00:00coughing has been a human experience since time immemorial serving as a vital reflex to clear the
00:09airway of inhaled foreign matter chemical irritants or excess secretions from conditions
00:14like the common cold this physiological response can be both voluntary and involuntary while the
00:21act of coughing is ancient dedicated remedies such as cough drops only emerged around 1000 bc in
00:28egypt early egyptian remedies involved crafting the first hard candies from honey flavored with herbs
00:36spices and citrus fruits it was observed that sucking on these lozenges provided relief from
00:42coughing a principle that remains effective with today's cough drops whose ingredients are
00:47surprisingly similar medicines designed to reduce the frequency and intensity of coughing are
00:54technically known as antitussives many modern antitussives like codeine work by acting on the
01:00brain's cough center thereby common cough spasms however the earliest formulations in contrast
01:07focused on soothing and relaxing the throat muscles involved in the coughing mechanism
01:12throughout various cultures and eras the fundamental approach to cough relief remained consistent
01:18primarily altering the ingredients used historical remedies included substances like slippery elm bark
01:25eucalyptus oil peppermint oil and marshmallow root it wasn't until the 19th century that the first
01:32compounds designed to suppress or eliminate coughs by acting on the brain were developed today codeine a mild
01:39derivative of morphine is a common example given that high doses of morphine compounds can be fatal by
01:46interrupting respiration it's understandable how such substances effectively suppress coughing
01:53most over-the-counter cough preparations available today are complex combinations of cough suppressants
01:58expectorants decongestants and antihistamines these varied combinations are formulated to address different types of symptoms
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