Our goal was to determine the effects of the calcium/vitamin D regimen on blood pressure, plasma lipid and lipoprotein concentrations, and plasma glucose and insulin concentrations in low calcium consumers, independent of improvements in body weight and fat mass. Clinically proven to lower body weight, food intake, and boost serotonin in a dose of 1000 mg before or after major meal. Study is the first to demonstrate that calcium plus supplementation has a beneficial effect on blood lipids and lipoproteins in overweight or obese women during a weight-loss intervention.