00:04What is the variety of breast cancer?
00:08There are as many types of breast cancer as there are breast cancer patients.
00:13Each patient's tumor contains up to several different tumors within that tumor.
00:19In other words, the variety is so great that it's not practical.
00:24And then what we do is classify it following a series of things that allow us to treat it.
00:31Triple-negative breast cancer is negative for all sectors: progesterone, estrogen, and GER2.
00:37This is what makes it such an aggressive cancer, because you can't find a treatment that is targeted.
00:44for him.
00:44What is currently being done is a combination of therapies, chemotherapy and immunotherapy to treat it.
00:53Triple-negative breast cancer still needs improved treatment, better therapies so that more patients can benefit.
01:03and have a higher survival rate.
01:05We want to develop vaccines against cancer. We believe that will improve patient survival rates.
01:19Immunotherapy is an excellent therapy that has shown great results in triple-negative breast cancer.
01:2565% of patients diagnosed with cancer in early childhood survive.
01:31In other words, it has greatly increased survival rates.
01:35It is true that not all patients can benefit from this, and that is what we researchers want to address.
01:40to these patients and be able to give them therapy.
01:47The immune system is a super-powerful machine we have in our body that is constantly working every day.
01:57with viral and bacterial infections.
02:00And we all surely remember the coronavirus, where having a vaccine against the virus helped a lot with the pandemic.
02:09What we want to do is practically the same thing, but to get the immune system to eliminate tumors.
02:19These microproteins are super-tiny proteins that have gone unnoticed until now.
02:24They are so tiny that we didn't even know they existed.
02:27Thanks to the techniques we currently have, we are able to begin to see them and see what they do.
02:37Once diagnosed, we would simply need to take a sample, analyze it by PCR, prepare the vaccine, and inject it.
02:46The body will begin to produce these microproteins, and this will activate the immune system, which will then prepare a tiny
02:54army
02:54to try to search the entire body for these microproteins until it reaches the tumor and extracts them from the tumor
03:00and delete it.
03:02So for a patient, it could mean a specialized vaccine that will eliminate her tumor.
03:08What we're doing is telling it to look for these microproteins wherever you find them in the body.
03:15And well, that's what we hope will happen.
03:18Always in combination with the treatments that exist today.
03:30Well, INTEOS plays a role primarily as a bridge and facilitator of research.
03:36On the one hand, we try to make these wonderful projects known among potential donors and society in general.
03:46And on the other hand, we try to find the necessary funding so that they can move forward.
03:55Microproteins are difficult to see, so having the money from the INTEOS Foundation has allowed us to make antibodies for
04:04to be able to start watching them.
04:06And we can also begin to study what their function is, where they are, what they attach to, and why they work.
04:13We like to quote a phrase from Mother Teresa who said that small drops make an ocean.
04:19Suddenly someone will come and take us out of the lab, let us tell people this, and allow us to
04:28so that people can support us in some way,
04:31For us, it's impressive.
04:33Not only on an economic level, but on a human level.
04:42Our life is about constantly trying to do what we think we have to do, which is the project.
04:48with the resources we had to obtain based on what we thought was going to happen.
04:55And then suddenly someone comes along and says, don't worry, everything you think you need,
05:03Here's the money to do it.
05:06Man, it's like suddenly, you know?
05:10And there comes a point when you say, should it always be like this?
05:21We almost never see the patients.
05:24I was very impressed by a patient who came to the laboratory one day.
05:29and had a diagnosis of triple-negative breast cancer,
05:34From what she said, things weren't going very well, but she wasn't there to talk about herself.
05:40She came to tell me that after her diagnosis,
05:45They had tried to find as much money as possible to boost the research.
05:53And what he had done was make keychains; he had sold a lot of keychains.
05:58And he came, I think it was with about three thousand euros for us to work.
06:05And what she told me is that what we were probably going to do in the lab
06:10It wouldn't be of any use to her anymore.
06:13But she thought that the most important thing after her diagnosis was...
06:18It was about trying to improve on what other women might go through.
06:24And that left a huge mark on me.
06:27And I even thought, what strength must this girl have?
06:33to avoid thinking about her and to think about others.
06:37I was really impressed and he gave me a keychain.
06:40And there it is, next to the computer.
06:43And the truth is that many times it's nighttime
06:47And I see the keyring and I say, come on, a little more.
06:57We support each other so much and inspire each other so much
07:02That means that whenever there's bad news, a bad result,
07:07It's like we all get pumped up together.
07:10And I even have to do the opposite,
07:12I have to say, hey, and stop, because everyone's...
07:15And we could do it, and we could do it.
07:17We work very hard,
07:19But we cannot promise that we will get a vaccine.
07:23We can only promise that we will work.
07:29On the one hand, it implies complete trust in the team behind it.
07:33And on the other hand, patience,
07:36because research takes time,
07:38The results are not immediate.
07:40and therefore, our commitment to the ALBA project
07:42must be maintained over time
07:44so that researchers can continue to make progress
07:48and that they have all the help possible to carry out the project.
07:56It was very special to meet Puri at one of the charity meals.
08:00which we celebrate this year
08:02and, above all, to hear her talk about the project,
08:05of the entire team behind it,
08:07of all the progress they are making
08:09and the enthusiasm and hope with which he speaks.
08:13It was very emotional
08:14And we saw there the possibility of transferring that whole conversation
08:18also to all consumers,
08:21to all the people who are part of Pompadour,
08:23so that they would understand and humanize
08:27everything that is research.
08:30I was super convinced
08:32that I was going to spend the whole time saying
08:33Thank you, thank you, thank you, thank you,
08:35because you don't know what's going to happen.
08:38And what I found
08:39It's a group of superhuman people,
08:43super curious,
08:44because the meal was a barrage of constant questions,
08:49Super interesting.
08:58The idea for Tocaté comes from a very simple idea
09:01And that's the five minutes it takes for your drink to infuse,
09:05It's the perfect time to take a few minutes
09:09to explore yourself
09:10and use it as a reminder to take care.
09:13Young people tend to think
09:15that we're not going to get something like cancer
09:18or to step over
09:22some signal that we can detect
09:24and we wanted to remember
09:26that at any time
09:28Can you spare a minute?
09:30to identify any changes
09:32that may have been in your body
09:33and always consult with a professional.
09:40Your body is your home
09:41And you have to take care of it and love it as such.
09:43In the end, your body is incredibly kind to you.
09:47It allows you to dream,
09:48It allows you to live
09:49And we have to give him back a little bit.
09:51and take care of ourselves
09:52and thank the body
09:54for everything it gives us.
09:55In addition, it's super important to know our body
09:58to be able to identify small things
09:59that may be rare,
10:00that are not common
10:01and always go to a professional
10:04so that he can help us.
10:05The information for this
10:06He always gives you the key
10:07to eliminate that fear,
10:09that uncertainty
10:09and to know and have the information
10:13It allows us to know
10:14What are the next steps?
10:16knowing how to examine ourselves,
10:18knowing that we have to go
10:19with a professional
10:20and also not generate that excessive fear.
10:26From Pompadour
10:27What we do is take advantage
10:28that our product
10:29It enters many homes
10:30to start the conversation
10:32in a close way
10:33beyond the revenue
10:36It comes with the objective
10:37to raise awareness and disseminate
10:39everything that the project entails
10:41and the work they are doing
10:42the researchers.
10:43Thank you!
10:44Thank you!
10:46Thank you!
10:47Thank you!
10:47Thank you!
