Muscle engineered by Duke University team withstands cobra venom
- 9 years ago
Originally published on April 1, 2014
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In the latest breakthrough in tissue engineering, a Duke University research team grew mouse muscles that can heal itself. The muscle fibers were cultured in a pool of immature muscle stem cells, which are essential for muscle tissue regeneration.
"We got them to grow into strongly contracting fibers," the study's lead researcher Nenad Bursac said in a Quartz report. "This is the first time we've seen muscle fibers contract so strongly in the lab. It was comparable to the contracting forces you'd see in an actual mouse muscle."
The team also found that the lab-grown tissue was also able to fully repair itself after it was injected with cobra venom, which causes the muscle membranes to rupture after 30 minutes.
The muscle was then implanted into the backs of mice and covered with a glass window through which scientists monitored the tissue's growth and contractions. Within two weeks, the mouse's capillaries grew into the grafted tissue, showing that it has been integrated into its host. However, the scientists were unable to integrate the muscles to the mouse's neuronal system, which means that the tissue would not have the ability to respond to commands.
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In the latest breakthrough in tissue engineering, a Duke University research team grew mouse muscles that can heal itself. The muscle fibers were cultured in a pool of immature muscle stem cells, which are essential for muscle tissue regeneration.
"We got them to grow into strongly contracting fibers," the study's lead researcher Nenad Bursac said in a Quartz report. "This is the first time we've seen muscle fibers contract so strongly in the lab. It was comparable to the contracting forces you'd see in an actual mouse muscle."
The team also found that the lab-grown tissue was also able to fully repair itself after it was injected with cobra venom, which causes the muscle membranes to rupture after 30 minutes.
The muscle was then implanted into the backs of mice and covered with a glass window through which scientists monitored the tissue's growth and contractions. Within two weeks, the mouse's capillaries grew into the grafted tissue, showing that it has been integrated into its host. However, the scientists were unable to integrate the muscles to the mouse's neuronal system, which means that the tissue would not have the ability to respond to commands.
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Welcome to TomoNews, where we animate the most entertaining news on the internets. Come here for an animated look at viral headlines, US news, celebrity gossip, salacious scandals, dumb criminals and much more! Subscribe now for daily news animations that will knock your socks off.
Check out our Android app: https://play.google.com/store/apps/details?id=com.nextmedia.gan
Check out our iOS app: https://itunes.apple.com/app/to