00:00Today, the hemophilia is in relation to blood-related related disorders.
00:08It is so small or small that the whole world of hemophilia has grown up with the hemophilia.
00:18How can the hemophilia get rid of the hemophilia?
00:22can be used in the whole world today. What is it? Why is the hemophilia? Why is the hemophilia?
00:37What is the hemophilia, thalassemia, sickle selenemia? What is the basic difference?
00:48What is the hemophilia? What is the hemophilia?
00:51Dr. Abhishek Ranjanj sir, we talk about it. Sir, this is the hemophilia today.
00:59The first question is, how much the hemophilia is in the whole world?
01:06What is the hemophilia?
01:09Sir, the hemophilia is a genetic disease.
01:15Almost 25% of patients have no hemophilia.
01:21This is a very complex disease.
01:25This is the hemophilia.
01:26This is the hemophilia.
01:30This is the hemophilia.
01:30If we don't give them the hemophilia,
01:34then the patients are handicapped.
01:37The joints of the hemophilia, the barbara bleeding,
01:40they are handicapped.
01:42The hemophilia is the hemophilia.
01:46If the hemophilia is a genetic disease,
01:48then they are handicapped too.
01:49It is a genetic disease.
01:49The other people have differentletes in the country.
01:54In some places of these countries,
01:55they are soue primal diseases.
01:58My family is a very happy parent.
01:59This is the hemophilia.
02:01This has been the hemophilia.
02:12The hemophilia.
02:13I was very much thankful to have these diseases.
02:14and the genes are transferred to males.
02:17So males are affected and females are carried away from the genes.
02:22And the manifestations of females are not the same,
02:26but females are also carried away from a carrier state.
02:29The patients present with excessive menstrual bleeding
02:33or post-bottom hemorrhage in my law.
02:37So they also identify the genes.
02:38They are very important to identify the genes.
02:41Some of them listen to them
02:43that some of the female's death has been found.
02:48So there is a high suspicion of females
02:51that the hemophilia gene is carried away from them.
02:54The females are not the same,
02:57but males are the same as the same as the male's bleeding.
03:00There is a question,
03:02how do you understand them?
03:04How do you understand them?
03:06How do you understand them?
03:07The male's child is hemophilic?
03:11Sir, this is basically
03:13the mild, moderate and severe category.
03:17The severe category of patients are more common.
03:21When the child is born in the 4-6 months,
03:27the child starts crawling,
03:29the trauma of the joints
03:37and the severe hemophilia
03:38the severe hemophilia
03:39the children of the 6 months and 8 months
03:40are present with the joint swelling
03:43and the severe hemophilia
03:44is present with the joint swelling.
03:44In addition,
03:45the severe hemophilia
03:46will be very excessive bleeding.
03:48Mild and moderate hemophilia
03:50are clinically silent
03:53unless they don't have any hemostatic challenge.
03:57It means they will be excessive bleeding
03:58when they have cut or trauma
04:01and they will be so bad.
04:02And the mild hemophilia
04:05are present with the post-operative bleeding
04:08and they will manifest
04:09with the post-operative bleeding
04:09or the tooth extraction
04:11will be excessive bleeding
04:13or the operation
04:16after that they will be excessive bleeding.
04:18What is the diagnosis?
04:19What is the diagnosis?
04:20Because as we know
04:22that in the world
04:23or in the world
04:24or in the world
04:25there is a very gap
04:27in this disease.
04:29Yes,
04:29you are saying
04:31that
04:31today
04:32there is no
04:33dedicated coagulation lab
04:35where we can
04:36do a timely diagnosis
04:37for patients
04:37or for bleeding
04:38or clotting disorders
04:39we can do
04:41a timely diagnosis
04:43so
04:44for diagnosis
04:45is very important
04:46that
04:46for patients
04:47who are symptomatic
04:48and have clinical features
04:50present
04:51they have basic
04:53such as
04:53CBC
04:54or platelet count
04:55and
04:56you have PT
04:57or APTT
04:58and
04:59factor assess
05:00factor 8
05:01or factor 9
05:02they have basic tests
05:04to know
05:05which patient
05:07has hemophilia
05:08or not.
05:08So
05:09clinical
05:09is important
05:10that
05:11clinical features
05:12in hemophilia
05:13fit
05:13or not
05:14not
05:14or
05:14patient
05:15has a detailed history
05:17along
05:18which
05:19goes to lab
05:19investigations
05:20and
05:20how many
05:23are registered
05:24hemophilia
05:25cases
05:26and what
05:26you see
05:29say
05:30almost
05:301,000
05:31patients
05:32both
05:33hemophilia
05:331,000
05:34to 1200
05:35hemophilia
05:36and
05:37b
05:37patients
05:37registered
05:3890%
05:57hemophilia
05:59have
05:59the
06:03treatment
06:04is
06:04factor
06:06prophylaxis
06:06is
06:06a
06:07what
06:07is
06:07what
06:08is
06:08what
06:10what
06:25treatment
06:30is
06:31the
06:32hemophilia
06:33and
06:33the
06:33treatment
06:33is
06:34the
06:34most important
06:35question
06:36is
06:36the
06:38treatment
06:39of
06:40hemophilia
06:40in
06:42the
06:42district
06:42we can
06:43reach
06:44but
06:45there are
06:46challenges
06:48that
06:49the
06:50maximum
06:51there are
06:52factors
06:52not
06:53no doubt
06:54I
06:55accept
06:55the
06:57emergency
06:58care
06:59is
06:59especially
07:00if
07:02children
07:03are
07:04bleeding
07:05then
07:06what
07:07does
07:07do
07:08now
07:10our
07:11king
07:11definitely
07:12is
07:12a
07:13huge
07:14but
07:15thanks
07:16to
07:17new
07:17treatment
07:18modalities
07:19we
07:20have
07:20some
07:20factors
07:21that
07:21we
07:21provide
07:25month
07:25we
07:26have
07:26month
07:26we
07:27don't
07:27a
07:27month
07:40have
07:41a
07:41we
07:42have
07:49month
07:49prophylaxis
07:49slowly
07:50we
07:50have
07:54question
07:55when
07:55a
07:56child
07:57is
07:58a
08:00life
08:01is
08:02a
08:04science
08:05developed
08:05a
08:06gene
08:07therapy
08:07and
08:07the
08:08child
08:09is
08:09a
08:12gene
08:13therapy
08:14is
08:14available
08:14for
08:15hemophilia
08:15but
08:16this
08:16is
08:16not
08:17available
08:18but
08:19we
08:21have
08:22wonderful
08:22drugs
08:23we
08:23have
08:23wonderful
08:25drugs
08:25before
08:26we
08:27have
08:27three
08:28patients
08:30we
08:31new
08:32molecules
08:32we
08:33give
08:33new
08:34molecules
08:34we
08:34have
08:35molecules
08:36we
08:39have
08:57molecules
08:59and
09:00we
09:01can
09:03take
09:03them
09:04once
09:05in
09:06month
09:06prophylaxis
09:07we
09:09have
09:10a
09:11life
09:11we
09:11have
09:12a
09:12is
09:14the
09:14question
09:14is
09:15the
09:15people
09:16are
09:17the
09:18people
09:20who
09:22are
09:23what
09:23is
09:24what
09:25is
09:25what
09:25a
09:27motivation
09:27that
09:27you
09:28have
09:29a
09:34motivation
09:35to
09:36to
09:37prophylaxis
09:38that
09:40they
09:41are
09:44handicapped
09:46and
09:46if
09:47we
09:47give
09:47prophylaxis
09:5599%
09:57of
09:58prophylaxis
09:58is
09:59a
10:00good life
10:01that
10:01is
10:02good life
10:03is
10:03good life
10:04is
10:04a
10:04good life
10:06because
10:15of
10:16repeated
10:16bleeding
10:16so
10:17we
10:18take
10:20them
10:21to
10:24their
10:26reservation
10:26so
10:27that
10:29their
10:29family
10:31can
10:32their
10:32life
10:33with
10:33Dr.
10:38Abhishek
10:38Ranjan
10:39said
10:40that
10:41hemophilia
10:41is
10:42very
10:43good
10:44but
10:44it
10:45necessary
10:46to
10:46how
10:48this
10:48disease
10:48can
10:49disease
10:51and
10:52disease
10:52can
10:53as
10:53as
10:54as
10:54as
10:55as
10:55them
10:55from
10:56to
11:01which
11:03can
11:03live
11:04and
11:09could
11:09be
11:10sure
11:10they
11:10can
11:10live
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