00:00The categories of fragile patients are numerous, they are all those people who have diseases
00:13that on the one hand can cause immunodepression, immunocompromission in itself, and on the
00:20other hand this immunocompromission can be caused by therapies that must be done following
00:27the presence of these pathologies.
00:29Specifically, there are certainly all people with respiratory pathologies, with cardiovascular
00:36pathologies, with chronic pathologies, for example, of the kidney, therefore chronic nephropathy,
00:45oncological patients and many others.
00:49I would like to add to these categories, however, the fact that even the caregivers, that is,
00:55those who take care of these people, must be immunized because it is necessary to create
01:01a protective shell around the fragile patients so that it is really impossible for these
01:10patients to come into contact with the virus.
01:13Why is it important to vaccinate them?
01:15Because the influenza virus, which is not absolutely banal as they say, in these patients
01:22can cause serious effects that have to do with the fact that their immune system is compromised
01:31and therefore they can hardly respond to an infectious insult in an adequate way, and
01:38on the other hand, these pathologies can aggravate, infectious pathologies can aggravate the basic
01:44pathologies.
01:45We know that over 65 years old vaccinated people are preferred, let's focus on citizens
01:51under 60 years old with cardiovascular pathologies.
01:54What is the position of scientific societies, including SITI, that represents them, regarding
01:59the vaccination of this at-risk population?
02:01Among these there are the elderly, but also all people who are not elderly but suffer
02:09from a chronic pathology.
02:11Specifically, subjects with cardiovascular pathologies can have very important severe
02:18reactions, especially a series of physiopathological mechanisms as a reaction to influenza, and
02:28this is why the enhanced vaccines are recommended for these subjects, even if they are younger,
02:38but with an immune system and a basic pathology that is very responsive, in some way in a
02:47negative way to the influenza virus.
02:51For the elderly, we know that there are vaccines more recommended than others because we know
02:59that the immune system is less productive, let's say, in the younger patients, the recommendations
03:11of these two societies are to express a fundamental clinical judgment, that the clinical colleagues
03:18instead become carriers of the sensitization of an elderly subject to the fact that the
03:26vaccination will not only not worsen their basic pathology, but rather it will be a help
03:33to continue to cure, to chronicize their pathology and, in the best hypothesis we hope, to cure it.
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