Marcus Cox raced 59 yards for a touchdown on Appalachian State's first play from scrimmage, setting the tone for a 31-13 defeat of Wyoming on Saturday.
Four minutes later, Latrell Gibbs followed up with a 91-yard interception return to end Wyoming's first possession. It was his fourth interception in as many games.
Cox, who scored just 19 seconds into the game, finished with a season-best 178 yards on 15 carries and went over 3,000 yards for his career. Zach Matics hit a career-best 51-yard field goal, surpassing his previous best by 20 yards.
