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  • 7 months ago
From something as familiar as our bodies to things vast as the formation of galaxies, we can observe the process of self-assembly, or when unordered parts come together in an organized structure. Skylar Tibbits explains how we see self-assembly at work in biology and chemistry -- and even in our future technologies.

Lesson by Skylar Tibbits, animation by London Squared Productions.
Transcript
00:00Music
00:14Have you ever wondered how things are built within our bodies?
00:17Why our bodies can regrow and repair themselves?
00:20And how we can pass on genes from one generation to the next?
00:23Yet none of our man-made objects have these traits.
00:25They're simply thrown away when they break and they definitely can't reproduce.
00:29The answer lies in something called self-assembly.
00:32Self-assembly is a system where unordered parts come together in an organized structure,
00:36completely on their own.
00:38This means that a pile of parts on your desk should in theory be able to move around on their own,
00:42find one another, and build something useful.
00:45This seems impossible like Transformers or the Sandman,
00:48but it's exactly how our bodies are built, how our immune system works, and why we can reproduce.
00:53Self-assembly is the factory and copy machines within our bodies
00:57that make proteins fold and DNA replicate.
01:00It's a process that not only happens in the biological and chemical world,
01:03but is a phenomenon that can be seen from magnets to snowflakes, robotics, social networks,
01:08the formations of cities and galaxies, to name just a few.
01:12In biology and chemistry, self-assembly is everywhere from atomic interaction,
01:16cellular replication, to DNA, RNA, and protein folding.
01:20Proteins are like bicycle chains with sequences of amino acid links.
01:24They self-assemble into 3D structures because of the interaction between the amino acids along the chain,
01:29as well as the relationship between the chain and the environment.
01:32These forces make the flexible chain fold into a 3D shape that governs the function of the protein.
01:38Viruses, on the other hand, are like soccer balls.
01:41They're made up of a series of subunits with specific shapes.
01:44Those shapes have attraction to one another, so they fit together in precise ways.
01:48Imagine you want to build a perfect sphere.
01:51It turns out that making a precise sphere through traditional means is actually quite difficult.
01:56Alternatively, you could try to self-assemble the sphere.
01:59One way would be to inflate the sphere like a bubble or a balloon.
02:02Another option would be to create many identical pieces that would come together to make a perfect sphere.
02:07You could try to put the pieces together one by one, but it might take a long time and you'd still have human errors.
02:13Instead, you could design a connection between the components like magnets and dump them into a container.
02:19When you shook the container, all the parts would find one another and build the sphere for you.
02:24Self-assembly is being used as a new design, science, and engineering tool for making the next generation of technologies
02:30easier to build, more adaptive, and less reliant on fossil fuels.
02:35Scientists are now making molecular microchips for computers where small molecular elements are given the right conditions
02:41to form themselves into organized pathways.
02:44Similarly, we can now use self-assembly as a way to make 3D structures with DNA,
02:48like capsules that could deliver drugs inside the body, releasing them only if certain conditions are met.
02:54Soon, self-assembly will be used for larger applications, where materials can repair themselves,
03:00water pipes can reconfigure on demand, buildings can adapt on their own to environment or dynamic loading,
03:07and space structures can self-assemble without humans.
03:10Imagine if our factories were more like organisms or brains,
03:14and our construction sites were like gardens that grow and adapt independently.
03:18The possibilities are endless, and it's now up to us to design a better world through self-assembly.
03:40And so…
03:50we're all about to be able to construct your power so that the way the places you are going to launch the body,
03:53and the ones that want to be built to maintain the mind of the body,
03:54to be in the body of the body.
03:55And so…
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