01:40Three, two, one, action.

00:01:42This is the man spending millions to become 18 years old once again.

00:01:46Brian Johnson.

00:01:47My name is Brian Johnson.

00:01:49I've been spending millions of dollars creating an anti-aging protocol.

00:01:52Two dozen supplements and medicines, exercise an hour a day,

00:01:55plus high intensity three times a week.

00:01:57This 45-year-old millionaire has reversed his age by five years.

00:02:01His doctors claim he has the heart of a 37-year-old,

00:02:04using his life as a science experiment to see just how long he can live.

00:02:09AKA Project Blueprint.

00:02:11Hi, everyone.

00:02:12The past three years we've been trying to master the basics, sleep, diet, exercise.

00:02:16Today we're doing the first next level therapy, gene therapy.

00:02:20Oh, shut up, Brian.

00:02:22Fucking Brian.

00:02:23Anything taken to an extreme can potentially be harmful to the body.

00:02:27I don't think I particularly want 33,000 images of my bowels.

00:02:30You've got to have a bit of fun in your life. Where do you find the fun?

00:02:32When do you go raging?

00:02:33Do we really believe that he went from being old to young?

00:02:37I don't.

00:02:38If I had $400 million, I wouldn't be doing what you're doing.

00:02:41This is not an accessible method of reversing the effects of aging.

00:02:45This guy's in his own fucking world.

00:02:47It's not really reality.

00:02:49If you look at all the discussions about me,

00:02:52many times people will say,

00:02:54this is a rich person trying to live forever.

00:02:56Is it going to be so awesome when they get hit by a bus?

00:02:58Lol.

00:02:59Because these are really hard ideas to get your head around.

00:03:02And so to me, the only relevant thought experiment that each of us can do

00:03:06is do we want to live tomorrow?

00:03:09Most of us are going to say yes.

00:03:12If we feel healthy and well, there's always something to do tomorrow.

00:03:17And so I want people to embrace that day to day until eventually we say,

00:03:23don't die.

00:03:24Don't die.

00:03:54Don't-

00:04:00This is the gym and it's my happy place.

00:04:01Every morning I come in here and I exercise for roughly an hour.

00:04:05I do about it 35 exercise circuit.

00:04:09Everything we do, we measure it.

00:04:13able to see in a closed loop way is it working or is it not what are you finding so i had a

00:04:19whole body mri recently and i'm in the 99th percentile for optimal for both muscle and fat

00:04:27across my entire body have you ever been this in shape before no never in my life

00:04:35it feels good

00:04:36hey ollie

00:04:45ollie we'll do the blood draw real quick

00:04:50dr oliver zolman and i were connected by a friend oliver had spent his entire adult life scouring

00:04:57the literature on anti-aging science when brian first reached out he seemed a bit lost

00:05:04whatever he was doing didn't really seem like it was working optimally for him so i showed him my

00:05:13longevity level one two three protocol level one is doing the basic stuff diet exercise and then each

00:05:20layer you go up it gets more sophisticated his approach was in order to understand human aging

00:05:27you needed to look at the organ level because the heart is going to age differently than the lungs

00:05:32and the lungs differently than the kidney previously i would use my mind to decide what

00:05:37to eat so at the grocery store walking down the aisles and looking at this thing and that thing and

00:05:42put it in the cart zolman flipped that on its head and said what if i asked my organs to speak for

00:05:48themselves what if the heart and the liver and the lungs could actually speak what they need

00:05:53and then my responsibility is to do exactly what the body tells me to do

00:05:57blueprint is brian doing this level one two three protocol to the most that it's ever been done

00:06:04he's been the best guinea pig anyone can ask for

00:06:09it's probably over a hundred different things i do any given day that the body has asked for to be

00:06:16in its ideal state and that begins with in the morning i wake up i turn a specific light on in my

00:06:21bathroom that gives me sun-like exposure i take three pills i do my body temperature with an inner

00:06:27ear measurement go downstairs start hrv therapy so i put a little electrode here in my ear and it

00:06:34stimulates my autonomic nervous system trying to make my body more parasynthetic and more chill

00:06:40i take 54 pills with a concoction that i call the green giant

00:06:45treatment i put a cap on my head for hair growth it has 312 laser diodes then i work out for an hour

00:06:52come in eat a few pounds of vegetables i do some high frequency electromagnetic stimulation on my abdomen

00:06:58i do 12 minutes of near and red light therapy to accelerate healing i do audio therapy for my hearing

00:07:05regeneration i have my last meals to eat before 11 a.m 34 more pills to take there's protocols throughout the

00:07:13day here and there and then my nighttime routine by doing blueprint one of the key objectives is to

00:07:21achieve the lowest possible biological age so just like a tree has rings we all have a signature inside

00:07:29of our body of our age after doing blueprint now for two years i've reversed my biological age 5.1 years

00:07:38i have 50 perfect biomarkers i have 100 biomarkers where i'm less than my chronological age

00:07:45and my speed of aging is 0.69 which means for every 12 months i age eight months

00:07:54in terms of how far this goes it's open-ended we have no idea but i want to take my speed of aging

00:08:02to the lowest possible number step back a little bit yeah and a little bit closer to the bed

00:08:17yeah great and then you can just like literally rattle everything off okay so today is a very exciting

00:08:25day for me because for the very first time ever after tracking my sleep for four years i achieved my

00:08:31first perfect month so i have an average of 100 sleep performance for 30 days i go to bed at 8 30 pm

00:08:41i've averaged 8 hours and 34 minutes of sleep every night the body loves routine so go to bed at the

00:08:47exact same time every night no excuses sleep is not something that can be dismissed so hopefully these tips

00:08:53help you that you can start inching towards uh better sleep it will change everything in your life

00:09:00wonderful okay good okay what's your role on this i don't even know how to describe it

00:09:08take it take a stab um i just am i am here on the mission trying to make whatever needs to happen

00:09:17happen happen in order to get there that's my role kate has been with me from the very beginning

00:09:23of blueprint yeah how do you feel are you converted to be honest when i first started i was eating

00:09:29mcdonald's um philosophically converted when i first met brian it was not healthy and we started talking

00:09:40about the philosophy of blueprint and all of a sudden i was like okay when i laugh about not being

00:09:47fit and not being able to exercise and that kind of stuff i'm kind of laughing in the face of my future

00:09:53self like i don't want to be that person you know when i'm 60 and i'm unable to run around or yeah

00:09:59can i get you turning off so it was a huge wake-up call for me now here i am like the other person

00:10:07behind this mission i mean like you could be fed up by saying like every morning i do the same four

00:10:14hour routine and this is what starts it off that's good when we first started working together brian

00:10:20asked me to develop the communication side of things his big ambition was to get blueprint out to the

00:10:27people so that we can all learn from what blueprint is up to but it was like hitting our head against

00:10:34the wall for a little while because it was just a bit of an empty void on the internet and then one

00:10:40day i had this idea what if we publish all of his biometric data online and made it a thing that

00:10:49people could witness and watch the protocols the measurements the recipes the supplements we

00:10:54published all on my website and this journalist i knew actually events saw this and expressed

00:10:59interest in doing a profile on blueprint brian put all of his stuff online i was like all right this

00:11:05guy's somewhere between off and like very interesting i went to visit him at his house with his own home

00:11:13laboratory and we just kind of like started talking when doctors visit our clinic here they get pretty

00:11:20excited because we have outfitted this so that we can be a medical grade uh operation at every every

00:11:27level and i started just asking him questions he's like okay i spent 2.5 million dollars on all this

00:11:33stuff and this was not a professional athlete who was spending this much money on his body it was just

00:11:38this random tech guy it's just you know absolutely going further than what anyone else had done and so

00:11:44that's when i really knew this actually was the story i remember the day before the article came

00:11:50out kate and i were in my office and we both had this moment of crisis like oh no like what have we done

00:12:03one man he spent two million dollars to effectively reboot his body millionaire entrepreneur brian johnson brian

00:12:10johnson johnson brian johnson is on a quest to live longer all of a sudden every spotlight was turned

00:12:17on brian and the project and everything we worked on was under intense scrutiny i think his rectum went

00:12:24viral his rectal biological age there was so much online video people were making and it's just kind of

00:12:32a blur we were inundated with interest every single product that we published on the blipper website

00:12:39was sold out within days nobody could get anything that we used we couldn't either we

00:12:44uh we had suppliers calling us saying what is going on it also unlocked a colossal amount of hate

00:12:51i actually would say he doesn't look that healthy there's something super weird about looking young

00:12:55forever like he takes like 40 vitamins in the morning and 40 more in the afternoon that seems tedious

00:13:02i know it's like i'd rather just die sooner and the irony of this specifically is you're seeking more

00:13:08time when you're not even living the time you've been given yes yeah and i find this so vapid

00:13:16i think for most people the longevity field has always been looked at skeptically it's just

00:13:22these rich silica valley types chasing the fountain of youth jeff bezos threw more money behind

00:13:28an obsession to become among the billionaires on a quest to defeat aging space internet and now live

00:13:38forever geez it's like seen as strange and fringe it just so happens it is a real field of science

00:13:48there are proper doctors and scientists that look at this we're all so used to watching our friends and

00:13:56relatives and pets age and die we think it's somehow natural and therefore somehow good but i describe

00:14:01aging as our greatest humanitarian challenge aging causes cancer aging causes heart disease aging causes

00:14:08dementia aging causes stroke it makes us more susceptible to infections it makes us more frail

00:14:13and actually if you look at causes of death across the world today the leading killers are these diseases

00:14:18like cancer and dementia and heart disease i think the real promise of this field is that

00:14:24we have the opportunity by targeting the biology of aging to delay or prevent many maybe all of the

00:14:30functional declines of diseases that go along with old age and that's huge we're still i would say at an

00:14:37early stage but there's already been a number of breakthroughs there's already a number of

00:14:41interventions including drugs and diets that in animal models slow down the process of aging we have

00:14:49robust evidence that we can extend the lifespan of a mouse so if you're a mouse we've got you covered

00:14:55but what that also means is that we have a lot of things to test in humans

00:15:04we are experimenting and we are trialing out and i think we will have a revolution in the next coming

00:15:1110 years of very specific interventions we can apply to humans to then lower the biological age

00:15:19you could get within four millimeters that's a lot better i know that's really great i'm benefiting

00:15:25from decades of progress that people have made in the world of anti-aging science and the scientific

00:15:32interventions are moving forward very fast and so it has a tangible sense of it's here and i want

00:15:39people to know about it i think light them up okay i think a little more yeah i think i just need a

00:15:50little bit of an angle with your whole legs and everything if you can yeah so let me do another test

00:15:59wow that's so striking yeah hopefully it captures a new zeitgeist that we're after

00:16:04here yeah i think um everything looks good i'll just go to different heights

00:16:11chin up a little bit yeah my poor son he comes home and he never knows what's going to be happening

00:16:18here that's great you ready yeah i'm ready

00:16:24how's brian as a dad he's a pretty good dad yeah when his mother and i split he was with her for the

00:16:38past couple years and then he decided to move across the country and live with me for his senior year

00:16:45oh good job tom was found to stride he's been smoking me what's your take on blueprint when the

00:16:52article came out everyone's like oh isn't that your dad so i got like so many texts from friends and

00:16:57people at school asking me all about it worth it did people think it was cool or did they think you

00:17:03guys were weirdos both yeah even though i've been at my school for months now people are still asking

00:17:10me questions every day about it oh no you played so well that was a good rally that was good i've

00:17:19been around brian since before talmadge was here and i remember thinking like how is brian gonna get

00:17:24used to having talmadge around like another human being in his space every single day because he's such

00:17:28a private introverted individual um but now it's like he's completely restructured his life around

00:17:35talmadge being here today is an exciting day because how many schools did you apply to

00:17:4415. how many schools have rendered their decisions 12 not including today yeah so these are so this is

00:17:52the last then now you're gonna have all the information you need to make a decision

00:17:57on what college you're gonna go to and you're gonna leave me in five months

00:18:05yes i only have 150 days left with talmadge which makes me incredibly sad

00:18:19there is just never enough time hey welcome nice to meet you thank you so much for opening your

00:18:25house and showing us everything next challenge yep let's go you're vegan yeah i'm vegan by choice

00:18:31talmadge and i eat the exact same thing every day every day and then i've been working on the splits

00:18:35so we'll go do the splits as we eat breakfast okay i think if you really want to live the brian johnson

00:18:41lifestyle the commitment to that is obscene i do 2 000 calories a day are you ever hungry

00:18:47i'm pretty hungry okay the saddest part of my day is the last bite your entire day revolves around this

00:18:55quite solitary very rigid kind of lifestyle wait wait brian brian brian you can't see sunlight

00:19:02did you go in the sun the uv index is well below dangerous levels so we're good to go

00:19:07it seems sort of like depressing and like what kind of life are you leading if you're just giving

00:19:12yourself up to this you know it's interesting because obviously you have like this extra level

00:19:19of discipline but we know for instance about cigarettes that people who smoke a lot like if

00:19:25they smoke three packs a day on average you'll live 11 years less than people who don't smoke so so what

00:19:31you're saying is almost like an advanced version like if i cut out smoking i'll live 11 years more

00:19:36than average if i cut out drinking i'll live five years more than average and on and on and yet people

00:19:41know this about smoking and they still smoke yeah i mean you're exactly right our minds which

00:19:48we think are our primary tool of problem solving is actually the source of our self-destructive

00:19:56behaviors so i would argue the mind is dead what the sorry the mind is dead and the goal is to give

00:20:05complete control of your well-being over to an algorithm you know who says stuff like that

00:20:09algorithms the first reaction most people have is panic it's like well my free will is the only

00:20:15reason i exist and if i can't eat what i want to eat then i have no reason to exist yeah it tastes like

00:20:20nutrition that's just a knee-jerk reaction it's just the mind panicking because it feels like its

00:20:26authorities in question ready ready the conscious mind is desperate to hold on to power the catch is we

00:20:36can't trust our minds because the way we've structured society right now is insane every day we eat

00:20:43millions of burgers pizzas and french fries now scientists say we may not only be feeding ourselves

00:20:50we may be feeding an addiction we expect people on their way to work to pass 20 fast food places

00:20:5820 places selling sugary drinks we ask them to navigate the addictiveness of social media the world's

00:21:04most powerful algorithms trying to get them to spend every waking second on the algorithm

00:21:09navigate alcohol and the smoking and binge watching and porn and every other form of addiction

00:21:15and then we look at the individual and say why aren't we happier

00:21:18we have lost touch with basic self-care we're inebriated we can't see straight even though we know

00:21:30that eating the wrong kinds of foods or drinking or smoking or not practicing sleep accelerates aging

00:21:35disability even death we can't stop we're in a fight for our lives with ourselves

00:21:48i have found more relief in demoting my mind and elevating my body that i have in my entire life

00:22:03it feels so liberating to me because my entire life i was desperate to be free from myself

00:22:18from when he was young brian was a problem solver

00:22:25when he was in junior high he knew that we didn't have very much money and so there's times like when

00:22:32brian would not eat lunch and contribute his lunch money he was always coming up with something to help

00:22:38the family i remember at some point brian took a job at a sandwich shop but that was short-lived brian said

00:22:47that he would never work for anybody ever again you know that kind of i'm gonna do it by myself

00:22:54now brian you you're a lifelong entrepreneur i am what do you think you learn more from the success

00:22:59or the failures i never dwelled on failure it didn't discourage me it was in the beginning

00:23:04my entrepreneurial adventures had little to zero success i had a baby i couldn't pay the bills and so

00:23:12i took the only job i could find which was selling credit card processing door to door this experience

00:23:18got me interested in the world of payments so i started poking around and i saw that paypal was

00:23:23the dominant payment provider that had grown up during the internet but then once ebay had acquired them

00:23:28the development had discontinued so i started braintree with the idea of building modern software he had

00:23:35this little tiny office he was working on a card table please look at that no please do that i don't

00:23:42know when he got a desk i didn't take any outside capital we were one of the fastest growing companies

00:23:47in america twice we acquired venmo in year five and we became part of the global payments infrastructure

00:23:54all right everybody let's give it up for brian johnson

00:23:58it was so exciting so i don't think that i realized that there was also that other side that

00:24:07was haunting him i couldn't believe how much effort people put into building the company it was amazing

00:24:13staying there all night multiple nights in a row when i was building brain tree venmo

00:24:18i was just grinding myself into the grave it was a social norm that an entrepreneur would go days

00:24:25without sleeping and if you told that story people would be in awe and there would be mythology about

00:24:29you like amazing that they did this now i view this as totally foolish i would wake up the next day

00:24:36ornery not feeling restored and then having to muster up the strength to walk in and be like all right

00:24:41everybody we're gonna work hard and we're gonna solve all these burning problems that are going on

00:24:46i was stressed out of my mind i'm turning this off coming home at night and dealing with three kids

00:25:00i'd be exhausted and unpleasant after a guaranteed fight with a partner i would turn to unhealthy food

00:25:08as my soothing mechanism pure sugar and of course that just made things worse because my sleep would

00:25:14then suffer and it would just compound upon itself i was miserable i remember one particular visit

00:25:23he didn't say too much but at the end i could tell that he it was a really difficult time for him

00:25:33and when he left i cried

00:25:34had you ever seen him that way and i didn't know till then

00:25:49sundays were my hardest days because i would go to church and everything about being there made me

00:25:57dissolve growing up in the mormon church my entire family was there my entire community was there

00:26:05and it gave me all the answers to existence it had stories about what existed before this life

00:26:11why we are here on this earth what's afterlife but with the intensity of what life was delivering up

00:26:18i felt like those answers the only reality i knew didn't make sense anymore i was kind of just dropped into

00:26:26this nothingness i remember discussions with him where he was having real problems with the religion

00:26:35not just like some kind of philosophical dispute these were things that were so integrated into him

00:26:43he was having physical symptoms i would come home from church i would lay on my bed my son at the

00:26:50time he was seven years old he would sense something was wrong and he came up and he would rub my back

00:26:56and i was not able to even move

00:27:01and the only thought that would soothe me was the idea of doing a deal with the devil

00:27:07and ceasing to exist i didn't want an afterlife i didn't want this life i didn't want consciousness at all

00:27:29what changed my mind was like a vicious storm telling me to literally kill myself

00:27:36and it became clear to me that the mind is not a reliable source of judgment

00:27:42i needed a different way of being

00:27:48it took me several years to rebuild myself in that time i sold my company braintree vanmo

00:27:54i got a divorce i left my born into religion and ultimately i found strength and liberation in doing blueprint

00:28:02my heart when i give my body authority it doesn't commit this self-destructive harm

00:28:11my heart doesn't deliver these stinging insults my lungs don't do it either my kidney doesn't either

00:28:17removing my mind has been the best thing i've ever done in my life

00:28:21but leaving the church fractured my life with my family

00:28:30when brian decided to leave the church it was very heartbreaking for me

00:28:34and i i had to go through a process of thinking about the person he is and thinking about what he's doing with his life

00:28:47to find peace family is a fundamental teaching of mormonism and when my dad left the religion

00:28:57it felt like it was violating that teaching and that we couldn't be

00:29:00a family anymore so i definitely as a eight-year-old i viewed him as losing his path

00:29:14the church camp last summer before i came out here and we had these

00:29:34booklets to take notes in and while everyone else was taking notes about you know feeling the spirit

00:29:41like feeling like feeling good the community scripture i was taking notes about trying to

00:29:49decipher everything i felt like i was in this system and i was trying to take it apart

00:29:57prior to moving to california i was in mormonism but ever since i was young it had never really been my

00:30:04thing and no one in there saw me or saw the situation i was in i couldn't talk to anyone

00:30:11over the years me and my siblings would visit my dad periodically and i started to let my dad in a

00:30:18bit talmage started inquiring me of certain things like what about this and what about that

00:30:23and we established this rapport with each other where we were able to have these honest dialogues

00:30:28he just saw me so clearly he knew the situation i was in

00:30:32it was wild because when i would talk he would then articulate what i was thinking

00:30:36and i slowly came to the realization that i wanted to get out of the religion in any way possible

00:30:44after multiple attempts i eventually managed to come out here and spend my last year of high

00:30:50school with him i know a lot of my friends or people in general feel like their parents

00:30:56misunderstand them and it takes some experience to unify them so it kind of makes sense with us

00:31:05took leaving the church and now with that shared experience we can connect on so many deeper levels

00:31:13yeah me and my dad we have the best thing going on but no one agreed with it

00:31:23like i can't think of a single person who's like you know what tom what you should do that

00:31:26that'll be good for you it was like coming to live with satan

00:31:30all right you do this let's do it i increased my weight on my curls i noticed

00:31:45how's my hip on this dad let's see

00:31:50you can i'm impressed you can do that after that many

00:31:53wow that's art

00:32:02i wish i had talmadge's legs

00:32:06he's kind of the perfect specimen

00:32:11but you've heard that brian wants to become talmadge

00:32:15yeah so yeah it's important not to over-rejuvenate because there could be side effects have you told

00:32:22that to brian oh yeah we discussed this at length

00:32:28up until this point we've been doing things people are familiar with diet and exercise and sleep

00:32:33and it's almost like okay what's the next level we looked at every health span and lifespan study

00:32:42that's ever been done whether it be on humans or mice and then rank them according to their efficacy

00:32:48their ability to extend life and now we're trying to figure out how to do them we started

00:32:56human growth hormone and then so you stab this in the leg and then you press it some of these

00:33:02therapies can be very dangerous and then it's a little teeny needle you see that but we are on the

00:33:09side of you know extreme caution we're doing high frequency measurements across the whole body

00:33:15so if we do start seeing side effects we pick them up fast and try some other therapy

00:33:21how many pills did you take a day today today i'll be 130

00:33:27what's yours 26. we know that it's unrealistic for a normal person to do this wildly rigorous routine

00:33:36but i think what brian is trying to do as the first prototype for blueprint is do the absolute extreme

00:33:45thing i absolutely acknowledge that not everyone has the time and the resources and the life

00:33:51circumstances they can do it i'm trying to be on the absolute outermost edge of possibility for the

00:33:58science i'm trying to show what's possible it's pretty safe so far and maybe it'll work and maybe

00:34:06we can learn something from it and then take that out and everyone else can benefit sooner rather than

00:34:11later today is rapamycin day so rapamycin is a drug that people use to suppress the immune system when

00:34:23they're getting an organ transplant so you get a new organ in the body you don't want the immune system to

00:34:28reject it and so you take rapamycin and it suppresses the immune system i take this because there's

00:34:34potentially some longevity benefits it's the kind of thing in the longevity community that people are

00:34:39excited about outside the longevity community it's still kind of crazy like you know if you're like

00:34:43yeah i take a an immune suppressing drug that's wacky like why would you ever do that

00:34:51rapamycin was a drug that was first discovered in soil bacteria that were isolated on easter island

00:34:57what happened in 2009 was that a really rigorous study in mice found that it can extend lifespan

00:35:03and it didn't just keep them alive for longer it kept them healthier for longer as well

00:35:07and this has been demonstrated in study after study in loads of different conditions in loads of

00:35:10different labs the only thing we're lacking is human data

00:35:15honestly i think rapamycin is probably still the most robust candidate for something that would affect human

00:35:21longevity but they have to be used with caution because you can have bad things happen when you

00:35:25take too much one two three four five six seven eight nine ten eleven twelve thirteen thirteen because it

00:35:30suppresses the immune system role side effects can include very dangerous bacterial infections things

00:35:36like pneumonia or cellulitis or pharyngitis to avoid negative effects we took a dosage and measured the

00:35:44levels of my blood two hours after taking the dose 24 48 72 96 you can start seeing if you get two high

00:35:51levels or two low levels then adjust the dose based on that you know with this precise formulation as far

00:35:57as far as we know we are on the most aggressive rapamycin protocol of anyone in the industry

00:36:06do you follow brian johnson at all i've met him before what's your take on what he's doing

00:36:18some of the interventions that he takes like rapamycin they work in mice we don't know if they

00:36:24would work in humans we need to have properly designed experiments then we could make scientific

00:36:30conclusions but what brian's doing it's not a scientific approach this is the supplement uh warehouse

00:36:38he's taking hundreds of different interventions and that means it's very very hard to identify which

00:36:43if any of them are working what you really need to do is a clinical trial where you get thousands

00:36:49of people not just one and you give them all the same intervention at the same dose

00:36:54i think there's value in these individual n of one experiments where people are testing different

00:37:00things on themselves but it's never going to be accepted by the broader medical community or

00:37:06regulatory um agencies we need the more rigorous clinical trials brian blocked me on twitter because

00:37:14i suggested that he use some of his hundreds of millions of pounds to fund a clinical trial

00:37:18specifically the tame trial which wants to find out metformin is actually an anti-aging drug brian

00:37:24takes metformin so if he wants to know if what he's doing is actually of any use to him then it'll be

00:37:28of huge value to him and the rest of the longevity community to fund this trial but i'd guess he didn't

00:37:33like me telling him how to spend his money whoa that's really good what brian does i guess brings attention

00:37:42to our field this will be positive but it has almost no contribution to science right it's not

00:37:49science it's just attention so yeah we're going to be filming some shorts we've been playing around

00:37:54with doing that so we're upping our social media game yeah we had our first victories the past two

00:38:01weeks we had two of our videos get a few million views three just on instagram and one on tick tock is

00:38:08approaching i get messages all the time hey can i get connected with your pr firm well you're talking

00:38:14to it like there's two of us come on fry guy i appreciate this let's go is that all you got

00:38:21i think you're just kidding youtube sent us a box presented to brian johnson for passing 100 000 subscribers

00:38:30a lot of people are clearly very interested in anti-aging we're all aging we all probably like

00:38:37to know how to slow it down at least a little bit brian johnson if you look at the media that he's doing

00:38:42himself he's clearly intending to reach as many people as possible the real question is what's his

00:38:48motivation today i'm going to show you about this device i use to do the equivalent of 20 000 sit-ups in 30

00:38:56minutes we sound like an infomercial i know i'm going to say like something's wrong here

00:39:03if you buy right now the button low-right 19.99 four easy installments free shipping

00:39:09brian johnson is going to die one day furthermore it is my personal opinion that brian johnson is a grifter

00:39:16who regardless of whether or not he actually believes he's going to live forever is absolutely

00:39:22trying to make a quick buck off of people who are terrified of the idea of death and who

00:39:29have more money than common sense okay i got something special today what is this this is

00:39:38the very first blueprint product we have brian johnson's blueprints ultra premium extra virgin olive oil

00:39:47this is the oldest trick in the book as far as self-help scams and just plain old marketing go you

00:39:53convince people of the problem and then sell them the solution i've seen one take one a roll get me on

00:40:02your anti-aging routine and do it fast but make it simple that's the most common thing i hear how's that

00:40:09i think that blueprint is a commercial enterprise if you go onto his website every single link on that

00:40:15blueprint page is an amazon affiliate link which means that if you click on it and buy something

00:40:18on amazon he gets a small cut of the money so this whole thing i think has been optimized as a

00:40:22money-making venture i mean obviously he's very rich he's a very talented businessman so that's going

00:40:26to be the way that he looks at things sounds like olive oil i would say very similar to most olive oils

00:40:32a lot of the hate that we get a blueprint is kind of interesting in that i make products available

00:40:36for people to also become healthy and make the life changes they want to do and people hate on me

00:40:41like he's like i see some people on twitter giving a really hard time for all the merchandise

00:40:48i've followed him for years and and i'm 100 convinced this was not like the master plan

00:40:57i remember he was trying to do blueprint for a couple years and it was this very personal quest

00:41:03that's a lot of volume seven of these today he turned to this hardcore health regimen as the solution

00:41:09to these mental health problems yeah i think he believes in what he's doing it's a huge difference

00:41:15i imagine this is like emotional for you in a sense that like it sounds like you want completely happy

00:41:20with your past self no um i feel like that person's gone

00:41:34you should probably get better lighting though i have an idea

00:41:47oh i think that looks good cool idea the morning rituals that talmud and i have together it's a big

00:41:54part of our lives you say what do you think but soon talmud will be doing this in his dorm in chicago

00:42:01i will be here by myself how do you feel about that challenge talmud is not looking at this from a

00:42:07fear of loss talmud is looking at this from a opportunity of gain and particularly a girlfriend potentially

00:42:13can i take my pills yes

00:42:27because i remember when i was going to college as well loss of anything in my family environment was not

00:42:33even on my radar it was entirely about all the new life experiences yeah i'm excited i do view it as an

00:42:41opportunity for gain but there is loss too yeah

00:42:50going through this experience i guess it invites me to have a lot more empathy for my parents and

00:42:54what they may be going through like my dad if you think about him and age he said the other day

00:43:00he googled what happens when you turn 70 or when you're over 70 and he said jokingly don't do it

00:43:06like every morning you wake up and it's like how am i doing is there one more thing that's broken or

00:43:13that hurts more like i wonder what that must feel like

00:43:17i've always been a mental guy i've always thought that i could honestly think about 10 things at the same time

00:43:36but i got to the point where i would write a paragraph that didn't make sense

00:43:41that scares me to death one day my father called panicking he said i would do anything

00:43:50to continue with my mental acuity and i said dad i'm doing this plasma therapy for myself there are

00:43:58other people who are doing it for alzheimer's parkinson's and i said you know if you're interested

00:44:02you can come to texas with me and like i would love to give you a liter of plasma there it is there's

00:44:09the plasma there are certain interventions that truly reverse the ages for example this idea of

00:44:18young blood plasma the reversal effect can be observed in this study where researchers connect a

00:44:26young mouse to an old mouse they literally connect their arteries and veins so there's a blood exchange

00:44:37and you can see that young plasma circulated through the old mouse reverses the epigenetic ages of

00:44:45multiple organs in one study we saw a reverse of 50 percent in a rat then in another study more recently

00:44:53in mice 30 percent when we're looking at plasma i guess option one you'll sew me together with a

00:45:01with a young human that's not practical we we said we can't do that one so the next case is we look

00:45:06at these plasma exchanges i didn't see the vision at first but brian told me that this would be someone

00:45:13doing something for their loved one that mattered it was actually an investment in their health by giving

00:45:20them some of your health and so i tell talmage like hey like grandpa's pumped about this so we start

00:45:26talking and like we said what if you did it too you donate your plasma to me i will to dad it'll be

00:45:34this multi-generational thing what do you think and he instantaneously said yes i'm in we're 34 000

00:45:41feet we're flying to dallas we just had some food the talmage is right behind me

00:45:50i need to check in to see what he's eating to make sure his plasma is okay

00:45:54the plasma stuff always sounds super creepy to anyone who hears about it for the first time

00:46:00but brian was not the first guy to do this years ago there would be these stories about peter thiel the

00:46:06venture capitalist one of the first investors in facebook draining the blood of some young healthy

00:46:11people i'm not sure that that's true but but this all got out into the wild it sort of got parodied

00:46:18in the show silicon valley everything okay uh is price your assistant no of course not it's my

00:46:23transfusion associate most silicon valley people if they had a blood boy they didn't want anybody to

00:46:29know about it but brian being brian kind of embraced all this and was out there parading his blood boys

00:46:37around on twitter and taking photographs you guys look awesome it did have the elements of like absurdity

00:46:44that i thought would come with brian having the whole family show up as if you were going to like a ball

00:46:50game except you were just all gonna swap plasma oh what the plasma bus got decorated love

00:46:59flows from the heart i guess it's really the vein but but this is amazing

00:47:07hey look at that that's pretty plasma wait so what's good about this the color's really nice it's

00:47:14pristine i'm actually honestly scared that it's going to be more clear than mine like it'll be

00:47:19embarrassing it's like i'm hoping you know it's good but i'm also yeah i understand that it's

00:47:25competition i understand that i mean this is the way you can tell am i a fraud or not right like

00:47:30absolutely all right haters yeah what'd you say about this i have identified the world's first vampire

00:47:39anti-aging fanatic who spends more than two million dollars per year to retain youth uses teen

00:47:45son as quote blood boy bruh his son needs to watch out right now his son needs to run oh the ditty mail's

00:47:53up yeah okay some of the comments on the ditty mail what a weirdo disgusting and satanic what a waste of

00:48:00time oh humanity's so great

00:48:03the plasma transfer blew up on social media and of course the easy place to go is is vampire blood draw

00:48:16blood boy and the mean spiritist instead of drawing my my ire and my absolute anger really made me sad

00:48:26all right dad let's get you a new pillow one thing people don't get this was an event that transcended

00:48:36the trial of a therapy you know how special this is you know the the connection and everything this

00:48:42is just like a manifestation of all that commitment everything else yeah better than words better than

00:48:49words when you become invested in the other person to the point that you step up and you share biology

00:48:59having that kind of intimacy with both brian and with talmage for me it was a chance to reconcile

00:49:10when i was early married you would never see a more serious mfr in mormonism than me

00:49:16but the problem was it was not my life when i was younger my father went through some difficult times

00:49:24with professional challenges and drugs his mom and i separated and got a divorce

00:49:31at that time i wasn't sure whether to find a girlfriend or have a line of coke to go to temple

00:49:37or go have a scotch when your life is so

00:49:41so screwed up to that point you and you have no idea what your moral standards are it all falls apart

00:49:49it was like a 95 percent likelihood that he would fall through on anything like pick me up from school

00:49:59you know help me with a homework assignment like call me when he said he would like it just it would

00:50:02never happen that probably affected brian the most of any of the kids he was the one that wanted to go

00:50:10with his dad he's the one that waited for him i think it hurt him a lot

00:50:18he got arrested when i was 22 and i went and saw him in jail and that was a moment for him

00:50:29guess who came to see his dad

00:50:30and words of judgment like god dad clean up your act no you can do it dad

00:50:42did anyone else come no

00:50:43me being at that point and being at this point i mean have brian uh holding on to me having talmage

00:51:08what could be a better statement of reconciliation love you dad yeah love you

00:51:18what a great experience you feel the love

00:51:22it was one of the most precious life experiences we've ever had

00:51:26it morphed into this multi-generational healing bonding experience and was less about the therapeutic benefit

00:51:43i feel like a parent and a child that maybe takes different paths can find a place for a good

00:51:51relationship but it has to be a joint effort for both

00:52:01why are you having that reaction it's hard work sometimes and it's not without its heartache

00:52:09but it can be done

00:52:10having this time with my father i reflected a lot on being a dad

00:52:21all right here we go okay guys hi mister hey talmage it's been one of the most painful experiences of

00:52:29my life where two of my children keep me at bay because i'm not part of their religious organization

00:52:36so i feel like i missed out on meaningful part of their lives

00:52:40and it's been the most special experience in my life where one of my children has fully embraced me

00:52:47i wish my other children would join me

00:52:49how much last night i did a a phone call date with somebody i met on a dating app

00:53:17we're gonna go out on a date next week i wish her the best of luck you wish her the best of luck yeah

00:53:29relationships are really important and you know with talmage leaving

00:53:33i guess i need to rebuild my life i told her it might be a bad idea she seemed undeterred

00:53:41normally when i engage with somebody and we're contemplating being friends i make a list and i

00:53:49say here are the 10 reasons why i'm a bad idea you know i have this protocol that is rigorous i'm

00:53:57impossibly hard to be with and ultimately you're just gonna hate me and so i try to get in front of it

00:54:03and oftentimes people will laugh i'm like no for real this is really what's gonna happen i don't know

00:54:09maybe it's a really bad strategy brian deserves to have companionship in his life and i think he's

00:54:19always struggled to find that i feel like there's a conflict within brian between family brian the one

00:54:26that wants a partner wants to just like hang out you know be around loved ones and then the ambitious

00:54:33brian who says like every ounce of my energy needs to be dedicated toward this mission

00:54:48i went on two dates with this one woman and

00:54:54we we got along fairly well but i think she basically was like

00:54:58you're so far outside the norms i just don't know if i you know like if i can make sense of this whole

00:55:04thing are you willing to change no

00:55:12let's just say relationships have never been my strength i was married at the age of 24 i didn't

00:55:19have any girlfriends before that so then when i got divorced 13 years later i had no idea how to deal

00:55:25with partnership brian is a complicated person and i remember we had a conversation with some

00:55:33concerns am i ever going to find someone that were really fit with me realizing that he was quite

00:55:38unique i guess i just kind of stumbled through social attractions and my first girlfriend after

00:55:46getting a divorce has ended up in a pretty ugly lawsuit ah that's a cool headline tech mogul brian

00:55:53johnson who spends two million a year for 18 year old body cheated and dumped fiancee after she got

00:55:57breast cancer lawsuit what how's that a lawsuit though johnson had agreed to provide lifelong financial

00:56:04support oh this is where the lawsuit comes in then she got um breast cancer she came she

00:56:12and she became a net negative and a bad deal for him he described her as a business oh my god

00:56:22brian's relationship with taryn i think was a very sweet relationship for both of them

00:56:29i saw how happy it made them and so it was surprising to me to hear some allegations

00:56:35taryn filed a lawsuit against brian taryn claimed after the cancer treatment brian demanded that she

00:56:43move out of the residence they shared he told her that he would be willing to assist her with rent and

00:56:48expenses but only if she signed the separation agreement almost like hey sign this nda and i'll

00:56:54give you the money she had no independent source of steady income she tried to resist but brian was

00:56:59manipulative being labeled as this awful person for all these things i was rattled deeply we dated for

00:57:08a couple years and when we separated she hired one of the most powerful law firms in the world

00:57:14they sent me this letter demanding that i pay them nine million dollars that week or they were going to

00:57:21make these scandalous statements about me i felt like they were all false allegations and so i said

00:57:27i'm not doing it okay game face what is game face if someone were to put a game face on we were in

00:57:35arbitration where everything's confidential but then the media found the lawsuit in the california courts

00:57:41and then published all of her allegations

00:57:46facing the destruction of my personal reputation by my former girlfriend and fiance it's hard for me

00:57:54to walk into a relationship and trust that there's not some alternative motive a lot of people of

00:58:00course say like boohoo you're a rich person problems or whatever okay uh sure also it stinks because it

00:58:09does create a significant barrier for meaningful relationships because it just it complicates everything

00:58:14but with talmage our relationship is rich and dynamic game on

00:58:26that was amazing where's talmage i gotta find talmage there he is yes did you see time what is it i beat you

00:58:36oh no we can run it back tomorrow i've never had a relationship in my life that has been this

00:58:45consistent and steady and soothing and fun it has all the characteristics of everything i've always wanted

00:58:55in a best friend yes you're killing it and so i i think yeah there's a meaningful amount of

00:59:01influence that talmage has on this project talmage ryan johnson

00:59:09people think i'm fearful of death i'm not i love life and i love living life with talmage

00:59:19do you worry about him or you think he'll be good on his own i do worry about him like yeah we're

00:59:26gonna really miss each other happy birthday talmage yeah previous generations you have kids so that

00:59:32you can pass the torch and now you have kids so that you can journey with them i mean don't die is

00:59:39real like i want to journey with talmage for some indefinite period of time

00:59:43i'm serious about this i really do want to have multiple lifetimes with talmage and go through all

00:59:53the different phases a hundred years is not gonna be enough

00:59:57you're ready yeah whenever you're ready okay hi everyone today is one of the most exciting days of

01:00:09blueprint we're going to travel to an island just off the coast of honduras and i'm going to be

01:00:14injected with my first gene therapy if you look at the age charts of humanity humans have a 120 year

01:00:21ceiling so if we want to say we're going to punch through this limitation of human lifespan

01:00:26is going to be through gene therapy under our socks shorts shirts gene therapy is considered

01:00:32you know taking it as far as you can at this point so it's kind of the extreme measure of treating

01:00:39biological aging the state of gene therapy at the moment is that we're using it in the clinic but

01:00:44we're using it for very serious conditions conditions where we know that there is a single gene that's

01:00:49causing the problem and we can say editing this gene in this way would be successful the idea of using

01:00:54gene therapy for aging is hugely exciting but today the science just isn't ready and in fact there's

01:01:01quite a big risk because there are these things called off-target effects and so this is where the

01:01:05gene therapy goes in and it modifies not just the dna that you're trying to modify but it modifies some

01:01:09other part of your genome many interventions do rejuvenate cells but that incurs a risk that the cells

01:01:18then turn into different cells malignant cells cancer cells gene therapy is dangerous and we have been

01:01:27evaluating various gene therapies for the past almost two years now this is the only one that had the

01:01:35potential lifespan extenders that we were looking for that also met our safety criteria

01:01:41in what brian's trying to do in his journey is there any part of you that's nervous for what he's trying to

01:01:45achieve yes yes i am nervous where brian's going because me i'm i'm logical and smart when i get to

01:01:55the end edge of the the the ledge i stop i'm never i'm never taking the next step into the abyss

01:02:07generally a person would get a gene therapy in a clinical trial and the problem with clinical trials

01:02:13is they are limited certainly there isn't gene therapy for aging in clinical trials at this moment

01:02:21so other than that you would travel for medical tourism and one place that gene therapy is being

01:02:28offered is roatan honduras there is a free zone there called prospera

01:02:35prospera is a special economic zone that the state of honduras has licensed with the ability

01:02:42to create new business laws that are favorable to innovations like our gene therapy here we're able

01:02:51to operate under a ethics review board and a committee that makes sure that we're doing everything up to

01:02:57standard all this that you see is prospera i'm gonna look out for dinosaurs we're working on an axe

01:03:04you know we are planning on doing trials in the united states however it's a thing it takes some

01:03:12time and it's not necessarily time devoted towards laboratory work it's more of a thing of legal issues

01:03:20and having lawyers communicate on your behalf with a very large and very bureaucratic regulatory agency

01:03:27that's what we're doing it's going to be working it's go time all right this way if i'm being honest

01:03:33prosper is like a batshit crazy idea it's like you just take over a little bit of land set up all your

01:03:40own rules i like mac and walter very much they seem like nice guys they didn't strike me as as you know

01:03:4820-year phd type scientist and so it was like the first thing brian's done where i really was like is this

01:03:57a good idea if there's anything you have any questions about whatever information you need we

01:04:04will do our best to provide any kind of diagnostic anything we will do our best i appreciate that walter

01:04:14when me and max started the company we wanted to make a big difference in people's lives

01:04:18you know we're dealt a certain hand at our birth we're dealt with the genes we're we're given and we

01:04:25want to give people options this gene therapy which is folistatin has primarily been used in body

01:04:34building where you're looking at increased muscle mass and strength for some people bulking up is

01:04:40desirable but generally with age sarcopenia osteoporosis and frailty are severe problems our gene therapy

01:04:49treats that either preventatively in young people or in a reactive way in older people who are already

01:04:54experiencing it if you look at the mouse lifespan studies where it was used they had a 30 percent

01:05:00lifespan extension and so if i end up looking like a marvel character all the better can i get some help

01:05:07on this after the gene therapy i'm not gonna fit in this thing or maybe i'm gonna you know i'm gonna hulk out

01:05:14of it he's so confident but i'm a little worried for him like we just don't know how his body's gonna

01:05:22react and i would just i would hate for anything to happen to him it's really important to note any gene

01:05:32therapy that integrates into your existing genome does change your dna our gene therapy does not

01:05:39integrate once you get injected it's not editing your dna it's just giving you an added piece of dna

01:05:45that's parallel and creates a little export factory with folistatin most gene therapies because they

01:05:52integrate into your chromosomal dna once it's there it's there and you can't turn it off our gene

01:05:59therapy doesn't integrate and so we've introduced the concept of a kill switch it's potentially safer

01:06:05because if you want to turn it off there's a few methods that we could use to make it reversible

01:06:10hey are you ready for this i'm ready for this all right let's go

01:06:22here it comes

01:06:25this thing's just a little bit

01:06:35geez i wish we could drag this out but that's it

01:06:38thanks doc clean and injections very good i am now officially a genetically enhanced human

01:06:50when people see someone like me doing gene therapy

01:06:54many think of inequality or they see a divide between rich and poor

01:06:59the way i think about it is if we can prove that this gene therapy is safe and effective

01:07:04and then you know ten thousand people are willing to do it that price is going to go down doctor

01:07:11thanks yeah really appreciate you they're very expensive interventions like gene therapy that we need

01:07:18to test for academics it's prohibitively expensive to do the human clinical studies and maybe longevity

01:07:26clinics where people pay a lot of money or places we can at least get some data so i'm not against having

01:07:32clinics available but once we find out how things work we have to figure out how to scale them and

01:07:38make them broadly available i don't know if we'll live forever but at least we absolutely will buy the

01:07:44next guy some more time and you know i'd rather give my children more years than i had the opportunity

01:07:51before so thank you so much for believing in us yeah thank you both of you that's right yeah

01:07:58wow that looks still enough to walk on if we if we put a camera on top i can walk on water here

01:08:07from homo sapien to homo deus testing out whether the gene therapy if the effects have taken

01:08:13be careful jacob don't die no one can die brian when he was young really lived from religion

01:08:30you know i can remember a stage that he went through where i mean he literally wanted to be

01:08:36like joseph smith joseph smith of course is the founding prophet in mormonism and i think the thing

01:08:43that you see is a continuing principle with brian he wants his life to be such that he would stick out

01:08:51like a joseph smith his reward will be when he affects change change to him is the aphrodisiac it is

01:09:01it is the drug health and wellness is all like religion with the bible it's not hard to make the argument

01:09:06that he gave up on the church had to find a new religion and has turned health and himself into

01:09:12this religion and it's this very narcissistic enterprise 15 000 views in three hours 585 comments

01:09:21receiving attention having people care about what he's doing i think he does care about that but i

01:09:27don't actually think it like undermines what he's doing because it's so out there in the open

01:09:32i made a statement yesterday that jesus has had 2000 years i don't see any evidence of his work

01:09:40i've done more in two years how'd that go as you might expect he talks about himself as being kind

01:09:49of health jesus with like a little bit of humor but also i think quite a bit of pride hi guys hey he's

01:09:56embracing the culty aspect of this all and it only seems to be building more and more momentum

01:10:03how do you think i appear to your friends it's like the only way for me to understand that is if

01:10:08one of my friends dads was starting a cult and how i'd look at that and i probably wouldn't think much

01:10:17of it because you're doing it am i starting a cult yes am i yeah it's not a bad thing it just is

01:10:27i know brian's tried to force this to be a religion there's a part of me though that thinks this is

01:10:32almost like the right religion for this moment in some ways it is like this antidote to the way the

01:10:39world thinks about health there are still serious concerns about the nation's health care system the

01:10:45national health service is broken why is the system letting doctors and patients down the approach

01:10:52to health in pretty much every developed nation has really been centered around waiting until people

01:10:59develop a disease and then attempting to cure that disease but in reality pretty much just treating

01:11:04symptoms one of the consequences of that is that the prevalence of chronic disease has increased

01:11:10dramatically over the last 50 years we think you know i'll go to bed at 90 and i'll die in my sleep

01:11:16that almost never happens if you go into a geriatric ward and you see people incontinent immobile if we

01:11:23do look at it if we stare this in the face it's particularly unpleasant at the moment we are spending so

01:11:29much money treating very sick individuals i think we have to ask why wouldn't you invest earlier in life

01:11:36to keep them healthy to not having so many people with age related diseases you know in the u.s doctors

01:11:44are generally paid on procedures and i remember when i was at the buck doing research on aging there was a

01:11:51large hospital chain that was thinking about giving a donation to the research and we talked about

01:11:56healthspan and the ceo looked at me and said well if we do this you're going to cut our procedure rate by

01:12:0360 percent why would i do this and so we need to think about how we really want to focus on the

01:12:08health of the population i think that's the most like admirable part about what brian is doing it's

01:12:17the most proactive thing you can imagine and if the medical system was wired even just like a little

01:12:23bit more this way i think it'd probably be good for the rest of us if we can solve this fundamental

01:12:30problem we may walk into a future where all of us live healthier and longer with the people that we care

01:12:38about three days that's so wild to me i know it's here think of it i've been acting all tough guy like

01:12:54yeah i'm going off to college oh but when i start to think about it like i'm defeated oh

01:13:00shit i'll get over it i just i just feel defeated it's like it's like you're you got me but now you're

01:13:07losing me again yeah yeah yeah

01:13:221921 it's a close game dad i was down then you were down yeah you came back but come back good job

01:13:28job you too good game i've always been the talmage whisperer from the moment he came out of the womb

01:13:37i was the one who could quiet him i settled him and it was just my little talmage and this week he's

01:13:44ready to go hi mister do you need help with anything today no

01:13:50my priorities involve stuff i do by myself with kids help

01:14:03he's learned everything he needs to learn from me and i was just going through the typical parental

01:14:10process of having you know someone leave your nest yeah i like it cute yeah

01:14:20okay

01:14:26talmage brian johnson ready to go as soon as i step past this i'm out the voyage begins

01:14:38welcome talmage thank you

01:14:50Talmadge, happy college prep day.

01:14:58Do we have a starting plan?

01:14:59Are we going to kitchen stuff first?

01:15:02Are we following you around?

01:15:03Are we engaged in the process?

01:15:05Do you know what you're going to do?

01:15:07You get linens over here.

01:15:09Linens and a comforter.

01:15:11What's your bed size?

01:15:13So complicated.

01:15:15Over here, Talmadge.

01:15:19You got me?

01:15:20Yeah.

01:15:25Oh, God.

01:15:26I confess, I just about started crying

01:15:28when we walked by that place, all the little toys.

01:15:31Yeah, I saw you.

01:15:31Yeah, I lost my breath.

01:15:34Kind of goes against your whole emotionless thing.

01:15:37Yeah.

01:15:37Why am I crying in Target?

01:15:52So much going on inside of me, I don't even know.

01:16:09Mm-hmm.

01:16:14Okay.

01:16:16Like a blue?

01:16:20Gray?

01:16:21Green?

01:16:22I think I'm a green kind of guy.

01:16:23These past 150 days, Talmadge has been this presence in my life.

01:16:32We just love each other.

01:16:33And if we look at all the science about humans, the humans thrive in community.

01:16:38They thrive in positive relationships.

01:16:46Yeah, it's not a good thing to be alone.

01:16:48So I wouldn't be so brazen to think that I'm going to defy

01:16:53what the science shows on human connection and community.

01:16:59Do you have a plan?

01:17:00No.

01:17:10Welcome to the University of Chicago.

01:17:21Do you see it?

01:17:22Right there.

01:17:26This is perfect.

01:17:27Everybody had a fan.

01:17:28That's nice.

01:17:28These are nicer than I have.

01:17:31Do you have a preference on which side you want to expose to your skin?

01:17:35See, this is front, face, left.

01:17:39I feel like it's really going to hit once you say goodbye to me when I'm in my door.

01:17:44I've never felt more understood by anyone than with you.

01:17:50So yeah, I hope you don't die.

01:17:55I don't know.

01:17:56I just keep reflecting on all the things that have happened this year.

01:18:01All the life lessons.

01:18:03Yeah, it's going to be hard to rival this.

01:18:08Thank you, too.

01:18:09All right, Talmadge.

01:18:15Brian Johnson.

01:18:19Second version of you.

01:18:23Let's get after it.

01:18:24Yep.

01:18:25Let's get after it.

01:18:26Let's get after it.

01:18:27Let's get after it.

01:18:28Let's get after it.

01:18:29Let's get after it.

01:18:30Let's get after it.

01:18:31Let's get after it.

01:18:32Let's get after it.

01:18:33Let's get after it.

01:18:34Let's get after it.

01:18:35Let's get after it.

01:18:36Let's get after it.

01:18:37Let's get after it.

01:18:38Let's get after it.

01:18:39Let's get after it.

01:18:40Let's get after it.

01:18:41Oh, my God.

01:19:11The house is awfully quiet. I guess now it's real. It never felt real. And now it's quiet. Just still. I wonder how he's feeling.

01:19:41Can I show you the solution? Yes.

01:19:55You want to look at my screen? So, let's say you're just, like, on the Blue Room website. You're just looking at food. There's this.

01:20:04How are you feeling today?

01:20:05You know, in many ways, I don't think I really could have gone to the next stage until I got things settled with Talmadge.

01:20:11I really needed him to be in a good place at school or on his next stage of life. And I think he's there. So, I feel emboldened to take my next step, too.

01:20:20Ready? Let's do this.

01:20:25Hey, what's up, friends? Today is Don't Die Hike number four. It was less than two months ago that I messaged out on social media, hey, I'm going on a hike. Join me. And I had 11 people. Today, there's over 400 people.

01:20:42Oh, my goodness. There's a lot of cars. Wow. Wait. And there's more people than this is. What? This is crazy.

01:20:51Hi, everyone. Hey, guys. Good morning. Hey. You look 10 years younger than last time.

01:20:57Big group hug in the morning.

01:20:58Come on. Come on. Come on.

01:21:03Over time, I guess I've gone through different stages of my feelings about Brian.

01:21:11And at the very beginning, his lifestyles struck me as quite solitary.

01:21:16But as more people have bought into this, he actually seems to be creating these friendships I never expected.

01:21:23Okay, everyone. Let's go up this way.

01:21:25Woo! Woo!

01:21:27For Brian, I can tell there's a lot of enjoyment from this.

01:21:31And so, I think he's kind of flipped the narrative.

01:21:34You made it. Good job, everyone.

01:21:35Woo!

01:21:36I'll confess, this is a cult.

01:21:38It's a sick and twisted cult to get you to go to bed on time.

01:21:46There's little bits and pieces of that that are unnerving.

01:21:49But I think I see him now almost as like a philosopher.

01:21:52I mean, he's sort of trying to prove a point.

01:21:54Okay, cool.

01:21:55It's this, like, don't die thing, which I really thought was sort of a joke as I saw this evolving.

01:22:02But there is some merit to it, I think.

01:22:04Whether you believe in Brian or what he's doing or not, it's an interesting question to ask if society has just taken a wrong turn.

01:22:13I think it drives some people crazy and it inspires others.

01:22:16What's up, guys? I'm Talmadge.

01:22:19I'm Charles.

01:22:19I'm Kylie.

01:22:20And we're hosting the Don't Die event in Chicago.

01:22:23Don't die in Chicago!

01:22:25Don't die from Cologne!

01:22:27Don't die in Dublin!

01:22:29Don't die from Santa Fe!

01:22:30In Barcelona!

01:22:31In Hong Kong!

01:22:32Don't die!

01:22:34What we're talking about is really a medical revolution.

01:22:38If there's an opportunity to stay healthy and stay functional and stay your grandkids, would you rather have that or would you rather wait until you get Alzheimer's and take some drug that slows the progression down by 30%?

01:22:52Aging is not inevitable.

01:22:53At least it can be delayed.

01:22:55And you can do that right now, probably by changing your lifestyle.

01:22:59Lifestyle factors are obvious, but it's important.

01:23:02From sleep quality, dietary modifications, regular exercise, and social interactions, we can get 10 years, 15 years of extra quality life.

01:23:14And that number will probably get bigger with time as we develop more effective interventions.

01:23:18You can see right there that fluid is mesenchymal stem cells.

01:23:23We haven't obviously yet got any human treatments that I'm happy to recommend.

01:23:26But I think because I know that these treatments are being developed, and I think they're potentially going to be available within our lifetimes, I'm much more excited by following basic health advice.

01:23:35Because it means I'll hopefully be alive and healthy long enough to benefit from these first treatments.

01:23:40And what's even more exciting is that then if I benefit from those first treatments, maybe I'll live another few years longer.

01:23:45And that then means that gives scientists even more time to develop the second or the third round of these treatments.

01:23:50Of course, it's going to take time to develop interventions, but I'm certain that at some point, two teenagers will have a conversation with each other, and they'll be looking at their history books, and they'll be commenting something like,

01:24:04Oh my God, people just withered and died. Isn't that so tragic?

01:24:08The same way as we look at, you know, people just two lifetimes ago and not having an anesthetic or an antibiotic.

01:24:14And, you know, we look back and we go, jeez, that's horrendous.

01:24:20When it happens, though, it's completely a product of what we do.

01:24:23How much effort and money and energy we put into this to create a movement of people utterly engaged in keeping people healthy as long as possible.

01:24:33Hi, everyone. I hope you guys feel like you're among your people, like-minded people trying not to die.

01:24:41I'm happy you came.

01:24:42I love you.

01:24:46Are you happy?

01:24:48Never been happier in my entire life.

01:24:50I don't know if I can do it.

01:24:52I've never seen him happier than he is now.

01:24:55And just think about that.

01:24:56When you're content with who you are, and you're engaged in a project that is everything that you want to do,

01:25:02doesn't that set up as a happy place?

01:25:04To hear him say to me, I've never been happier in my life, I think releases me from worry, knowing that he can go on like this.

01:25:18You know, I've experienced wanting to die intensely, and now I'm in a situation where I want to live with everything that I am.